scholarly journals Disparities in uptake of BRCA1/2 genetic testing in a randomized trial of telephone counseling

2014 ◽  
Vol 17 (6) ◽  
pp. 467-475 ◽  
Author(s):  
Morgan Butrick ◽  
Scott Kelly ◽  
Beth N. Peshkin ◽  
George Luta ◽  
Rachel Nusbaum ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Randomized Trial ◽  
Telephone Counseling

Disparities in Uptake of BRCA1/2 Genetic Testing in a Randomized Trial of Telephone Counseling

2015 ◽  
Vol 70 (10) ◽  
pp. 614-616
Author(s):  
Morgan Butrick ◽  
Scott Kelly ◽  
Beth N. Peshkin ◽  
George Luta ◽  
Rachel Nusbaum ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Randomized Trial ◽  
Telephone Counseling

A Randomized Trial Comparing the Effects of Self-Help Materials and Proactive Telephone Counseling on Teen Smoking Cessation.

2004 ◽  
Vol 23 (4) ◽  
pp. 397-406 ◽  
Author(s):  
Isaac M. Lipkus ◽  
Colleen M. McBride ◽  
Kathryn I. Pollak ◽  
Rochelle D. Schwartz-Bloom ◽  
Elizabeth Tilson ◽  
...  
Keyword(s):  
Smoking Cessation ◽  
Randomized Trial ◽  
Telephone Counseling ◽  
Self Help

scholarly journals Comparing Telephone Counseling With Reminding to Promote On-Time Repeated Mammography: A Randomized Trial in a Cohort With 4 Years Follow-Up

2019 ◽  
Vol 47 (1) ◽  
pp. 37-46
Author(s):  
Mary E. Costanza ◽  
Roger Luckmann ◽  
Christine Frisard ◽  
Mary Jo White ◽  
Caroline Cranos
Keyword(s):  
Confidence Interval ◽  
Randomized Trial ◽  
Odds Ratio ◽  
Multivariable Analysis ◽  
Telephone Counseling ◽  
Long Term Effects ◽  
Time Points ◽  
Reminder Call ◽  
Screening Mammograms

Background. Long-term continuous adherence to biennial screening mammograms as guidelines recommend remains low. Limited evidence suggests that reminder calls may increase short-term adherence as much as telephone counseling, but research is needed comparing the long-term effects of these two approaches. Purpose. To compare the impacts of two telephone outreach interventions and mailed reminders on 4-year continuous mammography adherence. Method. A cohort of 3,215 women, age 50 to 81 years, was selected from 30,160 women from a 4-year randomized trial of three interventions to promote biennial mammography: reminder letter only (LO), letter plus reminder call (RC), and two letters plus educational material and a counseling call (CC). Women selected remained eligible for the trial all 4 years and received annual interventions as needed. The proportion with a mammogram in the last 24 months was determined at baseline and four annual time points. Results. Continuous adherence at all four time points was higher in the RC (78.8%) and CC arms (78.8%) than in the LO arm (75.1%; p < .001). Multivariable analysis confirmed this finding: CC (odds ratio = 1.27; 95% confidence interval = [1.01, 1.61]) and RC (odds ratio = 1.23; 95% confidence interval = [0.98, 1.56]). Only 27.8% of women eligible for an initial counseling call actually received counseling. Conclusions. Compared with letters alone, outreach calls can modestly increase continuous mammography adherence among insured women with consistent primary care. Telephone counseling was no more effective than a reminder call, possibly due to limited acceptance of counseling calls by women who may find them unwelcome or unnecessary.

A randomized trial of two different genetic counseling interventions for BRCA1/2 genetic testing

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 1002-1002
Author(s):  
J. Garber ◽  
L. Digianni ◽  
M. Rue ◽  
K. Schneider ◽  
K. Shannon ◽  
...  
Keyword(s):  
Genetic Counseling ◽  
Genetic Testing ◽  
Randomized Trial ◽  
Counseling Interventions

Knowledge outcomes in a randomized trial of telephone vs. in-person disclosure of genetic testing: The COGENT study.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 1534-1534
Author(s):  
Nina Beri ◽  
Linda J. Patrick-Miller ◽  
Brian L. Egleston ◽  
Olufunmilayo I. Olopade ◽  
Michael J. Hall ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Randomized Trial ◽  
Genetic Knowledge ◽  
True Negative ◽  
Variant Of Uncertain Significance ◽  
Knowledge Change ◽  
Negative Results ◽  
Genetic Test Results ◽  
Uncertain Significance ◽  
Multivariable Analyses

