Genetic variation in social environment construction influences the development of aggressive behavior in Drosophila melanogaster

Abstract Differential success of sperm is likely to be an important component of fitness. Extensive variation among male genotypes in competitive success of sperm in multiply mated females has been documented for Drosophila melanogaster. However, virtually all previous studies considered the female to be a passive vessel. Nevertheless, under certain conditions female fitness could be determined by her role in mediating use of sperm from multiple males. Here we ask whether females differ among genotypes in their tendency to exhibit last-male precedence. Competition of sperm from two tester male genotypes (bwD and B3-09, a third-chromosome isogenic line from Beltsville, MD) was quantified by doubly mating female lines that had been rendered homozygous for X, second, or third chromosomes isolated from natural populations. The composite sperm displacement parameter, P2′, was highly heterogeneous among lines, whether or not viability effects were compensated, implying the presence of polymorphic genes affecting access of sperm to eggs. Genetic variation of this type is completely neutral in the absence of pleiotropy or interaction between variation in the two sexes.

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Genetic variation in the nutrition of Drosophila melanogaster—some general inferences

Proceedings of The Nutrition Society ◽

10.1079/pns19620028 ◽

1962 ◽

Vol 21 (2) ◽

pp. 169-178 ◽

Cited By ~ 5

Author(s):

Forbes W. Robertson

Keyword(s):

Drosophila Melanogaster ◽

Genetic Variation

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Genetic variation in cytochrome P-450-dependent demethylation in Drosophila melanogaster

Biochemical Pharmacology ◽

10.1016/0006-2952(87)90591-0 ◽

1987 ◽

Vol 36 (14) ◽

pp. 2279-2282 ◽

Cited By ~ 6

Author(s):

Inger Hällström

Keyword(s):

Drosophila Melanogaster ◽

Genetic Variation ◽

Cytochrome P 450

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Genetic variation in the dietary sucrose modulation of enzyme activities in Drosophila melanogaster

Genetics Research ◽

10.1017/s0016672300026094 ◽

1984 ◽

Vol 43 (3) ◽

pp. 307-321 ◽

Cited By ~ 27

Author(s):

Billy W. Geer ◽

Cathy C. Laurie-Ahlberg

Keyword(s):

Drosophila Melanogaster ◽

Genetic Variation ◽

Enzyme Activities ◽

Glycogen Synthesis ◽

Krebs Cycle ◽

Natural Populations ◽

Substitution Lines ◽

Chromosome Substitution Lines ◽

High Sucrose Diet ◽

Selection Of

SUMMARYGenetic variation in the modulating effect of dietary sucrose was assessed in Drosophila melanogaster by examining 27 chromosome substitution lines coisogenic for the X and second chromosomes and possessing different third isogenic chromosomes derived from natural populations. An increase in the concentration of sucrose from 0·1% to 5% in modified Sang's medium C significantly altered the activities of 11 of 15 enzyme activities in third instar larvae, indicating that dietary sucrose modulates many, but not all, of the enzymes of D. melanogaster. A high sucrose diet promoted high activities of enzymes associated with lipid and glycogen synthesis and low activities of enzymes of the glycolytic and Krebs cycle pathways, reflecting the physiological requirements of the animal. Analyses of variance revealed significant genetic variation in the degrees to which sucrose modulated several enzyme activities. Analysis of correlations revealed some relationships between enzymes in the genetic effects on the modulation process. These observations suggest that adaptive evolutionary change may depend in part on the selection of enzyme activity modifiers that are distributed throughout the genome.

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Genetic variation in Drosophila melanogaster pathogen susceptibility

Parasitology ◽

10.1017/s0031182006009929 ◽

2006 ◽

Vol 132 (6) ◽

pp. 767-773 ◽

Cited By ~ 53

Author(s):

M. C. TINSLEY ◽

S. BLANFORD ◽

F. M. JIGGINS

Keyword(s):

Biological Control ◽

Drosophila Melanogaster ◽

Genetic Variation ◽

Model Organism ◽

Resistance Evolution ◽

Control Programmes ◽

Host Ecology ◽

Insect Pathogens ◽

Immunological Research ◽

Pathogen Exposure

Genetic variation in susceptibility to pathogens is a central concern both to evolutionary and medical biologists, and for the implementation of biological control programmes. We have investigated the extent of such variation in Drosophila melanogaster, a major model organism for immunological research. We found that within populations, different Drosophila genotypes show wide-ranging variation in their ability to survive infection with the entomopathogenic fungus Beauveria bassiana. Furthermore, striking divergence in susceptibility has occurred between genotypes from temperate and tropical African locations. We hypothesize that this may have been driven by adaptation to local differences in pathogen exposure or host ecology. Genetic variation within populations may be maintained by temporal or spatial variation in the costs and benefits of pathogen defence. Insect pathogens are employed widely as biological control agents and entomopathogenic fungi are currently being developed for reducing malaria transmission by mosquitoes. Our data highlight the need for concern about resistance evolution to these novel biopesticides in vector populations.

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