Abstract
Background: Depression and sarcopenia are common diseases in the elderly population. However, the association between them is controversial. Based on the Chinese Longitudinal Healthy Longevity Survey (CLHLS) database, a cross-sectional study was conducted to explore the relationship between calf circumference, physical performance, and depression.Methods: From the 8th wave of CLHLS conducted in 2018, data on calf circumference, physical performance, depressive symptoms, and demographic, socioeconomic, and health-related characteristics were collected. A statistical analysis was conducted to explore the relationship between calf circumference, physical performance, and depressive symptoms. Confounding factors were adjusted for in the multiple logistic regression analysis.Results: A total of 12,227 participants, including 5689 (46.5%) men and 6538 (53.5%) women (mean age, 83.4 years), were included in this study. After adjusting for confounding factors, the association between calf circumference and depression disappeared (odds ratio [OR] = 1.04, 95% confidence interval [CI]: 0.92–1.17, p = 0.58). However, a significant inverse correlation persisted between physical performance and depressive symptoms (OR = 1.16, 95% CI: 1.13–1.20, p＜0.001). The subgroup analysis revealed a significant association of calf circumference (OR = 1.3, 95% CI: 1.04–1.62, p = 0.02) and physical performance (OR = 1.15, 95% CI: 1.08–1.22, p < 0.001) with depression in the regular exercise group.Conclusions: Physical performance was significantly associated with depression in the elderly Chinese population. Attention should be paid to assess depressive symptoms in patients with poor muscle condition.
The relationship between Plasma Markers and Essential Hypertension in Middle-aged and Elderly Chinese Population: A Community Based Cross-sectional Study
