Association Among Calf Circumference, Physical Performance, and Depression in the Elderly Chinese Population: A Cross-Sectional Study

Abstract Background: Depression and sarcopenia are common diseases in the elderly population. However, the association between them is controversial. Based on the Chinese Longitudinal Healthy Longevity Survey (CLHLS) database, a cross-sectional study was conducted to explore the relationship between calf circumference, physical performance, and depression.Methods: From the 8th wave of CLHLS conducted in 2018, data on calf circumference, physical performance, depressive symptoms, and demographic, socioeconomic, and health-related characteristics were collected. A statistical analysis was conducted to explore the relationship between calf circumference, physical performance, and depressive symptoms. Confounding factors were adjusted for in the multiple logistic regression analysis.Results: A total of 12,227 participants, including 5689 (46.5%) men and 6538 (53.5%) women (mean age, 83.4 years), were included in this study. After adjusting for confounding factors, the association between calf circumference and depression disappeared (odds ratio [OR] = 1.04, 95% confidence interval [CI]: 0.92–1.17, p = 0.58). However, a significant inverse correlation persisted between physical performance and depressive symptoms (OR = 1.16, 95% CI: 1.13–1.20, p＜0.001). The subgroup analysis revealed a significant association of calf circumference (OR = 1.3, 95% CI: 1.04–1.62, p = 0.02) and physical performance (OR = 1.15, 95% CI: 1.08–1.22, p < 0.001) with depression in the regular exercise group.Conclusions: Physical performance was significantly associated with depression in the elderly Chinese population. Attention should be paid to assess depressive symptoms in patients with poor muscle condition.

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Association between depressive symptoms and arterial stiffness: a cross-sectional study in the general Chinese population

BMJ Open ◽

10.1136/bmjopen-2019-033408 ◽

2020 ◽

Vol 10 (2) ◽

pp. e033408 ◽

Cited By ~ 2

Author(s):

Liming Peng ◽

Sisi Bi ◽

Xiangwei Liu ◽

Tianyi Long ◽

Yixia Zhao ◽

...

Keyword(s):

Diabetes Mellitus ◽

Depressive Symptoms ◽

Arterial Stiffness ◽

Chinese Population ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Beta Coefficient ◽

The Relationship ◽

General Chinese Population

ObjectivesTo determine the independent relationship between depressive symptoms and arterial stiffness in the general Chinese population, and to explore possible interactive factors in the relationship.DesignA cross-sectional study.Setting and participantsConsecutive participants who received routine health physical examination in an affiliated hospital of a comprehensive university in Hunan Province, China, between September 2013 and March 2014 were examined. After exclusion of subjects not meeting the criteria, a total of 1334 subjects aged 22–77 years were recruited for final analysis.MeasuresThe Patient Health Questionnaire-9 was employed to assess the degree of depressive symptoms: 0–4 no depressive symptoms, 5–9 mild depressive symptoms and 10–27 moderate to severe depressive symptoms. Brachial-ankle pulse wave velocity (baPWV) was measured to determine arterial stiffness.ResultsThere was a slight increase in baPWV across elevated degrees of depressive symptoms (p=0.025). Multivariate linear regression analysis revealed that mild depressive symptoms and moderate to severe depressive symptoms were independently associated with baPWV compared with no depressive symptoms after adjusting for baseline confounders (beta-coefficient: 40.3, 95% CI 6.6 to 74.1; beta-coefficient: 87.7, 95% CI 24.0 to 151.5, respectively). Further stratified analyses indicated that the relationship between degree of depressive symptoms and baPWV was predominant in subjects who had normal or normal-high blood pressure, or combined with hypertension (p for interaction=0.016), or in subjects with diabetes mellitus (p for interaction=0.004), examined in multivariate linear regressions. In addition, after adjustment, a significant association between moderate to severe depressive symptoms and baPWV was also found in female subjects younger than 60 years, although the interactive effect was not significant (p for interaction=0.056).ConclusionsDepressive symptoms are independently associated with arterial stiffness, especially in subjects whose blood pressures are beyond the optimal range and combined with diabetes mellitus.

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Risk factors of acute pancreatitis in the elderly Chinese population: A population-based cross-sectional study

Journal of Digestive Diseases ◽

10.1111/1751-2980.12168 ◽

2014 ◽

Vol 15 (9) ◽

pp. 501-507 ◽

Cited By ~ 8

Author(s):

Hong Yang ◽

Li Wang ◽

Yi Hai Shi ◽

Guang Tao Sui ◽

Yun Fei Wu ◽

...

