scholarly journals Real-time reliable determination of binding kinetics of DNA hybridization using a multi-channel graphene biosensor

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Shicai Xu ◽  
Jian Zhan ◽  
Baoyuan Man ◽  
Shouzhen Jiang ◽  
Weiwei Yue ◽  
...  
Keyword(s):  
Real Time ◽  
Dna Hybridization ◽  
Binding Kinetics ◽  
Reliable Determination ◽  
Kinetics Of

A suspension-cell biosensor for real-time determination of binding kinetics of protein–carbohydrate interactions on cancer cell surfaces

2013 ◽  
Vol 49 (85) ◽  
pp. 9908 ◽  
Author(s):  
Xueming Li ◽  
Yuxin Pei ◽  
Ruina Zhang ◽  
Qi Shuai ◽  
Feng Wang ◽  
...  
Keyword(s):  
Real Time ◽  
Cancer Cell ◽  
Binding Kinetics ◽  
Suspension Cell ◽  
Cell Surfaces ◽  
Time Determination ◽  
Kinetics Of ◽  
Cell Biosensor

scholarly journals Fabrication of Carbohydrate Chips Based on Polydopamine for Real-Time Determination of Carbohydrate–Lectin Interactions by QCM Biosensor

Polymers ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 1275 ◽  
Author(s):  
Kun Shang ◽  
Siyu Song ◽  
Yaping Cheng ◽  
Lili Guo ◽  
Yuxin Pei ◽  
...  
Keyword(s):  
Real Time ◽  
Con A ◽  
Quartz Crystals ◽  
Ulex Europaeus ◽  
Novel Approach ◽  
Ulex Europaeus Agglutinin I ◽  
Flow Through ◽  
Time Determination ◽  
Kinetics Of

A novel approach for preparing carbohydrate chips based on polydopamine (PDA) surface to study carbohydrate–lectin interactions by quartz crystal microbalance (QCM) biosensor instrument has been developed. The amino-carbohydrates were immobilized on PDA-coated quartz crystals via Schiff base reaction and/or Michael addition reaction. The resulting carbohydrate-chips were applied to QCM biosensor instrument with flow-through system for real-time detection of lectin–carbohydrate interactions. A series of plant lectins, including wheat germ agglutinin (WGA), concanavalin A (Con A), Ulex europaeus agglutinin I (UEA-I), soybean agglutinin (SBA), and peanut agglutinin (PNA), were evaluated for the binding to different kinds of carbohydrate chips. Clearly, the results show that the predicted lectin selectively binds to the carbohydrates, which demonstrates the applicability of the approach. Furthermore, the kinetics of the interactions between Con A and mannose, WGA and N-Acetylglucosamine were studied, respectively. This study provides an efficient approach to preparing carbohydrate chips based on PDA for the lectin–carbohydrate interactions study.

scholarly journals QCM Biosensor Based on Polydopamine Surface for Real-Time Analysis of the Binding Kinetics of Protein-Protein Interactions

Polymers ◽  
2017 ◽  
Vol 9 (12) ◽  
pp. 482 ◽  
Author(s):  
Chunli Wu ◽  
Xueming Li ◽  
Siyu Song ◽  
Yuxin Pei ◽  
Lili Guo ◽  
...  
Keyword(s):  
Real Time ◽  
Protein Interactions ◽  
Binding Kinetics ◽  
Protein Protein Interactions ◽  
Time Analysis ◽  
Real Time Analysis ◽  
Kinetics Of

scholarly journals Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting

2016 ◽  
Vol 9 ◽  
pp. 23-30 ◽  
Author(s):  
Thomas Mandel Clausen ◽  
Marina Ayres Pereira ◽  
Htoo Zarni Oo ◽  
Mafalda Resende ◽  
Tobias Gustavson ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Real Time ◽  
Binding Kinetics ◽  
Cancer Tissue ◽  
Primary Cancer ◽  
Label Free ◽  
Tissue Specimens

