scholarly journals Acute surgical site infection after total knee arthroplasty in patients with rheumatoid arthritis versus osteoarthritis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ho-Ken Chung ◽  
Shu-Hui Wen ◽  
Wei-Chuan Chang ◽  
Kuan-Lin Liu

AbstractOsteoarthritis is the main cause for total knee arthroplasty (TKA), followed by rheumatoid arthritis. Previous studies have reported conflicting results concerning the risk of surgical site infection after TKA for rheumatoid arthritis and osteoarthritis patients. Thus, this study aimed to examine whether rheumatoid arthritis patients had a higher risk of acute surgical site infection after TKA compared to osteoarthritis patients. We conducted a retrospective cohort study using Taiwan’s National Health Insurance Research Database of the whole population from 2012 to 2015, and collected the medical records of osteoarthritis patients or rheumatoid arthritis patients who underwent TKA. To evaluate the risk of acute surgical site infection in rheumatoid arthritis patients, propensity score matching was implemented for osteoarthritis patients. Acute surgical site infection was observed in 2.58% of TKA cases in rheumatoid arthritis patients and 2.66% of TKA cases in osteoarthritis patients. Rheumatoid arthritis and osteoarthritis patients had comparable risk for 90-day (odds ratio = 0.81, 95% confidence interval: 0.371–1.768) and 1-year (odds ratio = 0.463, 95% confidence interval: 0.121–1.766) surgical site infection. In conclusion, patients with rheumatoid arthritis were not at higher risk of acute surgical site infection after TKA compared to osteoarthritis patients. The current treatment strategy for patients with RA is safe and appropriate if they require TKA.

2021 ◽  
Author(s):  
Ho-Ken Chung ◽  
Shu-Hui Wen ◽  
Wei-Chuan Chang ◽  
Kuan-Lin Liu

Abstract Osteoarthritis is the main cause for total knee arthroplasty, followed by rheumatoid arthritis. Previous studies have reported conflicting results concerning the risk of periprosthetic infection after total knee arthroplasty for rheumatoid arthritis and osteoarthritis patients. Thus, this study aimed to examine whether rheumatoid arthritis patients had a higher risk of acute periprosthetic infection after total knee arthroplasty compared to osteoarthritis patients. We conducted a retrospective cohort study using Taiwan’s National Health Insurance Research Database of the whole population from 2012 to 2015, and collected the medical records of osteoarthritis patients or rheumatoid arthritis patients who underwent total knee arthroplasty. To evaluate the risk of acute periprosthetic infection in rheumatoid arthritis patients, propensity score matching was implemented for osteoarthritis patients. Acute periprosthetic infection was observed in 2.58% of total knee arthroplasty cases in rheumatoid arthritis patients and 2.66% of total knee arthroplasty cases in osteoarthritis patients. Rheumatoid arthritis and osteoarthritis patients had comparable risk for 90-day and one-year periprosthetic infection. In conclusion, patients with rheumatoid arthritis were not at higher risk of acute periprosthetic infection after total knee arthroplasty compared to osteoarthritis patients. The current treatment strategy for patients with rheumatoid arthritis undergoing total knee arthroplasty is safe and appropriate.


2017 ◽  
Vol 3 (1) ◽  
pp. 57-60 ◽  
Author(s):  
Jorge Manrique ◽  
Antonia F. Chen ◽  
Miguel M. Gomez ◽  
Mitchell G. Maltenfort ◽  
William J. Hozack

2018 ◽  
Vol 15 (2) ◽  
pp. 328-332 ◽  
Author(s):  
Christopher John Wilson ◽  
Kristen Renee Georgiou ◽  
Ezekiel Oburu ◽  
Annika Theodoulou ◽  
Angela H. Deakin ◽  
...  

2015 ◽  
Vol 30 (12) ◽  
pp. 2271-2274 ◽  
Author(s):  
Geoffrey W. Siegel ◽  
Neil N. Patel ◽  
Michael A. Milshteyn ◽  
David Buzas ◽  
Daniel J. Lombardo ◽  
...  

2018 ◽  
Vol 26 (2) ◽  
pp. 230949901878564 ◽  
Author(s):  
Bryon Jun Xiong Teo ◽  
William Yeo ◽  
Hwei-Chi Chong ◽  
Andrew Hwee Chye Tan

Purpose: Surgical site infection (SSI) is a serious complication following total knee arthroplasty (TKA) leading to considerable morbidity. The incidence is reported to be up to 2%. Risk factors continue to be an area of intense debate. Our study aims to report the incidence of SSI and identify possible risk factors in our patients undergoing TKA. Methods: Prospectively collected data for 905 patients who underwent elective unilateral TKA by a single surgeon from February 2004 to July 2014 were reviewed. Patient demographics and relevant co-morbidities such as diabetes and heart disease were analysed. The presence of superficial wound infections and/or prosthetic joint infections was included. Results: The overall infection rate was 1.10% (10 of 905 patients). Six patients (0.66%) were diagnosed with superficial infections and four with PJI (0.44%). The mean operative duration for TKA with SSI was significantly longer at 90.5 ± 28.2 min, compared to 72.2 ± 20.3 min in TKA without SSI ( p = 0.03). All superficial infections occurred within the first month post-surgery and were self-limiting with oral antibiotics. The four patients with PJI required repeated procedures following TKA, including debridement, implant removal and/or revision arthroplasty. None of the 10 patients had a history of diabetes. There were no significant differences in demographics and co-morbidities between those who developed infection after TKA and those who did not. Conclusion: An overwhelming majority had good outcomes with only four deep infections resulting in revision surgery. We report that the risk of infection in TKA was significantly associated with a longer operative duration.


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