Brain-derived neurotrophic factor Val66Met genotype and ovarian steroids interactively modulate working memory-related hippocampal function in women: a multimodal neuroimaging study

2017 ◽  
Vol 23 (4) ◽  
pp. 1066-1075 ◽  
Author(s):  
S-M Wei ◽  
E B Baller ◽  
P D Kohn ◽  
J S Kippenhan ◽  
B Kolachana ◽  
...  
Keyword(s):  
Working Memory ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Hippocampal Function ◽  
Multimodal Neuroimaging ◽  
Ovarian Steroids ◽  
Neuroimaging Study

Brain-Derived Neurotrophic Factor Val66Met Polymorphism in Contex of Executive Functions and Working Memory in Obese Patients

2018 ◽  
Vol 08 (01) ◽  
Author(s):  
Maciej Bieliaski ◽  
Natalia Lesiewska ◽  
Marcin Jaracz ◽  
Marta Tomaszewska ◽  
Marcin Sikora ◽  
...  
Keyword(s):  
Working Memory ◽  
Executive Functions ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Obese Patients ◽  
Val66met Polymorphism

scholarly journals Psychotic Experiences, Working Memory, and the Developing Brain: A Multimodal Neuroimaging Study

2015 ◽  
Vol 25 (12) ◽  
pp. 4828-4838 ◽  
Author(s):  
Leon Fonville ◽  
Kathrin Cohen Kadosh ◽  
Mark Drakesmith ◽  
Anirban Dutt ◽  
Stanley Zammit ◽  
...  
Keyword(s):  
Working Memory ◽  
Developing Brain ◽  
Psychotic Experiences ◽  
Multimodal Neuroimaging ◽  
Neuroimaging Study

scholarly journals Comparison of the effects of open- and closed-skill exercise on cognition and peripheral proteins: A cross-sectional study

PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0251907
Author(s):  
Evrim Gökçe ◽  
Emel Güneş ◽  
Fikret Arı ◽  
Serhat Hayme ◽  
Erhan Nalçacı
Keyword(s):  
Working Memory ◽  
Selective Attention ◽  
Neurotrophic Factor ◽  
Cathepsin B ◽  
Verbal Fluency ◽  
Acute Exercise ◽  
Brain Derived Neurotrophic Factor ◽  
Visuospatial Working Memory ◽  
Cross Sectional ◽  
Attention Tasks

Previous research indicates that different exercise modes might create different effects on cognition and peripheral protein signals. This study aimed to compare the effects of long-term participation in an open and closed-skill exercise on cognitive functions and Brain-derived neurotrophic factor and Cathepsin B levels. 18 fencers, 18 swimmers, 18 sedentary controls between 18–25 years old participated in the study. Participants performed visuospatial working memory, verbal fluency and selective attention tasks. Blood samples were tested for Brain-derived neurotrophic factor and Cathepsin B using ELISA. The results showed that fencers performed superiorly on some part of visuospatial working memory, verbal fluency, and selective attention tasks than swimmers and sedentary controls. Athlete groups showed higher scores on some subtests of visuospatial working memory and selective attention tasks than sedentary controls. The basal serum Brain-derived neurotrophic factor level was not significant between the groups, but Cathepsin B was higher in fencers than swimmers and sedentary controls. The peripheric protein signal response to acute exercise was significantly higher in athletes, particularly in the open-skill group for Cathepsin B. Our research provided noteworthy results that more cognitively challenging exercise may provide more benefits for some aspects of cognition. Since our findings suggest that open-skill exercise improves specific types of executive-control functioning, this exercise mode might be included in training programs to support cognition and prevent cognitive impairment.

scholarly journals Acute Effects of High-Intensity Interval Training on Brain-Derived Neurotrophic Factor, Cortisol and Working Memory in Physical Education College Students

2020 ◽  
Vol 17 (21) ◽  
pp. 8216
Author(s):  
Inmaculada C. Martínez-Díaz ◽  
María C. Escobar-Muñoz ◽  
Luis Carrasco
Keyword(s):  
College Students ◽  
Working Memory ◽  
Neurotrophic Factor ◽  
High Intensity ◽  
Interval Training ◽  
Brain Derived Neurotrophic Factor ◽  
Peak Power Output ◽  
High Intensity Interval Training ◽  
Single Bout ◽  
High Intensity Interval

High-intensity interval training (HIIT) is considered one of the most effective methods for improving cardiorespiratory and metabolic functions. However, it is necessary to clarify their effects on neurophysiological responses and coginitive functioning. Thus, this study aimed to determine the effects of an acute bout of HIIT on neurocognitive and stress-related biomarkers and their association with working memory (WM) capacity in healthy young adults. Twenty-five male college students performed a single bout of HIIT consisting of 10 × 1 min of cycling at their VO2 peak power output. Plasma Brain-Derived Neurotrophic Factor (BDNF) and cortisol (CORT) levels, and WM (Digit Span Test (DST)), were assessed pre-, post- and 30 min post-intervention. Significant post-exercise increases in circulating BDNF and CORT levels were observed coinciding with the highest DST performance; however, no statistical associations were found between cognitive and neurophysiological variables. Moreover, DST scores obtained 30 min after exercise remained higher than those assessed at pre-exercise. In conclusion, the stress induced by a single bout of HIIT induces a remarkable response of BDNF and CORT boosting WM capacity in healthy young males. Future research should clarify the association between cognitive and neurobiological markers during intense exercise stimulation.

scholarly journals Essential role of brain-derived neurotrophic factor in adult hippocampal function

2004 ◽  
Vol 101 (29) ◽  
pp. 10827-10832 ◽  
Author(s):  
L. M. Monteggia ◽  
M. Barrot ◽  
C. M. Powell ◽  
O. Berton ◽  
V. Galanis ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Essential Role ◽  
Brain Derived Neurotrophic Factor ◽  
Hippocampal Function
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