scholarly journals Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4

2012 ◽  
Vol 44 (11) ◽  
pp. 1231-1235 ◽  
Author(s):  
Jianfeng Xu ◽  
Zengnan Mo ◽  
Dingwei Ye ◽  
Meilin Wang ◽  
Fang Liu ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Prostate Cancer Risk ◽  
Genome Wide Association ◽  
Chinese Men ◽  
Genome Wide

scholarly journals Evaluation of reported prostate cancer risk-associated SNPs from genome-wide association studies of various racial populations in Chinese men

The Prostate ◽  
2013 ◽  
Vol 73 (15) ◽  
pp. 1623-1635 ◽  
Author(s):  
Rong Na ◽  
Fang Liu ◽  
Penyin Zhang ◽  
Dingwei Ye ◽  
Chuanliang Xu ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Association Studies ◽  
Prostate Cancer Risk ◽  
Genome Wide Association ◽  
Genome Wide Association Studies ◽  
Chinese Men ◽  
Genome Wide

Abstract 826: Large-scale genome-wide association study identifies multiple novel germline susceptibility variants associated with bladder cancer risk

2021 ◽  
Author(s):  
Stella Koutros ◽  
Lambertus A. Kiemeney ◽  
Roger L. Milne ◽  
Yuanqing Ye ◽  
Vijai Joseph ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Risk ◽  
Association Study ◽  
Large Scale ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Bladder Cancer Risk ◽  
Genome Wide

scholarly journals Multi-trait genome-wide association study identifies novel endometrial cancer risk loci that are associated with obesity or female testosterone levels

2021 ◽  
Author(s):  
Xuemin Wang ◽  
Pik Fang Kho ◽  
Dhanya Ramachandran ◽  
Cemsel Bafligil ◽  
Frederic Amant ◽  
...  
Keyword(s):  
Risk Factors ◽  
Endometrial Cancer ◽  
Cancer Risk ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Cancer Susceptibility ◽  
Genome Wide Association ◽  
Endometrial Cancer Risk ◽  
Cancer Risk Factors ◽  
Genome Wide

We have performed genetic correlation and Mendelian randomization analyses using publicly available genome-wide association study (GWAS) data to identify endometrial cancer risk factors. These and previously established risk factors of endometrial cancer were then included in a multi-trait Bayesian GWAS analysis to detect endometrial cancer susceptibility variants, identifying three novel loci (7q22.1, 8q24.3 and 16q12.2); two of which were replicated in an independent endometrial cancer GWAS dataset. These loci are hypothesized to affect endometrial cancer risk through altered sex-hormone levels or through effects on obesity. Consistent with this hypothesis, several genes with established roles in these pathways (CYP11B1, CYP3A7, IRX3 and IRX5) were prioritized as candidate endometrial cancer risk genes by interrogation of quantitative trait loci data and chromatin capture assays in endometrial cell lines. The findings of this study identify additional opportunities for hormone treatment and further support weight loss to reduce the risk of developing endometrial cancer.

Abstract LB-448: Genome-wide association study identifies new prostate cancer susceptibility loci

2011 ◽  
Author(s):  
Fredrick R. Schumacher ◽  
Sonja I. Berndt ◽  
Afshan Siddiq ◽  
Kevin Jacobs ◽  
Zhaoming Wang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Cancer Susceptibility ◽  
Genome Wide Association ◽  
Susceptibility Loci ◽  
Prostate Cancer Susceptibility ◽  
Genome Wide

scholarly journals Erratum: Corrigendum: Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Sara Lindström ◽  
Deborah J. Thompson ◽  
Andrew D. Paterson ◽  
Jingmei Li ◽  
Gretchen L. Gierach ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Association Study ◽  
Mammographic Density ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Multiple Loci ◽  
Genome Wide
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