scholarly journals Exposure of Methicillin-Resistant Staphylococcus aureus to Low Levels of the Antibacterial THAM-3ΦG Generates a Small Colony Drug-Resistant Phenotype

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Alan J. Weaver ◽  
Tami R. Peters ◽  
Brian Tripet ◽  
Abigail Van Vuren ◽  
Rakesh ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Drug Resistant ◽  
Methicillin Resistant ◽  
Resistant Phenotype ◽  
Small Colony ◽  
Low Levels ◽  
Drug Resistant Phenotype

scholarly journals Antibacterial activity of Taxodium ascendens Diterpenes against Methicillin-resistant Staphylococcus aureus

2014 ◽  
Vol 9 (8) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Courtney M. Starks ◽  
Vanessa L. Norman ◽  
Russell B. Williams ◽  
Matt G. Goering ◽  
Stephanie M. Rice ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Bacterial Infections ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Clinical Isolates ◽  
Drug Resistant ◽  
Methicillin Resistant

One new and seven known diterpenes were identified from an antibacterial chromatographic fraction of Taxodium ascendens. Of these, demethylcryptojaponol (2), 6-hydroxysalvinolone (3), hydroxyferruginol (4), and hinokiol (5) demonstrated potent activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA). These compounds represent a class of synthetically accessible compounds that could be further developed for treatment of drug-resistant bacterial infections.

scholarly journals Novel organophosphorus aminopyrimidines as unique structural DNA-targeting membrane active inhibitors towards drug-resistant methicillin-resistant Staphylococcus aureus

MedChemComm ◽  
2018 ◽  
Vol 9 (9) ◽  
pp. 1529-1537 ◽  
Author(s):  
Di Li ◽  
Rammohan R. Yadav Bheemanaboina ◽  
Narsaiah Battini ◽  
Vijai Kumar Reddy Tangadanchu ◽  
Xian-Fu Fang ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Molecular Modeling ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Antibacterial Mechanism ◽  
Drug Resistant ◽  
Methicillin Resistant ◽  
Dna Targeting

Molecular modeling of organophosphorus aminopyrimidine and the possible antibacterial mechanism.

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