Keyword(s):

Risk Factors ◽

Acute Pancreatitis ◽

Chinese Population ◽

The Elderly ◽

Population Based ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Elderly Chinese

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High TG/HDL ratio suggests a higher risk of metabolic syndrome among an elderly Chinese population: a cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2020-041519 ◽

2021 ◽

Vol 11 (3) ◽

pp. e041519

Author(s):

Guqiao Nie ◽

Shukai Hou ◽

Meng Zhang ◽

Wen Peng

Keyword(s):

Metabolic Syndrome ◽

Physical Examination ◽

Chinese Population ◽

Elderly Population ◽

The Elderly ◽

Critical Value ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Elderly Chinese

ObjectivesTo investigate the relationship between triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio and metabolic syndrome in the elderly population of China, and to determine the best critical value of TG/HDL-C in higher risk of metabolic syndrome in this population.DesignCross-sectional study.SettingOur study was conducted in a community physical examination centre in Wuhan, China between 1 January 2016 and 31 December 2016.ParticipantsThe physical examination data from 1267 elderly people (aged over 65 years) in the community were analysed in this study. The average age of the study participants was 71.64±5.605 years.Primary outcome measuresCorrelation between the TG/HDL-C ratio and metabolic syndrome; the optimum cut-off of the TG/HDL-C ratio for the prediction of metabolic syndrome.ResultsThe TG/HDL-C ratio showed a significant positive correlation with metabolic syndrome (r=0.420, p<0.001) in the elderly Chinese population. Binary logistic regression analysis showed that the TG/HDL-C ratio was an independent risk factor for metabolic syndrome (OR=3.07 (95% CI: 2.402 to 3.924), p<0.001) after adjusting for blood pressure, blood glucose, age, sex and body mass index. The receiver operating characteristic curves of TG/HDL-C ratio and metabolic syndrome showed that in the elderly population, a TG/HDL-C ratio of 1.49 can be used as the critical value for a higher risk of metabolic syndrome. At this value, the specificity and sensitivity of the measure were optimal (80.8% and 72.4%, respectively).ConclusionIn this study, we found a significant correlation between TG/HDL-C ratio and metabolic syndrome. And high TG/HDL ratio suggests a higher risk of metabolic syndrome among an elderly Chinese population.

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The relationship between Plasma Markers and Essential Hypertension in Middle-aged and Elderly Chinese Population: A Community Based Cross-sectional Study

Scientific Reports ◽

10.1038/s41598-019-43278-4 ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 3

Author(s):

Tesfaldet Habtemariam Hidru ◽

Xiaolei Yang ◽

Yunlong Xia ◽

Li Ma ◽

Hui-Hua Li

Keyword(s):

Essential Hypertension ◽

Chinese Population ◽

Cross Sectional Study ◽

Sectional Study ◽

Middle Aged ◽

Community Based ◽

Cross Sectional ◽

Elderly Chinese ◽

The Relationship ◽

Plasma Markers

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Association of depressive symptoms with ambient PM2.5 in middle-aged and elderly Chinese adults: A cross-sectional study from the China health and Retirement Longitudinal Study wave 4

Environmental Research ◽

10.1016/j.envres.2021.111889 ◽

2022 ◽

Vol 203 ◽

pp. 111889

Author(s):

Yifan Yao ◽

Tianjun Lu ◽

Yisi Liu ◽

Qiujun Qin ◽

Jie Jiang ◽

...

Keyword(s):

Depressive Symptoms ◽

Longitudinal Study ◽

Cross Sectional Study ◽

Sectional Study ◽

Middle Aged ◽

Chinese Adults ◽

Cross Sectional ◽

Elderly Chinese

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Associations between residual depressive symptoms, cognition, and functioning in patients with euthymic bipolar disorder: results from the FACE-BD cohort

The British Journal of Psychiatry ◽

10.1192/bjp.bp.117.201335 ◽

2017 ◽

Vol 211 (6) ◽

pp. 381-387 ◽

Cited By ~ 18

Author(s):

Paul Roux ◽

Aurélie Raust ◽

Anne-Sophie Cannavo ◽

Valérie Aubin ◽

Bruno Aouizerate ◽

...

Keyword(s):

Bipolar Disorder ◽

Depressive Symptoms ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Cognitive Component ◽

Cognitive Components ◽

The Face ◽

Sources Of Variation ◽

The Relationship

BackgroundThe relationship between residual depressive symptoms, cognition and functioning in patients with euthymic bipolar disorder is a subject of debate.AimsTo assess whether cognition mediates the association between residual depressive symptoms and functioning in patients with bipolar disorder who were euthymic.MethodWe included 241 adults with euthymic bipolar disorder in a multicentre cross-sectional study. We used a battery of tests to assess six cognition domains. A path analysis was then used to perform a mediation analysis of the relationship between residual depressive symptoms, cognitive components and functioning.ResultsOnly verbal and working memory were significantly associated with better functioning. Residual depressive symptoms were associated with poorer functioning. No significant relationship was found between residual depressive symptoms and any cognitive component.ConclusionsCognition and residual depressive symptoms appear to be two independent sources of variation in the functioning of people with euthymic bipolar disorder.

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