scholarly journals Corneal ectasia in mothers of Down syndrome children

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hassan Hashemi ◽  
Soheila Asgari ◽  
Parsa Panahi ◽  
Shiva Mehravaran ◽  
Akbar Fotouhi ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Random Forest ◽  
Clinical Sign ◽  
Prevalence Rates ◽  
Normal Subgroups ◽  
Amplitude Ratios ◽  
Normal Children ◽  
Irregularity Index ◽  
Deflection Amplitude ◽  
Biomechanical Parameters

AbstractIn this study, corneal findings regarding keratoconus (KC) and early KC among mothers with Down syndrome children (MDS) and a group of age-at-delivery-matched mothers with normal children (MNC) were compared. KC was diagnosed based on the presence of a clinical sign and at least one abnormal tomographic or biomechanical criterion. Early KC was defined as having no clinical sign in the presence of at least one abnormal tomographic or biomechanical criterion. The normal subgroups in each group were compared in terms tomographic and biomechanical parameters. In MDS and MNC, the prevalence rates were 6.5% and 1.6% for KC (P = 0.047), and 30.9% and 14.3% for early KC (P = 0.014), respectively. Comparison between the two normal subgroups showed significant differences in mean index of height asymmetry, irregularity index, anterior asphericity, pentacam random forest index, corneal stiffness parameters at first applanation, deformation amplitude ratios, integrated radius-1 mm, highest concavity deflection amplitude, biomechanical corrected IOP, peak distance, and radius (all P < 0.05). This study showed that MDS are more likely to have KC and also to have thinner, steeper and softer corneas compared to MNC. This results support the need for further work for determining the risk of delivering a child with DS.

scholarly journals Corneal Ectasia in Mothers of Down Syndrome Children

2021 ◽  
Author(s):  
Hassan Hashemi ◽  
Soheila Asgari ◽  
Parsa Panahi ◽  
Shiva Mehravaran ◽  
Akbar Fotouhi ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Random Forest ◽  
Clinical Sign ◽  
Prevalence Rates ◽  
Normal Subgroups ◽  
Amplitude Ratios ◽  
Normal Children ◽  
Irregularity Index ◽  
Deflection Amplitude ◽  
Biomechanical Parameters

Abstract In this study, corneal findings regarding keratoconus (KC) and early KC among mothers with Down syndrome children (MDS) and a group of age-at-delivery-matched mothers with normal children (MNC) were compared. KC was diagnosed based on the presence of a clinical sign and at least one abnormal tomographic or biomechanical criterion. Early KC was defined as having no clinical sign in the presence of at least one abnormal tomographic or biomechanical criterion. The normal subgroups in each group were compared in terms tomographic and biomechanical parameters. In MDS and MNC, the prevalence rates were 6.5% and 1.6% for KC (P = 0.047), and 30.9% and 14.3% for early KC (P = 0.014), respectively. Comparison between the two normal subgroups showed significant differences in mean index of height asymmetry, irregularity index, anterior asphericity, pentacam random forest index, corneal stiffness parameters at first applanation, deformation amplitude ratios, integrated radius-1mm, highest concavity deflection amplitude, biomechanical corrected IOP, peak distance, and radius (all P < 0.05). This study showed that MDS are more likely to have KC and also to have thinner, steeper and softer corneas compared to MNC. This results support the need for further work for determining the risk of delivering a child with DS.

scholarly journals Physical Growth and Echocardiographic Findings in Children with Down Syndrome

2017 ◽  
Vol 38 (3-4) ◽  
pp. 54
Author(s):  
Sudigdo Sastroasmoro ◽  
Mathilda Y. Lnkiriwang ◽  
Bambang Madiyono ◽  
Lsmet N Oesman
Keyword(s):  
Down Syndrome ◽  
Nutritional Status ◽  
Posterior Wall ◽  
Left Ventricular ◽  
Physical Growth ◽  
Normal Children ◽  
Children With Down Syndrome ◽  
Significant Difference ◽  
Nutritional Status Of Children ◽  
Echocardiographic Findings

We compared the physical growth, nutritional status, and echocardiographic findings in children aged 3-7 years with Down syndrome who had no congenital heart disease. Thirty such patients who consecutively referred to the Division of Cardiology, Department of Child Health, Medical School, University of Indonesia/Cipto Mangunkusumo Hospital, Jakarta, were compared with sex and age matched controls consisted of normal children attending the Department. It appears that growth and nutritional status of children with Down syndrome tended to be retarded when compared to those of the controls. However, no significant difference were found on the M-mode echocardiographic values of the left ventricle, except that the left ventricular posterior wall thickness in study subjects was more that that of the controls. We concluded that although the pulmonary architecture of patients with Down syndrome is thought to be less developed than that of normal children, it does not affect the left ventricular measurements and function as measured by M-mode echocardiography.

