Comprehensive cardiac evaluation to maximal exercise in a contemporary population of prepubertal children

Purpose: Minimally invasive repair of pectus excavatum (MIRPE) was first reported in 1998 by D. Nuss. This technique has gained wide acceptance during the last 4-5 years. In the meantime, some modifications of the technique have been introduced by different authors. Our retrospective study reports our own experience over the last 36 months and modifications introduced due to a number of complications. Methods: From 3/2000 to 3/2003, 22 patients underwent MIRPE. Patients median age was 15.5 years (10.7 to 20.3 years). Standardised preoperative evaluation included 3D computerised tomography (CT) scan, pulmonary function tests, cardiac evaluation with electrocardiogram and echocardiography, and photo documentation. Indications for operation included at least two of the following: Haller CT index > 3.2, restrictive lung disease, cardiac compression, progression of the deformity and severe psychological alterations. Results: In 22 patients (2 girls, 20 boys) undergoing MIRPE procedure, a single bar was used in 21 patients and two bars in one boy. Lateral stabilisers were fixed with non resorbable sutures on both sides. Overall, postoperative complications occurred in six patients (27.3%). In two patients (9.1%) a redo-procedure was necessary due to bar displacement. An additional median skin incision was performed in two patients to elevate the sternum. Pneumothorax or hematothorax in two patients resulted in routine use of a chest tube on both sides. Long-term favourable results were noted in all patients. Conclusions: The MIRPE procedure is an effective method with elegant cosmetic results. Modifications of the original method help to decrease the complication rate and to accelerate acquirement of expertise.

Download Full-text

P391 Changes in QRS duration during exercise are associated with maximal exercise capacity and peak oxygen consumption in adults with repaired tetralogy of Fallot

European Heart Journal ◽

10.1016/s0195-668x(03)93829-2 ◽

2003 ◽

Vol 24 (5) ◽

pp. 49

Author(s):

W BUDTS

Keyword(s):

Oxygen Consumption ◽

Tetralogy Of Fallot ◽

Exercise Capacity ◽

Maximal Exercise ◽

Peak Oxygen Consumption ◽

Repaired Tetralogy Of Fallot ◽

Qrs Duration ◽

Maximal Exercise Capacity

Download Full-text

Magnetic resonance imaging and PV loop analysis for cardiac evaluation in small mice. A comparative analysis

The Thoracic and Cardiovascular Surgeon ◽

10.1055/s-0030-1268965 ◽

2011 ◽

Vol 59 (S 01) ◽

Author(s):

A Martens ◽

SV Rojas ◽

C Rathert ◽

I Gruh ◽

C Mauritz ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Comparative Analysis ◽

Magnetic Resonance ◽

Resonance Imaging ◽

Loop Analysis ◽

Cardiac Evaluation

Download Full-text

Radioiodine Uptake Values in Euthyroid, Non-Goitrous, Prepubertal Children in Greece

Nuklearmedizin ◽

10.1055/s-0038-1624805 ◽

1973 ◽

Vol 12 (01) ◽

pp. 26-34

Author(s):

D. Liakakos ◽

D. Ikkos ◽

P. Vlachos ◽

S. Gonticas ◽

P. Matsioulas ◽

...

Keyword(s):

Radioiodine Uptake ◽

Prepubertal Children

La fixation thyroïdienne du 131I a été mesurée en 50 enfants non-goitreux agés de 2 à 12 ans (17 masculins, 33 féminins). Les valeurs de fixation des enfants grèques (l’erreur standard ± pour les deux sexes était 38,8 ± 1,81; 59,1 ± 2,17; 60,2 ± 2,16 à 3, 24 et 48 heures) sont les plus élevées rapportées jusqu’à maintenant das la litérature donnant preuve à la pénurie de l’iode dans notre pays. Une autre manifestation de la pénurie de l’iode était l’observation, que dans 41% des enfants prépubertaires les valeurs PB 131I à 48 heures étaient plus élevées que la limite supérieure normale de 0,4% par litre.Les enfants féminines montraient des valeurs de fixation significativement (P < 0,05) plus élevées que les masculins avec un taux de différence des valeurs moyennes de 1,34; 1,19; et 1,15 à 3, 24 et 48 heures.

Download Full-text

Physical Exercise Induces Enhancement of Urokinase-Type Plasminogen Activator (u-PA) Levels in Plasma

Thrombosis and Haemostasis ◽

10.1055/s-0038-1647459 ◽

1991 ◽

Vol 65 (01) ◽

pp. 082-086 ◽

Cited By ~ 24

Author(s):

G Dooijewaard ◽

A de Boer ◽

P N C Turion ◽

A F Cohen ◽

D D Breimer ◽

...

Keyword(s):

Physical Exercise ◽

Plasminogen Activator ◽

Maximal Exercise ◽

Normal Values ◽

Bicycle Ergometer ◽

Tissue Type ◽

Healthy Male ◽

Type Plasminogen Activator ◽

Urokinase Type Plasminogen Activator ◽

Fibrinolytic Potential

SummaryThe enhancement of the blood fibrinolytic potential by physical exercise is generally attributed to the release of tissue-type plasminogen activator (t-PA) from the vessel wall. In this study we have investigated the possible contribution of urokinase-type plasminogen activator (u-PA).Six healthy male volunteers (age 21–25 years) were screened for their ability to perform maximal exercise for their age-group for 12 min on a bicycle ergometer. Subsequently, on one occasion they were required to remain supine for 2 h (from 8.30 a. m. onwards) and on another they performed maximal exercise (from 9.00 a.m. onwards). During exercise an increase in u-PA antigen and plasmin-activatable pro-urokinase (proUK) activity, concurrent with t-PA antigen and euglobulin t-PA activity, was observed in all six volunteers, while at rest these parameters remained unaffected. Mean u-PA- and t-PA antigen increased, respectively, from 4.2 ± 1.0 ng/ml and 5.8 ± 2.1 ng/ml before exercise to 9.8 ± 3.0 ng/ml and 18.3 ± 3.8 ng/ml (peak). Mean plasminactivatable proUK activity and t-PA activity increased, respectively, from 2.1 ± 0.4 ng/ml and 0.3 ± 0.2 ng/ml before exercise to 4.3 ± 1.7 ng/ml and 7.2 ± 4.0 ng/ml (peak). The increases were statistically significant throughout (paired t-test, pre vs post, antigen P <0.005 and activity P <0.02). After cessation of exercise u-PA and t-PA declined concurrently to normal values with a 50"/" decay in about 5 min. In conclusion, we found that both u-PA antigen and plasmin-activatable proUK activity are, concurrently with t-PA, enhanced upon exercise and, therefore, we consider that u-PA also contributes to – and co-operates in – the enhancement of the blood fibrinolytic potential and activity under these conditions.

Download Full-text