scholarly journals Relationship between birth weight and retinal microvasculature in newborn infants

2011 ◽  
Vol 32 (6) ◽  
pp. 443-447 ◽  
Author(s):  
Y Kandasamy ◽  
R Smith ◽  
I M R Wright ◽  
L Hartley
Keyword(s):  
Birth Weight ◽  
Newborn Infants ◽  
Retinal Microvasculature

DIAGNOSIS OF IMPAIRED FETAL GROWTH IN NEWBORN INFANTS

PEDIATRICS ◽  
1971 ◽  
Vol 48 (4) ◽  
pp. 511-522 ◽  
Author(s):  
Herbert C. Miller ◽  
Khatab Hassanein
Keyword(s):  
Birth Weight ◽  
Soft Tissue ◽  
Body Length ◽  
Fetal Growth ◽  
Head Circumference ◽  
Soft Tissue Mass ◽  
Newborn Infants ◽  
Tissue Mass ◽  
Growth Impairment ◽  
Short Body

Measurements of crown-heel length, head circumference, and birth weight were made on a large number of newborn infants. Birth weight by itself was frequently not a valid measure of fetal growth impairment. By including measurements of body length and head size along with birth weight, four distinct patterns of fetal growth impairment were identified. The four patterns included infants who had abnormally short body lengths for dates, infants who had evidence of disproportionate growth between body length and head circumference, infants who accumulated excessive amounts of soft-tissue mass, and infants who accumulated too little soft-tissue mass. Criteria for diagnosing each pattern were obtained prospectively and have been presented with allowances made for the effects of race, sex, fetal age, and parity on each pattern. The separate identification of the four patterns provided a more precise description of fetal growth impairment than could be obtained from birth weight and calculated gestational age.

Neurotoxicity of Hexachlorophene in the Human: I. A Clinicopathologic Study of 248 Children

PEDIATRICS ◽  
1974 ◽  
Vol 54 (6) ◽  
pp. 689-695
Author(s):  
Robert M. Shuman ◽  
Richard W. Leech ◽  
Ellsworth C. Alvord
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Newborn Infants ◽  
Whole Body ◽  
Human Beings ◽  
Term Neonates ◽  
Experimental Animals ◽  
Clinicopathologic Study ◽  
Neurotoxic Effects ◽  
Sick Children

To assess the susceptibility of human beings to the neurotoxic effects of hexachlorophene demonstrated in experimental animals, a blind clinicopathologic analysis was made of 248 children coming to autopsy over a 7.5-year period in the two Seattle institutions to which practically all premature or sick children are referred. Repeated whole-body bathing of premature newborn infants in 3% hexachlorophene-bearing soap (undiluted pHisoHex) is associated with a vacuolar encephalopathy of the brainstem reticular formation. The prevalence of the vacuolar encephalopathy appears to be related to the number of exposures to hexachlorophene, to the concentration of hexachiorophene, to the birth weight (gestational age), to the length of survival and to the thoroughness of rinsing. From these observations we conclude that hexachlorophene should not be used on neonates under 1,400 gm birth weight and should be used only sparingly in full-term neonates with thorough rinsing.

scholarly journals Reduction of exposure to blood donors in preterm infants submitted to red blood cell transfusions using pediatric satellite packs

2013 ◽  
Vol 31 (3) ◽  
pp. 285-292 ◽  
Author(s):  
Cristina Lika Uezima ◽  
Ariane Moreira Barreto ◽  
Ruth Guinsburg ◽  
Akemi Kuroda Chiba ◽  
José Orlando Bordin ◽  
...  
Keyword(s):  
Birth Weight ◽  
Preterm Infants ◽  
Blood Donor ◽  
Blood Donors ◽  
Newborn Infants ◽  
Median Number ◽  
Erythrocyte Transfusion ◽  
Factors Associated ◽  
Group 2 ◽  
Group 1

OBJECTIVE: In preterm newborn infants transfused with erythrocytes stored up to 28 days, to compare the reduction of blood donor exposure in two groups of infants classified according to birth weight. METHODS: A prospective study was conducted with preterm infants with birth weight <1000g (Group 1) and 1000-1499g (Group 2), born between April, 2008 and December, 2009. Neonates submitted to exchange transfusions, emergency erythrocyte transfusion, or those who died in the first 24 hours of life were excluded. Transfusions were indicated according to the local guideline using pediatric transfusion satellite bags. Demographic and clinical data, besides number of transfusions and donors were assessed. . Logistic regression analysis was performed to determine factors associated with multiple transfusions. RESULTS: 30 and 48 neonates were included in Groups 1 and 2, respectively. The percentage of newborns with more than one erythrocyte transfusion (90 versus 11%), the median number of transfusions (3 versus 1) and the median of blood donors (2 versus 1) were higher in Group 1 (p<0.001), compared to Group 2. Among those with multiple transfusions, 14 (82%) and one (50%) presented 50% reduction in the number of blood donors, respectively in Groups 1 and 2. Factors associated with multiple transfusions were: birth weight <1000g (OR 11.91; 95%CI 2.14-66.27) and presence of arterial umbilical catheter (OR 8.59; 95%CI 1.94-38.13), adjusted for confounders. CONCLUSIONS: The efficacy of pediatrics satellites bags on blood donor reduction was higher in preterm infants with birth weight <1000g.