Changes in yearly birth prevalence rates of children with Down syndrome in the period 1986-2007 in the Netherlands

2011 ◽  
Vol 55 (5) ◽  
pp. 462-473 ◽  
Author(s):  
G. de Graaf ◽  
M. Haveman ◽  
R. Hochstenbach ◽  
J. Engelen ◽  
K. Gerssen-Schoorl ◽  
...  
Keyword(s):  
Down Syndrome ◽  
The Netherlands ◽  
Prevalence Rates ◽  
Birth Prevalence ◽  
Children With Down Syndrome

Marital Intimacy in Parents of Exceptional Children

1989 ◽  
Vol 34 (6) ◽  
pp. 519-525 ◽  
Author(s):  
Sandra N. Fisman ◽  
Lucille C. Wolf ◽  
Samuel Noh
Keyword(s):  
Down Syndrome ◽  
Parenting Stress ◽  
Self Esteem ◽  
Autistic Children ◽  
Exceptional Children ◽  
Normal Children ◽  
Handicapped Children ◽  
Perceived Parenting ◽  
Marital Intimacy

The purpose of this study was to examine the role of perceived parenting stress and parental depression on marital intimacy between parents of handicapped children versus developmentally normal children, and to investigate discrepancies between husbands' and wives' reports of marital intimacy. The parents of 31 autistic children, 31 Down Syndrome children and 62 developmentally normal children, matched for both mental and chronological age were studied. Results indicated significantly greater stress and depression, as well as lower marital intimacy for mothers of autistic children than mothers of normal children, and significantly greater stress than mothers of Down Syndrome children who fell somewhere between other groups of parents in all three measures. Fathers of autistic children experienced significantly higher parenting stress than the other groups, as well as lower marital intimacy but there were no differences amongst fathers on measures of depression. Low scores on subscales of identity and compatibility for mothers implying low self esteem contributed significantly to the lowered perception of marital intimacy. Implications for intervention, based on these findings, are discussed.

Communicative Profiles of Preschool Children with Handicaps

1989 ◽  
Vol 54 (2) ◽  
pp. 148-158 ◽  
Author(s):  
Amy M. Wetherby ◽  
Dianne G. Yonclas ◽  
Amy A. Bryan
Keyword(s):  
Down Syndrome ◽  
Preschool Children ◽  
Language Impairments ◽  
Normal Range ◽  
Normal Children ◽  
Intentional Communication ◽  
Specific Language ◽  
Specific Language Impairments ◽  
Standard Sampling ◽  
Sampling Procedures

The purpose of this study was to compare the communicative profiles of preschool children with handicaps to those of normal children functioning in the prelinguistic and one-word stage using standard sampling procedures. The children with handicaps included 4 with Down syndrome, 4 with specific language impairments, and 3 with autism. Measures obtained from the communication samples included rates of intentional communication and proportions of communicative functions, discourse structure, communicative means, and syllabic shape. The results of the children with Down syndrome fell within the normal range on all parameters. The common pattern displayed by the children with specific language impairments was a deviation in syllabic shape. The children with autism displayed adequate rates of communicating but fell outside of the normal range for their language stage on the other communicative parameters. Clinical implications of these findings for the early identification of children with communicative impairments are discussed.

Abnormal Oral Vascular Network Pattern Geometry: A New Clinical Sign of Down Syndrome

2006 ◽  
Vol 148 (1) ◽  
pp. 132-137 ◽  
Author(s):  
Giuseppe Latini ◽  
Giorgio Bianciardi ◽  
Stefano Parrini ◽  
Ricardo N. Laurini ◽  
Claudio De Felice
Keyword(s):  
Down Syndrome ◽  
Clinical Sign ◽  
Vascular Network ◽  
Network Pattern

scholarly journals APPLICATION OF THE FORWARD CHAINING METHOD IN DOWN SYNDROME PATIENTS

2019 ◽  
Vol 12 (2) ◽  
pp. 75
Author(s):  
Kurniati .
Keyword(s):  
Down Syndrome ◽  
Early Detection ◽  
Early Age ◽  
Normal Children ◽  
Live Births ◽  
Forward Chaining ◽  
The People ◽  
Decent Life ◽  
The World ◽  
The Right

According to WHO data, the incidence of Down syndrome is 1 in 1,000 live births in the world. Down syndrome is a backward condition in the physical and mental development of children that results from abnormal chromosome development. However, these conditions are often too late to be realized by the parents of the sufferer. By conducting this study using the forward chaining method aims to help parents to do early detection of the level of retardation of Down syndrome. So, with the existence of this application, it is very petrifying for parents to carry out treatment from an early age in the right way. Thus, sufferers of dwon syndrome get maximum support and attention from the people closest and nearby so that children with dwon syndrome can grow happily and have a decent life like other normal children even though this dwon syndrome cannot be cured. 

scholarly journals MELATIH KEMANDIRIAN ANAK DOWN SYNDROME DENGAN MOTOTRAIN

2020 ◽  
Vol 13 (2) ◽  
Author(s):  
Machmudah Machmudah ◽  
Mochammad Shodiq
Keyword(s):  
Down Syndrome ◽  
Intervention Group ◽  
Sampling Technique ◽  
Toilet Training ◽  
Control Group ◽  
P Value ◽  
Maternal Knowledge ◽  
Normal Children ◽  
Children With Down Syndrome ◽  
Mothers And Children

Practicing toilet training from parents to children is quite challenging especially if the child has special needs. For children with Down syndrome, the habit of toilet training takes longer than normal children who can be completed before school age. The purpose of this study was to determine the effectiveness of Mototrain on maternal knowledge and independence of toilet training in children with Down syndrome. Mototrain is an acronym for Module of Toilet Training. The population and sample in this study were parents and students with Down syndrome who had not yet completed their toilet training independence, namely 31 students spread across Grade 1, Grade 2, Grade 3, Grade 4 and Grade 5 in SD C Alpha Kumara. The research design was "Quasi experimental pre-post test with control group", with a purposive sampling technique of 16 mothers and children in the intervention group and 15 mothers and children in the control group. The results showed an increase in maternal knowledge about toilet training and the independence of toilet training in children who used enough after being given psychoeducation and habituation in accordance with MOTOTRAIN (p-value <0.05).

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