The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL

2.31 Phosphoinositide 3'-Kinase (PI3K) Delta Inhibition with CAL-101 (GS 1101) Significantly Alters Chemokines and Shows Increased In Vitro Activity in Unmutated IgVh CLL Compared to Mutated IgVh Samples

Clinical Lymphoma Myeloma & Leukemia ◽

10.1016/j.clml.2011.09.064 ◽

2011 ◽

Vol 11 ◽

pp. S178-S179

Author(s):

Stephen E. Spurgeon ◽

Luke B. Fletcher ◽

Sarah Meadows ◽

Brian Lannutti ◽

Russell T. Burke ◽

...

Keyword(s):

Vitro Activity ◽

In Vitro Activity ◽

M183 ACTIVATED PHOSPHOINOSITIDE 3-KINASE (PI3K) DELTA SYNDROME (APDS) MAY HIDE BEHIND EVOLVING MANIFESTATIONS IN EARLY CHILDHOOD

Annals of Allergy Asthma & Immunology ◽

10.1016/j.anai.2021.08.324 ◽

2021 ◽

Vol 127 (5) ◽

pp. S103

Author(s):

S. Kubala ◽

G. Uzel

Keyword(s):

Early Childhood ◽

Structural studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies

Biochemical Society Symposium ◽

10.1042/bss0740047 ◽

2007 ◽

Vol 74 (1) ◽

pp. 47 ◽

Cited By ~ 3

Author(s):

Hsiangling Teo ◽

David J. Gill ◽

Ji Sun ◽

Olga Perisic ◽

Dmitry B. Veprintsev ◽

...

Keyword(s):

Multivesicular Bodies ◽

Structural Studies ◽

15-Deoxy-.DELTA.12,14-prostaglandin J2 and Its Precursors Target Phosphoinositide 3-kinase and p38 MAPK to Accelerate Proliferation in the Human T Cell Leukemia Cell Line MOLT-4F

Journal of Oral Biosciences ◽

10.2330/joralbiosci.46.37 ◽

2004 ◽

Vol 46 (1) ◽

pp. 37-46

Author(s):

Yasutaka Azuma ◽

Kyoko Watanabe ◽

Masataka Date ◽

Shinya Shirasu ◽

Michiharu Daito ◽

...

Keyword(s):

T Cell ◽

Cell Line ◽

P38 Mapk ◽

Leukemia Cell ◽

Leukemia Cell Line ◽

T Cell Leukemia ◽

Cell Leukemia ◽

Human T Cell ◽

Prostaglandin J2

ACTIVATED PI3K-DELTA SYNDROME PRESENTING WITH MASSIVE MEDIASTINAL LYMPHADENOPATHY CAUSING BRONCHIAL COMPRESSION

10.26226/morressier.57bc1755d462b80290b4d790 ◽

2016 ◽

Author(s):

Marjolein Wentink

Keyword(s):

Mediastinal Lymphadenopathy ◽

Bronchial Compression ◽

Faculty Opinions recommendation of Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1012274.185076 ◽

2003 ◽

Author(s):

Steve Ward

Keyword(s):

Essential Role ◽

Directional Movement ◽

Faculty Opinions recommendation of Quantitative analysis of phagolysosome fusion in intact cells: inhibition by mycobacterial lipoarabinomannan and rescue by an 1alpha,25-dihydroxyvitamin D3-phosphoinositide 3-kinase pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1018663.211507 ◽

2004 ◽

Author(s):

Emanuela Handman

Keyword(s):

Quantitative Analysis ◽

Intact Cells ◽

Dihydroxyvitamin D3 ◽

Kinase Pathway

Faculty Opinions recommendation of Protein kinase activity of phosphoinositide 3-kinase regulates beta-adrenergic receptor endocytosis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1027692.326651 ◽

2005 ◽

Author(s):

Sharona Gordon

Keyword(s):

Protein Kinase ◽

Adrenergic Receptor ◽

Kinase Activity ◽

Protein Kinase Activity ◽

Beta Adrenergic Receptor ◽

Beta Adrenergic ◽

Receptor Endocytosis ◽

Faculty Opinions recommendation of Invasion of endothelial cells by Neisseria meningitidis requires cortactin recruitment by a phosphoinositide-3-kinase/Rac1 signalling pathway triggered by the lipo-oligosaccharide.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1027912.334872 ◽

2005 ◽

Author(s):

Emmanuelle Caron

Keyword(s):

Endothelial Cells ◽

Neisseria Meningitidis ◽

Signalling Pathway ◽

Faculty Opinions recommendation of Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1030894.365621 ◽

2006 ◽

Author(s):

Roger Williams

Keyword(s):

Class I ◽

Oncogenic Transformation ◽