scholarly journals The contribution of ocular residual astigmatism to anterior corneal astigmatism in refractive astigmatism eyes

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jian Lin
Keyword(s):  
Correlation Analysis ◽  
Interquartile Range ◽  
Corneal Astigmatism ◽  
Vector Analysis ◽  
Spearman Correlation ◽  
Inclusion Criteria ◽  
Ocular Residual Astigmatism ◽  
Anterior Corneal Astigmatism ◽  
Superimposed Effect

AbstractTo determine the distribution of ocular residual astigmatism (ORA) in astigmatic eyes and the influence on the anterior corneal (ACA) and refractive astigmatism (RA). A total of 165 children met the inclusion criteria. Right eyes’ data were analyzed. Using Thibos vector analysis to calculate ORA. Spearman correlation analysis was used to obtain the correlation between the magnitude of ORA, ACA and RA. The median magnitude of ORA in astigmatic eyes was 0.57 D, with interquartile range was 0.42 D. And they were main against-the-rule (57.6–75.8%) and oblique astigmatism (13.9–34.5%) ORA. The ORA in 140 eyes (84.8%) acted as an offset to ACA, meanwhile, 25 eyes (15.2%) superimposed it. About 98% (97.9–98.4%) against-the-rule and 75% (73.9–82.5%) oblique ORA counteracted ACA, nevertheless, all with-the-rule ORA had a superimposed effect on ACA. For with-the-rule ACA, about 86% (85.4–85.9%) ORA worked to offset it. There was statistically correlations between ORA and ACA (r = 0.17, P = 0.03), ORA and RA (r = − 0.27, P = 0.001). The magnitude of ocular residual astigmatism was relatively small in children’s astigmatic eyes. Both against-the-rule and oblique ORA can counteract with-the-rule ACA.

scholarly journals Impact of Ocular Residual Astigmatism On Anterior Corneal Astigmatism In Children With Low And Moderate Myopia

2021 ◽  
Author(s):  
Jian Lin ◽  
Dexiang An ◽  
Yun Lu ◽  
Dongmei Yan
Keyword(s):  
Correlation Analysis ◽  
Physical Method ◽  
Corneal Astigmatism ◽  
Moderate Correlation ◽  
Ocular Residual Astigmatism ◽  
Manifest Refraction ◽  
The Mean ◽  
The Relationship ◽  
Anterior Corneal Astigmatism

Abstract Background: To assess the influence of ocular residual astigmatism to anterior corneal astigmatism in children with low and moderate myopia.Methods: Refractive astigmatism was obtained by subjective manifest refraction. Anterior corneal astigmatism was obtained by IOL Master. Using Thibos vector analysis to calculate ocular residual astigmatism. Correlation analysis was used to assess the relationship between the magnitude of ocular residual astigmatism and anterior corneal astigmatism. The influence of ocular residual astigmatism to anterior corneal astigmatism was evaluated by Physical method.Results: The study analyzed 241 right eyes of 241 children aged 8 to 18 years old. In this study, the median magnitude of ocular residual astigmatism was 1.02 D, with interquartile range was 0.58 D. Against-the-rule ocular residual astigmatism was seen in 232 eyes (96.3%). There was a significant and moderate correlation between ocular residual astigmatism and anterior corneal astigmatism (r = 0.50, P < 0.001). The ocular residual astigmatism in 240 eyes (99.6%) had a compensatory effects on anterior corneal astigmatism. The mean compensation value was 1.00 ± 0.41 D (rang 0.02 D to 2.34 D). Based on this effect, 37 eyes had different axial classification of anterior corneal astigmatism and refractive astigmatism. By contrast, one eye (0.4%) had oblique ocular residual astigmatism and superimposed with-the-rule anterior corneal astigmatism.Conclusions: The magnitude of ocular residual astigmatism was relatively huge in myopia children and predominantly compensated anterior corneal astigmatism. The ocular residual astigmatism should be assessed first before fitting orthokeratology.

scholarly journals Contribution of Ocular Residual Astigmatism to Anterior Corneal Astigmatism in Children with Low and Moderate Myopia

2021 ◽  
Author(s):  
Jian Lin ◽  
Dexiang An ◽  
Yun Lu ◽  
Dongmei Yan ◽  
Leilei Wang
Keyword(s):  
Correlation Analysis ◽  
Physical Method ◽  
Corneal Astigmatism ◽  
Moderate Correlation ◽  
Ocular Residual Astigmatism ◽  
Manifest Refraction ◽  
The Mean ◽  
The Relationship ◽  
Anterior Corneal Astigmatism

