scholarly journals Odontogenic Cysts, Odontogenic Tumors, Fibroosseous, and Giant Cell Lesions of the Jaws

2002 ◽  
Vol 15 (3) ◽  
pp. 331-341 ◽  
Author(s):  
Joseph A Regezi
2012 ◽  
Vol 70 (9) ◽  
pp. e55-e56
Author(s):  
P. Boffano ◽  
C. Gallesio ◽  
J. Roana ◽  
D. Scalas ◽  
S. Berrone ◽  
...  

2002 ◽  
Vol 81 (11) ◽  
pp. 757-760 ◽  
Author(s):  
D.C. Barreto ◽  
A.E. Bale ◽  
L. De Marco ◽  
R.S. Gomez

The human patched gene ( PTCH) functions in both embryologic development and tumor suppression. PTCH mutations have been found in odontogenic keratocysts. However, the expression and localization of the protein product of the gene have not been determined in odontogenic tumors and cysts. We investigated 68 odontogenic lesions by immunohistochemistry, and compared their PTCH expression with that in basal cell carcinomas. All odontogenic lesions, including two keratocysts with truncating mutations, were positive for PTCH. Different types of lesions had different amounts of staining. Lack of staining was noted in the majority of basal cell carcinomas. Taken together, these data suggest that odontogenic keratocysts arise with heterozygous mutations of the PTCH gene.


1992 ◽  
Vol 29 (5) ◽  
pp. 369-380 ◽  
Author(s):  
F. M. Poulet ◽  
B. A. Valentine ◽  
B. A. Summers

A retrospective histologic study of 12 canine and eight feline epithelial odontogenic tumors and cysts was conducted from oral masses ( n = 3,917) obtained between 1980 and 1990. No sex or breed predilection was identified. Ameloblastoma was observed in two dogs (case Nos. 1, 2) 6 and 8 months of age. Calcifying epithelial odontogenic tumors were seen in a dog (case No. 3) and in two cats (case Nos. 4, 5) between 8 and 16 years of age. Ameloblastic fibroma (or fibroameloblastoma) was observed in cats (case Nos. 6–10) only. Inductive fibroameloblastoma was observed in four cats (case Nos. 6–9) up to 1 year of age, whereas ameloblastic fibroma was seen in a 14-year-old cat (case No. 10). A single ameloblastic odontoma was identified in a 20-month-old dog (case No. 11). Two complex odontomas occurred in a 6-month-old (case No. 12) and a 4-year-old (case No. 13) dog. Odontogenic cysts were identified in five dogs (case Nos. 14–18) aged 4.5 months to 16 years and in a 1-year-old cat (case No. 19) and have not been previously reported in these species. These cysts were lined by a stratified epithelium reminiscent of the appearance of ameloblastic epithelium. An odontogenic keratocyst with prominent central parakeratotic keratinization was identified in one 9-year-old female dog (case No. 20). Almost all epithelial odontogenic tumors were circumscribed, benign tumors that warranted a good prognosis for survival, although local recurrence may have followed (or may follow) incomplete excision. Calcifying epithelial odontogenic tumors may be locally invasive. Of six odontogenic cysts (case Nos. 14–19), two (case Nos. 15, 18) gave rise to basi-squamous carcinomas. The classification and behavior of epithelial odontogenic tumors and cysts in human beings, dogs, and cats are discussed.


2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Ufuk Tatli ◽  
Özgür Erdoğan ◽  
Aysun Uğuz ◽  
Yakup Üstün ◽  
Yaşar Sertdemır ◽  
...  

Purpose. The objective of this study was to evaluate the diagnostic concordance characteristics of oral cavity lesions by comparing the clinical diagnosis of the lesions with the histopathologic diagnosis.Material and Method. A retrospective analysis was conducted on the patients, who were admitted with oral cavity pathology and underwent biopsy procedure between 2007 and 2011. The oral cavity lesions were classified into 6 different groups as odontogenic cysts, nonodontogenic cysts, odontogenic tumors, nonodontogenic tumors, malignant tumors, and precancerous lesions in accordance with the 2005 WHO classification. The diagnoses were also recategorized into 3 groups expressing prognostic implications as benign, precancerous, and malignant. The initial clinical diagnoses were compared with the histopathologic diagnoses. Data were analyzed statistically.Results. A total of 2718 cases were included. Histopathologic diagnosis did not match the clinical diagnosis in 6.7% of the cases. Nonodontogenic tumors and malignant tumors had the highest misdiagnosis rates (11.5% and 9%, resp.), followed by odontogenic tumors (7.7%), precancerous lesions (6.9%), and odontogenic cysts (4.4%). Clinicians were excelled in diagnosis of benign and precancerous lesions in clinical setting.Conclusion. The detailed discordance characteristics for each specific lesion should be considered during oral pathology practice to provide early detection without delay.


