scholarly journals Interaction effect of oxytocin receptor (OXTR) rs53576 genotype and maternal postpartum depression on child behavioural problems

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Damee Choi ◽  
Kenji J. Tsuchiya ◽  
Nori Takei
2021 ◽  
Vol 9 ◽  
pp. 205031212198949
Author(s):  
Wondimye Ashenafi ◽  
Bezatu Mengistie ◽  
Gudina Egata ◽  
Yemane Berhane

Background: Intimate partner violence during pregnancy is a strong predictor of maternal postpartum depression. In Ethiopia, evidence on the association of intimate partner violence during pregnancy with postpartum depression is very limited. To design appropriate intervention, it is thus important to understand how postpartum depression varies as a function of the type and severity of intimate partner violence victimization during pregnancy. The aim of this study is to explore the association of different types of intimate partner violence during pregnancy and its severity with postpartum depression in Eastern Ethiopia. Method: A community-based cross-sectional study was conducted from January to October 2018. The study included a sample of 3015 postpartum women residing in Eastern Ethiopia. The cutoff point for postpartum depression was defined as ⩾13 points according to the Edinburgh Postnatal Depression Scale. The prevalence ratio with 95% confidence intervals was calculated, and the association between the main predictor (i.e. intimate partner violence during pregnancy) and the outcome variable (postpartum depression) was determined using log binomial regression model. Results: 16.3% (95% confidence interval: 14.9–17.7) of women experienced postpartum depression. After controlling potential confounding factors, the prevalence of postpartum depression among women exposed to severe physical intimate partner violence during pregnancy was 1.98 times higher as compared to those not exposed to physical intimate partner violence during pregnancy (adjusted prevalence ratio = 1.98; 95% confidence interval: 1.53–2.54). Exposure to psychological intimate partner violence during pregnancy was found to increase the prevalence of postpartum depression by 1.79 as compared to non-exposure to psychological intimate partner violence during pregnancy (adjusted prevalence ratio = 1.79; 95% confidence interval: 1.48–2.18). Conclusion: The study provides evidence that psychological and severe physical intimate partner violence during pregnancy were significantly associated with maternal postpartum depression. Screening of pregnant women for intimate partner violence and providing them the necessary support can minimize the risk to postpartum depression.


2016 ◽  
Vol 1 (1) ◽  
pp. 175-181
Author(s):  
Nancy Hall

Objective To survey speech-language pathologists (SLPs) regarding their involvement in treating infants whose mothers experience postpartum depression. Method SIG 1 members were invited to participate in an 8-question survey examining their involvement with infant-mother pairs, including mothers diagnosed with postpartum depression (PPD). Results Results indicate that, while some SLPs frequently work with infant-mother pairs, few have knowledge regarding the diagnosis of PPD in the mothers. Conclusions It is likely that many SLPs are working with infant-mother pairs that include mothers who are experiencing PPD. Suggestions regarding the role of the SLP are offered, including providing support for these mothers in terms of obtaining services and helping these mothers use appropriate infant-directed speech to facilitate communication and cognitive development in their infants.


2012 ◽  
Vol 53 (2) ◽  
pp. 143-151 ◽  
Author(s):  
Monique Robinson ◽  
Andrew J.O. Whitehouse ◽  
Stephen R. Zubrick ◽  
Craig E. Pennell ◽  
Peter Jacoby ◽  
...  

2019 ◽  
Vol 71 (1) ◽  
pp. 159-165 ◽  
Author(s):  
Jelena Basic ◽  
Vuk Milosevic ◽  
Milos Stankovic ◽  
Tatjana Jevtovic-Stoimenov ◽  
Tatjana Cvetkovic ◽  
...  

Oxytocin achieves its effects after binding the oxytocin receptor (OXTR). Oxytocin plays an important role in empathy. The aim of this study was to examine the influence of two single nucleotide polymorphisms (SNPs) of the OXTR gene (rs53576 and rs2254298) on empathy measures and plasma oxytocin levels. Seventy-four university students were screened for the OXTR rs53576 and rs2254298 SNPs using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. The level of oxytocin in the plasma was measured by the enzyme linked immunosorbent assay (ELISA). All subjects were assessed with the empathy quotient (EQ) questionnaire and Reading the Mind in the Eyes Test (RMET). Subjects carrying the rs53576 GG genotype had a higher EQ score, compared to GA/AA genotype carriers. By gender analysis, significance was reached only in females. Considering the influence of both examined polymorphisms on empathy, participants with the GGGG diplotype had a higher EQ in comparison with GAGG/AAGG carriers. These hormone effects were not correlated with plasma oxytocin levels. This is the first study implying that higher empathy in rs53576 GG genotype carriers may not depend on plasma oxytocin levels, but possibly on the number and function of OXTRs in the brain.


2020 ◽  
Author(s):  
Alessandro Carollo ◽  
Andrea Bonassi ◽  
Ilaria Cataldo ◽  
Giulio Gabrieli ◽  
Moses Tandiono ◽  
...  

So far literature considered the association between environmental factors (i.e. involved in adult relationships) and genetic vulnerability on Oxytocin Receptor Gene (OXTR) in the comprehension of social behavior. Although an extensive knowledge on in-person social interactions has been obtained, little is known about online social behavior. A gene-environment perspective is adopted to examine how OXTR and adult attachment moderate Instagram behavior. The Experience in Close Relationships-Revised (ECR-R) questionnaire was used to collect participants' (N = 57, 16 males) attachment with their partners. The genetic factors within the regions OXTR rs53576 (A/A homozygotes vs. G-carriers) and rs2254298 (G/G homozygotes vs. A-carriers) were assessed. Number of posts, followed people ("followings") and followers were obtained from Instagram, and the Social Desirability Index was calculated as the ratio of followers to followings. Interaction effects between OXTR groups and ECR-R scores on the number of posts and SDI were hypothesised. Results showed an effect of rs53576 on the number of Instagram followings. Specifically, A/A homozygotes had more followings than G-carriers independently of the quality of the relationship with their partner. These preliminary results are discussed in light of the debate of behavioral genetics and offer insights into future investigations on social media behavior.


2010 ◽  
Vol 38 (1) ◽  
pp. 8-16 ◽  
Author(s):  
Donna Demetri Friedman ◽  
Beatrice Beebe ◽  
Joseph Jaffe ◽  
Don Ross ◽  
Sandra Triggs

2018 ◽  
Vol 62 (4) ◽  
pp. 420-439 ◽  
Author(s):  
Till Kaiser ◽  
Jianghong Li ◽  
Matthias Pollmann-Schult

The strong link between parental socioeconomic status (SES) and children’s success in school is well established. However, mechanisms that underpin this association remain a major issue in current research on social inequality. Using data from the Families in Germany Study and structural equation modelling, this study demonstrates that parenting styles and child behavioural problems explain, in part, the association between parental SES and child school grades for mathematics and German between the ages of 9 and 10. We found that parents with a low SES are more likely to be inconsistent in their parenting and to use psychological control with their children more often, these two factors being linked to child behavioural problems. Adverse parenting and behavioural problems are, in turn, associated with low school grades. Our findings also show that behavioural problems in children are associated with lower school grades independent of parenting style. These findings suggest that parenting styles and child behavioural problems and their interplay may be potential pathways that underpin the influence of parental SES on children’s school achievement.


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