Role of eccentricity in early Holocene African and Asian summer monsoons

The effect of precession on paleoclimate changes depends on eccentricity. However, whether and to what degree eccentricity relates to millennial-scale monsoonal changes remain unclear. By investigating climate simulations with a fixed precession condition of 9 ka before the present, we explored the potential influence of eccentricity on early-Holocene changes in the Afro–Asian summer monsoons. Compared with the lower eccentricity of the present day, higher eccentricity in the early Holocene strengthened the continental summer monsoons, Pacific anticyclone, and Hadley circulation, particularly over the ocean. Over Africa, the eccentricity-induced “dry-gets-wetter” condition could be related to the Green Sahara, suggesting a superimposed effect of precession. Over the western Pacific, the tropical response to eccentricity may have been competitive in terms of what an extremely high obliquity may have caused. A downscaled modulation of eccentricity in relation to precession and obliquity cannot be ignored when paleomonsoon records are studied. Regarding early-Holocene monsoonal changes in South Asia, however, a high eccentricity may have had only a secondary effect on enhancing the monsoonal precipitation in the southern edge of the Tibetan Plateau, exhibiting the weak power of candle-like heating. This suggested that sizable monsoonal changes over the northern Indian Ocean and India–Pakistan region are unrelated to early-Holocene eccentricity.

Rockburst Prediction on the Superimposed Effect of Excavation Accumulation Energy and Blasting Vibration Energy in Deep Roadway

In deep mining, much elastic energy is stored in rock mass due to the high geostress. Rockburst will be induced by accumulated energy during excavation. Meanwhile, because of blasting vibration energy in the host rock, there will be an obvious superimposed effect on the probability and intensity of rockburst. To explore the most reasonable and effective method for understanding rockburst problem under blasting, a deep roadway of Sanshandao gold mine was studied. On the basis of in situ geostress data, the accumulated energy of three-centered arch roadway after quasi-static excavation was derived. Then, a series of in situ blasting vibration were monitored, and the blasting vibration energy was calculated by employing the equivalent theory of elastic vibration boundary. Finally, the tendentiousness of rockburst was evaluated qualitatively with the superimposed energy. The results indicated that the disaster-driven energy was increased by 45.1% and 28.2% on different places of roadway. Also, the probability and intensity of rockburst would be raised.

The contribution of ocular residual astigmatism to anterior corneal astigmatism in refractive astigmatism eyes

To determine the distribution of ocular residual astigmatism (ORA) in astigmatic eyes and the influence on the anterior corneal (ACA) and refractive astigmatism (RA). A total of 165 children met the inclusion criteria. Right eyes’ data were analyzed. Using Thibos vector analysis to calculate ORA. Spearman correlation analysis was used to obtain the correlation between the magnitude of ORA, ACA and RA. The median magnitude of ORA in astigmatic eyes was 0.57 D, with interquartile range was 0.42 D. And they were main against-the-rule (57.6–75.8%) and oblique astigmatism (13.9–34.5%) ORA. The ORA in 140 eyes (84.8%) acted as an offset to ACA, meanwhile, 25 eyes (15.2%) superimposed it. About 98% (97.9–98.4%) against-the-rule and 75% (73.9–82.5%) oblique ORA counteracted ACA, nevertheless, all with-the-rule ORA had a superimposed effect on ACA. For with-the-rule ACA, about 86% (85.4–85.9%) ORA worked to offset it. There was statistically correlations between ORA and ACA (r = 0.17, P = 0.03), ORA and RA (r = − 0.27, P = 0.001). The magnitude of ocular residual astigmatism was relatively small in children’s astigmatic eyes. Both against-the-rule and oblique ORA can counteract with-the-rule ACA.