2021 ◽  
Vol 10 (12) ◽  
pp. e169101220140
Author(s):  
Lucas Nascimento Ribeiro ◽  
Raíssa Soares dos Anjos ◽  
Allan Vinícius Martins de Barros ◽  
Maíra Carla Oliveira Franklin Araújo de Lira ◽  
Julliana Carvalho Rocha ◽  
...  

Objective: This study aimed to evaluate the relative prevalence, demographic distribution and clinical-pathological characteristics of the maxillary odontogenics cysts and tumors of the jaws in a pathology laboratory located in a university hospital in Northeastern Brazil. Methods: An observational and retrospective study was carried out, in which information was collected on histopathological diagnosis, age, gender and location of the lesion of patients who had been diagnosed with odontogenic cysts or odontogenic tumors between 2013 and 2020.  Results: Among the 546 specimens, 57 were odontogenic cysts and 41 were odontogenic tumors. The most frequent odontogenic cysts were the odontogenic keratocyst 21 (21.4%) and the root cyst 19 (19.4%). The most frequent odontogenic tumors were ameloblastoma 27 (27.6%) and odontoma 6 (6.1%). Conclusion: The data found in this study are possibly associated with the service assistance profile.


2020 ◽  
Vol 9 (2) ◽  
Author(s):  
Silvestre Estrela Silva Júnior ◽  
Lukas Natã Mendes Fragoso ◽  
Nathalia da Cruz Flores ◽  
Laís dos Santos Novais ◽  
Maria Vitória Calado Ramalho dos Santos ◽  
...  

Introdução: Os odontomas são tumores odontogênicos benignos e os mais frequentes dos maxilares. Usualmente estão associados à dentição permanente em crianças e adultos jovens, sendo geralmente assintomáticos, podendo causar impactação dental. O aspecto radiográfico é de múltiplas calcificações, semelhantes ao dente, circundadas por um estreito halo radiolúcido, sendo o diagnóstico feito através de exames radiográficos de rotina. Objetivo: Este trabalho teve como objetivo relatar a remoção cirúrgica de um odontoma composto em região anterior da maxila, associado a dentes impactados, em um paciente pediátrico. Relato do caso clínico: Paciente do sexo masculino, 12 anos, foi referido ao serviço de cirurgia oral da Universidade Federal de Campina Grande, Campus Patos – PB, encaminhado pelo ortodontista. Durante anamnese não foram constatados comprometimento sistêmico. Ao exame físico foi observado abaulamento na região maxilar esquerda e retenção prolongada de alguns elementos, como também a ausência de outros. Analisada a radiografia panorâmica, foi observada massa radiopaca, na região anterior da maxila, sugestiva de odontoma composto, com impactação dental. Em decorrência da proximidade da lesão com os dentes anteriores superiores impactados e da localização do elemento 21, foi feita tomografia computadorizada por feixe cônico, o que facilitou o planejamento cirúrgico. O procedimento foi realizado sem intercorrências e no pós-operatório tardio, o paciente evolui satisfatoriamente. Conclusão: Pode-se concluir que o tratamento proposto foi eficaz e que a tomografia computadorizada por feixe cônico é um exame complementar de grande valia no diagnóstico de patologias, assim como no planejamento cirúrgico, devido à alta resolução e precisão das imagens obtidas.Descritores: Tumores Odontogênicos; Odontoma; Tomografia Computadorizada de Feixe Cônico.ReferênciasJayam C, Bandlapalli A, Patel N, Choudhary RS. A case of impacted central incisor due to dentigerous cyst associated with impacted compound odontome. BMJ Case Rep. 2014;2014:bcr2013202447.Abrahams JM, McClure SA. Pediatric Odontogenic Tumors. Oral Maxillofac Surg Clin North Am. 2016;28(1):45-58.Angiero F, Benedicenti S, Parker S, Signore A, Sorrenti E, Giacometti E et al. Clinical and surgical management of odontoma. Photomed Laser Surg. 2014;32(1):47-53.Neville BW, Damm DD, Allen CM, Bouquot JE. Patologia oral e maxilofacial. 4.ed. Rio de Janeiro: Elsevier, 2016.Bereket C, Çakır-Özkan N, Şener İ, Bulut E, Tek M. Complex and compound odontomas: Analysis of 69 cases and a rare case of erupted compound odontoma. Niger J Clin Pract. 2015;18(6):726-30. Malamed SF. Manual de anestesia local. 6. ed. Rio de Janeiro: Elsevier, 2013.Soluk Tekkesin M, Tuna EB, Olgac V, Aksakallı N, Alatlı C. Odontogenic lesions in a pediatric population: Review of the literature and presentation of 745 cases. Int J Pediatr Otorhinolaryngol. 2016;86:196-99.Wang YL, Chang HH, Chang JY, Huang GF, Guo MK. Retrospective survey of biopsied oral lesions in pediatric patients. J Formos Med Assoc. 2009;108(11):862-71.Al-Khateeb T, Al-Hadi Hamasha A, Almasri NM. Oral and maxillofacial tumours in north Jordanian children and adolescents: a retrospective analysis over 10 years. Int J Oral Maxillofac Surg. 2003;32(1):78-83.Guerrisi M, Piloni MJ, Keszler A. Odontogenic tumors in children and adolescents. A 15-year retrospective study in Argentina. Med Oral Patol Oral Cir Bucal. 2007;12(3):E180-85.Lima GS, Fontes ST, Araújo LMA, Etges A, Tarquinio SBC, Gomes APN. A survey of oral and maxillofacial biopsies in children: a single-center retrospective study of 20 years in Pelotas-Brazil. J Appl Oral Sci. 2008;16(6):397-402.Bernardes VF, Cota LOM, Costa FO, Mesquita RA, Gomez RS, Aguiar MCF. Gingival peripheral odontoma in child: case report of an uncommon lesion. Braz J Oral Sci. 2008;7(26):1624-26.Silva AR, Carlos-Bregni R, Vargas PA, de Almeida OP, Lopes MA. Peripheral developing odontoma in newborn. Report of two cases and literature review. Med Oral Patol Oral Cir Bucal. 2009;14(11):e612-15.Owens BM, Schuman NJ, Pliske TA, Culley WL. Compound composite odontoma associated with an impacted cuspid. J Clin Pediatr Dent. 1995; 19(4):293-95.Cildir SK, Sencift K, Olgac V, Sandalli N. Delayed eruption of a mandibular primary cuspid associated with compound odontoma. J Contemp Dent Pract. 2005;6(4):152-59.Altay MA, Ozgur B, Cehreli ZC. Management of a compound odontoma in the primary dentition. J Dent Child. 2016;83(2):98-101.Freires JFV. Remoção cirúrgica de odontoma composto de grande proporção sob anestesia local: relato de caso [monografia]. Patos (PB): Curso de Bacharelado em Odontologia, Universidade Federal de Campina Grande; 2017.Kignel S. Estomatologia – bases do diagnóstico para o clínico geral. 2.ed. São Paulo: Santos; 2013.Bilodeau EA, Collins BM. Odontogenic Cysts and Neoplasms. Surg Pathol Clin. 2017;10(1):177-22.Ladeinde AL, Ajayi OF, Ogunlewe MO, et al. Odontogenic tumors: a review of 319 cases in a Nigerian teaching hospital. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99(2):191-95.Chang JY, Wang JT, Wang YP, Liu BY, Sun A, Chiang CP. Odontoma: a clinicopathologic study of 81 cases. J Formos Med Assoc. 2003;102(12):876-82.Vázquez-Diego J, Gandini Pablo C, Carbajal Eduardo E. Odontoma compuesto: Diagnóstico radiográfico y tratamento quirúrgico de um caso clínico. Av Odontoestomatol. 2008;24(5):307-12.Teruhisa U, Murakami J, Hisatomi M, Yanagi Y, Asaumi J. A case of unerupted lower primary second molar associated with compound odontoma. Open Dent J. 2009;3:173-76.


