Characterization of the blood pressure response during cycle ergometer cardiopulmonary exercise testing in black and white men

Abstract Background This study investigated the association between the blood pressure response during hemodialysis (HD) and exercise tolerance or heart rate recovery (HRR) measured with cardiopulmonary exercise testing (CPX). Methods The study enrolled 23 patients who had been undergoing 4-h regular maintenance HD. The maximum workload (Loadpeak), peak oxygen uptake (VO2peak), workload and oxygen uptake at the anaerobic threshold (LoadAT and VO2AT, respectively), and HRR were measured with CPX. The average systolic blood pressure during HD (SBPav) was measured, and the number of times the SBP was less than 100 mmHg was determined in the 2-week period after CPX. Results The SBPav showed a significant correlation with LoadAT (r = 0.46) and Loadpeak (r = 0.43, p < 0.05). The number of times the SBP was less than 100 mmHg showed a significant correlation with the HRR (r = − 0.44, p < 0.05). Conclusion Exercise intolerance and HRR in HD patients may be associated with blood pressure instability during HD.

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Abstract 13065: Blood Pressure Response to Treadmill Cardiopulmonary Exercise Testing in Children With Normal Hearts

Circulation ◽

10.1161/circ.142.suppl_3.13065 ◽

2020 ◽

Vol 142 (Suppl_3) ◽

Author(s):

Takeshi Sasaki ◽

Yuki Kawasaki ◽

Daiji Takajo ◽

Robert D Ross ◽

Daisuke Kobayashi

Keyword(s):

Blood Pressure ◽

Reference Values ◽

Blood Pressure Response ◽

Cardiopulmonary Exercise Testing ◽

Multiple Linear Regression Model ◽

Pressure Response ◽

Gender Effects ◽

Age And Gender ◽

Cardiopulmonary Exercise ◽

And Gender

Background: Blood pressure (BP) response to the treadmill cardiopulmonary exercise test (CPET) has yet been studied with no standard criteria for abnormal BP responses in children. Our hypothesis was that the reference values of BP responses to the treadmill CPET should be defined by gender and age in children. Objectives: The objective of our study was to describe the BP responses to the treadmill CPET and propose the criteria for abnormal BP responses in children. Methods: The treadmill CPET data were retrospectively analyzed to evaluate the BP responses to exercise during the period of 8 years (2011-2018). Children aged <18 years with normal hearts were included for the analysis. Results: Our cohort consisted of 1,085 children (males 59%) aged 7-17 years. The analysis of variance for Systolic BP at peak exercise (peak SBP) and change (Δ) of SBP showed significant age and gender effects and age-gender interaction effect ( p <0.01). In the multiple linear regression model ( p <0.001), peak SBP (mmHg) was predicted as 100.39 + 4.68 x age (years) for males; 132.27 + 1.37 x age (years) for females. The following criteria for abnormal BP responses in children were proposed. Hypertensive BP response were defined by peak SBP >90% confidence interval upper limit of reference values based on age and gender. Blunted BP response was defined by 1) ΔSBP <10 mmHg for age 7-11 years and <20 mmHg for age 12-17 years in males; and ΔSBP <10 mmHg in females. Conclusion: Blood Pressure response to the treadmill CPET was dependent on age and gender in children with normal hearts. The proposed criteria for abnormal BP responses in children should prove useful in interpreting BP responses in children during the CPET.

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