1534 Background: Telephone disclosure (TD) of genetic testing is non-inferior to in-person disclosure (IPD) for most outcomes but did not meet non-inferiority for knowledge change. We sought to understand which concepts patients don’t understand and factors associated with lower knowledge. Methods: Patients were recruited to a multi-center, randomized trial (NCT01736345) comparing TD to IPD of genetic test results. 819 patients were randomized (IPD = 418; TD = 401); 165 declined randomization and requested IPD. Knowledge was assessed after pre-test counseling (V1) and test disclosure (V2). Results: There were no significant differences in genetic or multi-gene (MG) knowledge between disclosure groups after V1 and V2. On average, patients answered 73% (SD 1.19) of genetic knowledge and 57% (SD 1.78) of mg knowledge items correctly.After V1, most understood implications of a positive result (87%), that results are not deterministic (84%) and risks for their children (91%). Understanding of uninformative negative, true negative and variant of uncertain significance (VUS) results was lower (post-V1: 33%, 65%, 29%; post-V2 : 37%, 65%, 25%). In multivariable analyses, lower genetic knowledge after V1 was associated with study site, being older (p < 0.01), single (p < 0.01), non-white (p < 0.01), not Ashkenazi Jewish (p = 0.01), and not having a mutation in the family (p = 0.03), having more relatives with cancer (p < 0.01) and not graduating college (p < 0.01). Lower mg knowledge after V1 was associated with site and being non-white (p = 0.01). Lower genetic knowledge after V2 was not associated with disclosure method but associated with study site, being older (p < 0.01), not graduating college (p < 0.01) and being non-white (p < 0.01). Lower mg knowledge after V2 was only associated with not graduating college (p = 0.02). Conclusions: While there were no significant differences in genetic knowledge by disclosure method, understanding of several concepts (e.g. VUS and negative results) were lower regardless of arm. Several factors, including age, education and race/ethnicity were associated with lower knowledge. Interventions to improve genetic knowledge in real-world and diverse populations are needed. Clinical trial information: NCT07136345.

scholarly journals A randomized trial of the clinical utility of genetic testing for obesity: Design and implementation considerations

2013 ◽  
Vol 11 (1) ◽  
pp. 102-113 ◽  
Author(s):  
Catharine Wang ◽  
Erynn S Gordon ◽  
Catharine B Stack ◽  
Ching-Ti Liu ◽  
Tricia Norkunas ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Randomized Trial ◽  
Clinical Utility ◽  
Design And Implementation

scholarly journals Design of the Rural LEAP randomized trial: An evaluation of extended-care programs for weight management delivered via group or individual telephone counseling

2019 ◽  
Vol 76 ◽  
pp. 55-63 ◽  
Author(s):  
Michael G. Perri ◽  
Aviva H. Ariel-Donges ◽  
Meena N. Shankar ◽  
Marian C. Limacher ◽  
Michael J. Daniels ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Weight Management ◽  
Telephone Counseling ◽  
Extended Care

scholarly journals Randomized Trial of a Pharmacist-Delivered Intervention for Improving Lipid-Lowering Medication Adherence among Patients with Coronary Heart Disease

Cholesterol ◽  
2010 ◽  
Vol 2010 ◽  
pp. 1-11 ◽  
Author(s):  
Yunsheng Ma ◽  
Ira S. Ockene ◽  
Milagros C. Rosal ◽  
Philip A. Merriam ◽  
Judith K. Ockene ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Randomized Trial ◽  
Patient Adherence ◽  
Telephone Counseling ◽  
Lipid Lowering ◽  
Statin Prescription ◽  
Prescription Rates ◽  
One Year ◽  
Statin Adherence

A randomized trial of a pharmacist-delivered intervention (PI) versus usual care (UC) was conducted; 689 subjects with known coronary heart disease were recruited from cardiac catheterization laboratories. Participants in the PI condition received 5 pharmacist-delivered telephone counseling calls post-hospital discharge. At one year, 65% in the PI condition and 60% in the UC condition achieved an LDL-C level <100 mg/dL (P=.29); mean statin adherence was 0.88 in the PI, and 0.90 in the UC (P=.51). The highest percentage of those who reached the LDL-C goal were participants who used statins as opposed to those who did not use statins (67% versus 58%, P=.05). However, only 53% and 56% of the patients in the UC and PI conditions, respectively, were using statins. We conclude that a pharmacist-delivered intervention aimed only at improving patient adherence is unlikely to positively affect outcomes. Efforts must be oriented towards influencing physicians to increase statin prescription rates.

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