Author(s):  
Anchal Bhat ◽  
Soham Mitra ◽  
Chetana Chandrashekar ◽  
Monica Solomon ◽  
Spoorti Kulkarni

Objectives. To determine the prevalence of odontogenic cysts and tumors along with age range, sex distribution, site of presentation and also to identify the most common type of odontogenic cyst and tumor among the population of coastal Karnataka over a 10-year period. Method. Data was collected from patient records and histologically diagnosed cases of odontogenic cysts and tumors. The age, gender of patients, as well as the site of lesion was recorded. Result. A total of 167 cases were retrieved. Among them, 125 cases were diagnosed as odontogenic cysts and 42 cases were odontogenic tumors. Radicular cyst was the most frequently diagnosed cyst and unicystic ameloblastoma was the most frequently diagnosed tumor. A strong predilection for males was observed for both the odontogenic cysts and odontogenic tumors. Odontogenic cysts were more commonly seen in individuals in the age range 21- 41 years, while odontogenic tumors were frequently seen in individuals in the age range 1-20 years. Conclusion. This study provides an epidemiological profile of odontogenic cysts and odontogenic tumors among a rural population of coastal Karnataka. There is a notable variation in demographic profile of odontogenic cysts and odontogenic tumors in this population when compared with other populations.


2011 ◽  
Vol 57 (6) ◽  
pp. 330-334
Author(s):  
Kaname TSUJI ◽  
Masahiro WATO ◽  
Sakiko MATSUDA ◽  
Yuki MATSUSHIMA ◽  
Teruyoshi HAYASHI ◽  
...  

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