An analytical study of optimal roller intermeshes for the plate leveling process

Leveling process is usually used to minimize the plate defects including flatness imperfections and uniformity of internal stress in the plate industry. Roller intermeshes are important parameters in the leveling process to ensure the high-quality leveled plate. Some current researches treat the plate as a simple beam and ignore the stress superimposed effect to study how to set the roller intermeshes. This article presents an analytical optimization model to search the optimal entry and exit intermeshes for each incoming plate with consideration of the relationship between the roller intermeshes and bending curvatures during the whole leveling process. The optimization model was solved and the results were verified with production data. The relationship between the optimal roller intermeshes and plate thickness, yield stress, and Young’s modulus were discussed in details. It was found out that the roller intermeshes can be set the same for different incoming plates but with equal elastic limit curvature. A four-dimensional database of optimal roller intermeshes about different elastic limit curvature, expected plastic strain ratios, and roller spaces was built. The roller intermeshes can be quickly tracked in less than 1 s as long as the thickness, yield stress, and Young’s modulus of incoming plate and roller space are given according to the database so that it can be used effectively on the leveling production line.

Research Progress of Buton Rock Asphalt in Road Pavement Materials

A large number of domestic and international literatures have studied the pavement performance of composite modification of Buton rock asphalt and different asphalt modifiers. It is found that basalt blending can greatly improve the performance in an all-round way, in which high-temperature stability and low-temperature cracking resistance have superimposed effect. Waste rubber powder blending has little overall performance improvement. With diatomite blending the performance can exceed SBS modified asphalt. The research on composite modification of Buton rock asphalt still needs further study.

Analysis of the influence of train load characteristics on the water damage of slab tracks

High-speed train load is one of the main factors that causes the failure of a slab track and is also the direct cause for producing water pressure in the cracks. Hence, choosing the right loading method is the key to analyze the water damage of slab tracks. In order to identify the distribution characteristics of the vertical force acting on the slab track, the analytic expression of fastener load was derived, and the field test was conducted to verify the theoretical model. According to the distribution characteristics of fastener load and the area of crack filled with water, the loading method was presented to analyze the water damage of slab tracks, and the influence of loading characteristics on the hydrodynamic pressure and crack propagation was analyzed. The results show that the distribution of fastener load in the main affected zone approximately accords with the Gaussian distribution under the single wheel load. When under the action of double wheels, the superimposed effect makes the second derivative of the loading function to increase by 99.93%. The superimposed effect of three or more wheels is less than 1% and can be ignored. Considering that the hydrodynamic pressure is highly sensitive to the second derivative of loading function, the load applied on the track slab should be in the form of a bogie, and different loads should be applied step by step based on the time series. The distribution of hydrodynamic pressure along the crack is approximately equal to the cubic polynomial, and the pressure peak appears at the crack tip. Also, the pressure is proportional to the square of the running speed of the train. In the region with abundant rainwater and a poor drainage system, reducing the train speed and taking timely measures such as grouting can effectively reduce the water damage of slab tracks.

The Superimposed Deubiquitination Effect of OTULIN and Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Nsp11 Promotes Multiplication of PRRSV

ABSTRACTLinear ubiquitination plays an important role in the regulation of the immune response by regulating nuclear factor κB (NF-κB). The linear ubiquitination-specific deubiquitinase ovarian tumor domain deubiquitinase with linear linkage specificity (OTULIN) can control the immune signaling transduction pathway by restricting the Met1-linked ubiquitination process. In our study, the porcine OTLLIN gene was cloned and deubiquitin functions were detected in a porcine reproductive and respiratory syndrome virus (PRRSV)-infected-cell model. PRRSV infection promotes the expression of the OTULIN gene; in turn, overexpression of OTULIN contributes to PRRSV proliferation. There is negative regulation of innate immunity with OTULIN during viral infection. The cooperative effects of swine OTULIN and PRRSV Nsp11 potentiate the ability to reduce levels of cellular protein ubiquitin associated with innate immunity. Importantly, PRRSV Nsp11 recruits OTULIN through a nonenzymatic combination to enhance its ability to remove linear ubiquitination targeting NEMO, resulting in a superimposed effect that inhibits the production of type I interferons (IFNs). Our report presents a new model of virus utilization of the ubiquitin-protease systemin vivofrom the perspective of the viral proteins that interact with cell deubiquitination enzymes, providing new ideas for prevention and control of PRRSV.IMPORTANCEDeubiquitination effects of swine OTULIN were identified. The interaction between porcine OTULIN and PRRSV Nsp11 is dependent on the OTU domain. PRRSV Nsp11 recruits OTULIN through a nonenzymatic combination to promote removal of linear ubiquitination targeting NEMO, resulting in a superimposed effect that inhibits the production of type I IFNs.