First LWD Co-Located Antenna Sensors for Real-Time Anisotropy and Dip Angle Determination, Yielding Better Look-Ahead Detection

2021 ◽  
Vol 62 (3) ◽  
pp. 296-310
Author(s):  
Michael Bittar ◽  
◽  
Hsu-Hsiang (Mark) Wu ◽  
Jin Ma ◽  
Li Pan ◽  
...  
Keyword(s):  
Real Time ◽  
Mapping Technique ◽  
Processing Scheme ◽  
Antenna Structure ◽  
Reliable Determination ◽  
Bedding Planes ◽  
Look Ahead ◽  
Hydrocarbon Saturation ◽  
Dip Angle

Electromagnetic (EM) resistivity tools measure the electrical properties of downhole formations that are critical in determining the hydrocarbon saturation of a reservoir. In complex and heterogeneous reservoirs, both horizontal and vertical formation resistivities are required to obtain an accurate hydrocarbon saturation. For decades, wireline multicomponent induction type measurements have provided reliable determination of formation anisotropy, structural dip, and dip azimuth in wells with any orientation relative to the bedding planes. Logging-while-drilling (LWD) multi-array propagation resistivity tools have also demonstrated similar capability in deviated wells where the relative dip angle is between 45° and 90°. However, measuring anisotropy and dip in wells with a low relative dip angle still poses difficulties for LWD propagation resistivity systems because of the antenna structures employed. This paper describes the development of a new LWD EM sensor equipped with an innovative, co-located, tilted antenna structure. The tool, along with a unique processing scheme, enables the determination of horizontal and vertical resistivity as well as the dip angle and the azimuth of the formation based on an assumption of transversely isotropic (TI) formation models (Graciet and Shen, 1998) while drilling in real time. The co-located sensor design is capable of acquiring multicomponent signals that are sensitive to formation anisotropy and structural dip in wells at any orientation. Modeling studies and several field trials have proven that the design concept can detect these formation properties at any arbitrary wellbore deviation. This paper presents test results from the new technology, together with reference measurements from azimuthally compensated LWD and fully triaxial wireline resistivity measurements. A good comparison is observed in these trials, providing an independent verification of the tool performance. The azimuthal measurements of the new sensors allow for determining formation anisotropy and dip at any wellbore deviation (Bittar et al., 2011b; Bittar et al., 2012), as well as providing 360° azimuthal resistivity and geosignals and allowing a three-dimensional (3D) resistivity mapping technique for real-time decisions. Integrating the co-located antennas with deep-reading antennas in a near-bit collar further provides both anisotropy measurements and ultradeep signals very close to the bit and enhances look-ahead detection ranges for LWD applications.

Real-time determination of kinetics of adsorption of lead(II) onto palm shell-based activated carbon using ion selective electrode

2008 ◽  
Vol 99 (13) ◽  
pp. 5786-5792 ◽  
Author(s):  
Mohamed Kheireddine Aroua ◽  
S.P.P. Leong ◽  
L.Y. Teo ◽  
Chun Yang Yin ◽  
Wan Mohd Ashri Wan Daud
Keyword(s):  
Activated Carbon ◽  
Real Time ◽  
Ion Selective Electrode ◽  
Selective Electrode ◽  
Kinetics Of Adsorption ◽  
Palm Shell ◽  
Time Determination ◽  
Kinetics Of

scholarly journals An electricity-fluorescence double-checking biosensor based on graphene for detection of binding kinetics of DNA hybridization

RSC Advances ◽  
2017 ◽  
Vol 7 (70) ◽  
pp. 44559-44567 ◽  
Author(s):  
Weiwei Yue ◽  
Caiyan Tang ◽  
Chunxing Wang ◽  
Chengjie Bai ◽  
Shuyi Liu ◽  
...  
Keyword(s):  
Dna Hybridization ◽  
Binding Kinetics ◽  
Kinetics Of

In this paper, an electricity-fluorescence double-checking biosensor based on graphene materials has been presented for detection of DNA hybridization kinetics.

Sign in / Sign up

Export Citation Format

Share Document