scholarly journals Retrieval of 3D information in X-ray dark-field imaging with a large field of view

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jana Andrejewski ◽  
Fabio De Marco ◽  
Konstantin Willer ◽  
Wolfgang Noichl ◽  
Theresa Urban ◽  
...  

AbstractX-ray dark-field imaging is a widely researched imaging technique, with many studies on samples of very different dimensions and at very different resolutions. However, retrieval of three-dimensional (3D) information for human thorax sized objects has not yet been demonstrated. We present a method, similar to classic tomography and tomosynthesis, to obtain 3D information in X-ray dark-field imaging. Here, the sample is moved through the divergent beam of a Talbot–Lau interferometer. Projections of features at different distances from the source seemingly move with different velocities over the detector, due to the cone beam geometry. The reconstruction of different focal planes exploits this effect. We imaged a chest phantom and were able to locate different features in the sample (e.g. the ribs, and two sample vials filled with water and air and placed in the phantom) to corresponding focal planes. Furthermore, we found that image quality and detectability of features is sufficient for image reconstruction with a dose of 68 μSv at an effective pixel size of $$0.357 \times {0.357}\,\mathrm{mm}^{2}$$ 0.357 × 0.357 mm 2 . Therefore, we successfully demonstrated that the presented method is able to retrieve 3D information in X-ray dark-field imaging.

Author(s):  
Sascha Senck ◽  
Michael Scheerer ◽  
Vincent Revol ◽  
Bernhard Plank ◽  
Christian Hannesschläger ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Andreas P. Sauter ◽  
Jana Andrejewski ◽  
Manuela Frank ◽  
Konstantin Willer ◽  
Julia Herzen ◽  
...  

AbstractGrating-based X-ray dark-field imaging is a novel imaging modality with enormous technical progress during the last years. It enables the detection of microstructure impairment as in the healthy lung a strong dark-field signal is present due to the high number of air-tissue interfaces. Using the experience from setups for animal imaging, first studies with a human cadaver could be performed recently. Subsequently, the first dark-field scanner for in-vivo chest imaging of humans was developed. In the current study, the optimal tube voltage for dark-field radiography of the thorax in this setup was examined using an anthropomorphic chest phantom. Tube voltages of 50–125 kVp were used while maintaining a constant dose-area-product. The resulting dark-field and attenuation radiographs were evaluated in a reader study as well as objectively in terms of contrast-to-noise ratio and signal strength. We found that the optimum tube voltage for dark-field imaging is 70 kVp as here the most favorable combination of image quality, signal strength, and sharpness is present. At this voltage, a high image quality was perceived in the reader study also for attenuation radiographs, which should be sufficient for routine imaging. The results of this study are fundamental for upcoming patient studies with living humans.


2011 ◽  
Vol 110 (10) ◽  
pp. 109902 ◽  
Author(s):  
Michael Chabior ◽  
Tilman Donath ◽  
Christian David ◽  
Manfred Schuster ◽  
Christian Schroer ◽  
...  

2019 ◽  
pp. 75-96
Author(s):  
Deniz A. Bölükbas ◽  
Darcy E. Wagner

1999 ◽  
Vol 38 (Part 2, No. 12A) ◽  
pp. L1485-L1487 ◽  
Author(s):  
Hidekazu Takano ◽  
Kazuhiro Yokota ◽  
Sadao Aoki

2014 ◽  
Vol 22 (19) ◽  
pp. 23276 ◽  
Author(s):  
André Ritter ◽  
Peter Bartl ◽  
Florian Bayer ◽  
Karl C. Gödel ◽  
Wilhelm Haas ◽  
...  

2011 ◽  
Vol 17 (5) ◽  
pp. 759-765 ◽  
Author(s):  
Tanmay Das ◽  
Somnath Bhattacharyya

AbstractStructure and chemistry across the rare earth oxide-Ge interfaces of a Gd2O3-Ge-Gd2O3 heterostructure grown on p-Si (111) substrate using encapsulated solid phase epitaxy method have been studied at nanoscale using various transmission electron microscopy methods. The structure across both the interfaces was investigated using reconstructed phase and amplitude at exit plane. Chemistry across the interfaces was explored using elemental mapping, high-angle annular dark-field imaging, electron energy loss spectroscopy, and energy dispersive X-ray spectrometry. Results demonstrate the structural and chemical abruptness of both the interfaces, which is most essential to maintain the desired quantum barrier structure.


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