Abstract To assess the contribution of ocular residual astigmatism (ORA) to anterior corneal astigmatism (ACA) in children with low and moderate myopia. Refractive astigmatism (RA) were received by subjective manifest refraction. ACA were obtained by IOL Master. Using Thibos vector analysis to calculate ORA. Correlation analysis was used to assess the relationship between the magnitude of ORA and ACA. The contribution of ORA to ACA was evaluated by Physical method. The study analyzed 241 right eyes of 241 children aged 8 to 18 years old. In this study, the median magnitude of ORA was 1.02 D, with interquartile range was 0.58 D. Against-the-rule ORA was seen in 232 eyes (96.3%). There was a significant and moderate correlation between ORA and ACA (r = 0.50, P < 0.001). The ORA in 240 eyes (99.6%) had a compensatory effects on ACA. The mean compensation value was 1.00 ± 0.41 D. Based on this effect, 37 eyes had different axial classification of ACA and RA. By contrast, one eye (0.4%) had oblique ORA and superimposed with-the-rule ACA. The magnitude of ORA was relatively huge in myopia children and predominantly compensated ACA. The ORA should be assessed first before fitting orthokeratology.

Targeting Anterior Corneal Astigmatism With Topography-Guided Ablation Ignores Ocular Residual Astigmatism, Resulting in Inferior Outcomes

2020 ◽  
Vol 36 (1) ◽  
pp. 63-64
Author(s):  
Avi Wallerstein ◽  
Mathieu Gauvin ◽  
Mark Cohen ◽  
Kemal Ozulken ◽  
Manoj Motwani ◽  
...  
Keyword(s):  
Corneal Astigmatism ◽  
Ocular Residual Astigmatism ◽  
Anterior Corneal Astigmatism

Expression Levels of MicroRNA-125b in Serum Exosomes of Patients with Asthma of Different Severity and its Diagnostic Significance

2019 ◽  
Vol 20 (10) ◽  
pp. 781-784 ◽  
Author(s):  
Meizhen Zhao ◽  
Li Juanjuan ◽  
Fan Weijia ◽  
Xie Jing ◽  
Huang Qiuhua ◽  
...  
Keyword(s):  
Correlation Analysis ◽  
Roc Curve ◽  
Quantitative Polymerase Chain Reaction ◽  
Persistent Asthma ◽  
Asthma Severity ◽  
Control Group ◽  
Spearman Correlation ◽  
Diagnostic Efficacy ◽  
Expression Levels ◽  
Serum Exosomes

Background: This study aimed to investigate the expression levels of microRNA (miRNA)-125b in serum exosomes and its diagnostic efficacy for asthma severity. Methods: The study included 80 patients with untreated asthma and 80 healthy volunteers. The patients were divided into 4 groups according to disease severity: 20 with the intermittent state, 20 with the mildly persistent state, 20 with the moderately persistent state, and 20 with the severely persistent state. The expression levels of miRNA-125b in serum exosomes of each group were detected using a quantitative polymerase chain reaction and compared. The Spearman correlation analysis was used to study the correlation between the expression levels of miRNA-125b in serum exosomes and asthma severity. The diagnostic efficacy of the expression levels of miRNA-125b in exosomes for asthma severity was evaluated using the Receiver Operating Characteristic (ROC) curve. Results: The expression levels of miRNA-125b in serum exosomes of patients with intermittent, mildly persistent, moderately persistent, and severely persistent asthma were all higher than those in the healthy control group, with statistically significant differences. The expression levels of miRNA-125b were also statistically significantly different among patients in each group. The Spearman correlation analysis showed a positive correlation of the relative expression of miRNA-125b in serum exosomes with asthma severity. The area under the ROC curve of the diagnostic efficacy of miRNA-125b in serum exosomes for patients with intermittent, mildly, moderately, and severely persistent asthma was 0.7770, 0.8573, 0.9111, and 0.9995, respectively. Conclusion: The expression levels of miRNA-125b in serum exosomes had a high diagnostic efficacy and might serve as a noninvasive diagnostic marker for asthma severity.

scholarly journals Does pterygium morphology affect corneal astigmatism?