scholarly journals Early Postnatal Metabolic Profile in Neonates With Different Birth Weight Status: A Pilot Study

2021 ◽  
Vol 9 ◽  
Author(s):  
Serdar Beken ◽  
Saygin Abali ◽  
Neslihan Yildirim Saral ◽  
Bengisu Guner ◽  
Taha Dinc ◽  
...  
Keyword(s):  
Birth Weight ◽  
Amino Acid ◽  
Energy Metabolism ◽  
Gestational Age ◽  
Weight Status ◽  
Newborn Infants ◽  
Ponderal Index ◽  
Large For Gestational Age ◽  
Metabolic Disturbances ◽  
Intrauterine Growth

Introduction: Restricted or enhanced intrauterine growth is associated with elevated risks of early and late metabolic problems in humans. Metabolomics based on amino acid and carnitine/acylcarnitine profile may have a role in fetal and early postnatal energy metabolism. In this study, the relationship between intrauterine growth status and early metabolomics profile was evaluated.Materials and Methods: A single-center retrospective cohort study was conducted. Three hundred and sixty-one newborn infants were enrolled into the study, and they were grouped according to their birth weight percentile as small for gestational age (SGA, n = 69), appropriate for gestational age (AGA, n = 168), and large for gestational age (LGA, n = 124) infants. In all infants, amino acid and carnitine/acylcarnitine profiles with liquid chromatography-tandem mass spectrometry (LC-MS/MS) were recorded and compared between groups.Results: LGA infants had higher levels of glutamic acid and lower levels of ornithine, alanine, and glycine (p &lt; 0.05) when compared with AGA infants. SGA infants had higher levels of alanine and glycine levels when compared with AGA and LGA infants. Total carnitine, C0, C2, C4, C5, C10:1, C18:1, C18:2, C14-OH, and C18:2-OH levels were significantly higher and C3 and C6-DC levels were lower in SGA infants (p &lt; 0.05). LGA infants had higher C3 and C5:1 levels and lower C18:2 and C16:1-OH levels (p &lt; 0.05). There were positive correlations between free carnitine and phenylalanine, arginine, methionine, alanine, and glycine levels (p &lt; 0.05). Also, a positive correlation between ponderal index and C3, C5-DC, C14, and C14:1 and a negative correlation between ponderal index and ornithine, alanine, glycine, C16:1-OH, and C18:2 were shown.Conclusion: We demonstrated differences in metabolomics possibly reflecting the energy metabolism in newborn infants with intrauterine growth problems in the early postnatal period. These differences might be the footprints of metabolic disturbances in future adulthood.

Antibody to varicella zoster virus in low-birth-weight newborn infants

1978 ◽  
Vol 93 (3) ◽  
pp. 505-506 ◽  
Author(s):  
Richard K. Raker ◽  
Sharon Steinberg ◽  
Lewis M. Drusin ◽  
Anne Gershon
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Varicella Zoster Virus ◽  
Newborn Infants ◽  
Varicella Zoster

Colloid Osmotic Pressure in Newborn Infants: Variations with Birth Weight, Gestational Age, Total Serum Solids, and Mean Arterial Pressure

PEDIATRICS ◽  
1981 ◽  
Vol 68 (6) ◽  
pp. 814-819
Author(s):  
Paul Y. K. Wu ◽  
Gary Rockwell ◽  
Linda Chan ◽  
Shu-Mei Wang ◽  
Vikram Udani
Keyword(s):  
Blood Pressure ◽  
Birth Weight ◽  
Osmotic Pressure ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Newborn Infants ◽  
Colloid Osmotic Pressure ◽  
Large For Gestational Age ◽  
Total Serum ◽  
Arterial Blood

Colloid osmotic pressure (COP) of blood was measured directly at birth with the Wescor membrane colloid osmometer (model 4100) in 91 appropriately grown, 11 large, and nine small for gestational age "well" newborn infants. COP correlated directly with birth weight (r = .726, P &lt; .00001) and gestational age (r = .753, P &lt; .00001). COP values for small for gestational age (SGA) and large for gestational age (LGA) infants were found to fall within the 95% prediction interval with regard to birth weight and gestational age for appropriate for gestational age (AGA) infants. Simultaneous measurements of COP, total serum solids, and central arterial mean blood pressure were made. The results showed that COP correlated directly with total serum solids (r = .89, P &lt; .0001) and mean arterial blood pressure (r = .660, P &lt; .001). Among the factors evaluated, total serum solids was the best predictor of COP.

Cryptorchidism in the Newborn

PEDIATRICS ◽  
1973 ◽  
Vol 51 (2) ◽  
pp. 310-311
Author(s):  
Alfredo Santesteban
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Recent Article ◽  
Newborn Infants ◽  
Review Of The Literature ◽  
Undescended Testes ◽  
Low Birth Weight Infant ◽  
New Born ◽  
Born Infant ◽  
Infant Birth

The incidence of cryptorchidism in newborn infants is stated to be 3% to 4% by Curran and Curran in a recent article.1 The reference cited is a report by Scorer published in 1957.2 However, a review of the literature shows that the incidence of cryptorchidism in the full-term new born infant is slightly lower and in the low birth weight infant (birth weight 2,500 gm or less), it is considerably higher. Up until 1955 there was much confusion regarding the incidence of undescended testes in the newborn.

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