2021 ◽  
Vol 13 ◽  
pp. 251584142110304
Author(s):  
Emine Doğan ◽  
Burçin Çakır ◽  
Nilgün Aksoy ◽  
Elif Köse ◽  
Gürsoy Alagöz
Keyword(s):  
Anterior Segment ◽  
Clinical Information ◽  
Corneal Astigmatism ◽  
Continuous Group ◽  
Optic Coherence Tomography ◽  
Morphological Pattern ◽  
Horizontal Length ◽  
The Mean ◽  
Anterior Corneal Astigmatism ◽  
Posterior Corneal Astigmatism

Purpose: The purpose of this study was to evaluate the correlation between corneal astigmatism and the morphology of pterygium with anterior segment optic coherence tomography (AS-OCT). Material and Methods: The size of pterygium (horizontal length, vertical width) was measured manually; pterygium area and percentage extension of the pterygium onto the cornea were calculated. Anterior and posterior corneal astigmatism, Sim K, K1, K2 were measured using a dual Scheimpflug analyzer. Morphological patterns of the pterygium analyzed with AS-OCT were determined according to the extension of the pterygium apex below the corneal epithelium. Two tomographic patterns were identified: continuous and nodular. Correlation between anterior corneal astigmatism and pterygium size, percentage extension of the pterygium, and morphological pattern of the pterygium was analyzed. Results: The mean ages of the 47 patients were 49.4 ± 16.6 (22–80) years. Mean horizontal pterygium length, vertical width, pterygium area, and percentage extension of the pterygium were 2.8 ± 1.2 mm, 4.8 ± 1.6 mm, 7.42 ± 5.6 mm2 and 24.5 ± 10.4%, respectively. Mean anterior corneal astigmatism was 2.3 ± 2.3 D and simulated keratometry was 43.4 ± 2.02 D. In terms of the morphological pattern of the pterygium, 24 eyes had continuous, 23 eyes had a nodular pattern and the median (interquartile range) anterior corneal astigmatism was 1.87 (1.01–3.80) and 1.22 D (0.58–2.35), respectively ( p = 0.102). Other topographic and pterygium size parameters were similar between groups. Analyzing the correlations in groups separately, a positive moderate statistically significant correlation was present between vertical width, percentage extension, pterygium area, and anterior corneal astigmatism in both continuous and nodular groups. Conclusions: Although not statistically significant, anterior corneal astigmatism was higher in continuous group. Using AS-OCT to standardize the morphology of pterygium could provide additional clinical information.

Power Vector Analysis of Corneal Astigmatism among Chinese over Fifty Years Old: a retrospective cross-sectional study

2020 ◽  
Author(s):  
Yilin Pang ◽  
Xiaoguang Cao ◽  
Xianru Hou ◽  
Li Yuan ◽  
Yongzhen Bao
Keyword(s):  
Axial Length ◽  
Linear Trend ◽  
Linear Regression Analysis ◽  
Corneal Astigmatism ◽  
Vector Analysis ◽  
Cross Sectional ◽  
Age Related ◽  
Relationship Of ◽  
The Relationship ◽  
Cataract Patients

Abstract Background: To investigate the relationship between corneal astigmatism and age, axial length (AL) among Chinese over fifty years old. Methods: This study enrolled 1,082 right eyes of age-related cataract patients over 50 years old in the clinic of Peking University People’s Hospital, Beijing, China. Axial length, magnitude and meridian of anterior corneal astigmatism were measured by IOLMaster. Restricted cubic splines and Spearman rank correlation coefficients were used to investigate the relationship of the magnitude of cornea astigmatism to age and AL. Power vector analysis method and linear regression analysis were used to assess the relationship of the meridian of astigmatism to age and AL. Results: For this study , mean age, AL, and corneal astigmatism value were 72.45 ±9.28 years, 23.90±1.93mm, and 1.12±0.74D, respectively. The magnitude of corneal astigmatism was 0.75D or higher in 63.8% eyes. The magnitude of corneal astigmatism increased with age after 65 years old. This correlation was statistically significant when AL was between 22.00mm and 26.00mm. The vector value in J 0 was inversely correlated with age. The mean vector value change from with-the-rule (WTR) to against-the-rule (ATR) corneal astigmatism was 0.22D/10 years during 50-65 years old and 0.15D/10 years during 65-85 years old, and was 0.22D/10 years in male and 0.12D/10 years in female, respectively. Conclusions: A large proportion of elderly Chinese cataract patients over 50 years old have corneal astigmatism more than 0.75D . There was a non-linear trend from WTR astigmatism towards ATR astigmatism with age, which was more obvious in elder age and in male. When AL is between 22.00mm and 26.00mm, the magnitude of corneal astigmatism increases with age after 65 years old.

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