scholarly journals Characteristics of progressive temporal visual field defects in patients with myopia

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jiyun Lee ◽  
Chan Kee Park ◽  
Kyoung In Jung

AbstractTemporal visual field damage (VFD) is the common type of non-glaucomatous VF defects found in eyes with myopia. However, little is known about the factors associated with its progression. We investigated the characteristic of myopic eyes with progressive temporal VF defects. This retrospective, observational study included a total of 116 eyes: 39 eyes with temporal VFDs and an axial length greater than 24.5 mm, 77 eyes with typical glaucomatous VFDs who were followed up more than 5 years. VF progression was evaluated with Trend-based global progression analysis. In the temporal VFD group, the greater tilt ratios, the higher prevalence of β-zone peripapillary atrophy (β-PPA), the substantial increase in β-PPA were found, compared to the typical glaucomatous VFD groups (all P-values ≤ 0.001). The temporal VFD group had the slower progression than the typical glaucomatous VFD group on trend-based GPA (P = 0.047). In the multivariate linear regression analysis, the change of β-PPA area over years was related to temporal VFD progression (B, − 0.000088, P = 0.003). In conclusion, myopic eyes with the temporal VFD, which come with growing β-PPA area, should be monitored with extra caution.

1992 ◽  
Vol 2 (4) ◽  
pp. 169-174 ◽  
Author(s):  
J. Flammer ◽  
Y. Kitazawa ◽  
L. Bonomi ◽  
B. Mills ◽  
M. Fsadni ◽  
...  

The influences of Carteolol and Timolol eye drops on intraocular pressure (IOP) and visual fields were compared in a multi-center, double-masked, prospective study. Two-hundred and forty eyes of 120 patients were initially included in the study, and 142 eyes of 72 patients fulfilled all the criteria for final statistical analysis. Both drugs significantly reduced IOP. The visual fields in both treatment groups did not change during one year of treatment. In both groups some patients improved slightly, and others deteriorated slightly. This indicates that locally applied beta-blockers may efficiently stop further progression of visual field defects in cases with increased IOP and early visual field damage. There was no difference between Carteolol and Timolol in this regard. The side effects were minimal, and there were no differences in their frequency or intensity in the two treatment groups.


Stroke ◽  
2021 ◽  
Vol 52 (Suppl_1) ◽  
Author(s):  
Sang Min Paik ◽  
Steven C Cramer

Introduction: Higher doses of rehabilitation therapy are associated with better outcomes after stroke. Many patients do not receive high-dose therapy, however, e.g., due to limited availability and access, especially in the COVID era. Telehealth approaches can overcome many barriers, and evidence suggests that some forms of telerehabilitation are efficacious after stroke. However, uncertainty exists as to which patients are most likely to benefit from telerehabilitation. This issue was examined in the current study. Methods: Data are from patients randomized to telerehabilitation (TR) in an 11-site, assessor-blind trial (JAMA Neurol 76:1079) that provided 6 weeks of intensive arm motor therapy to hemiparetic patients with stroke 4-36 weeks prior. The primary endpoint was change in arm motor Fugl-Meyer (FM) from pre-treatment to 1-month post-treatment. Predictors of TR-related FM gain were identified using forward stepwise multivariable linear regression analysis, advancing the most significant predictor from each of 8 categories (demographics, stroke characteristics, medical history, amount of outside therapy, motivation, sensorimotor impairment, cognitive/affective status, and functional status) if it survived bivariate screening with p<0.1. Results: In patients >90 days post-stroke onset (n=44), sex (r=.33, p=.028), # hours of outside therapy post-randomization (r=.36, p=.019), spasticity (r=-.37, p=.014), and NIHSS visual field score (r=-.28, p=.068) were bivariate predictors of TR-related FM gain. In multivariable analysis, all except therapy hours survived as significant (P<0.05) predictors: TR-related FM gains were higher in females and lower in patients with spasticity or visual field defects. When the 15 patients randomized to TR ≤90 days post-stroke were added in secondary analysis, multivariable analysis found that sex, # hours of therapy post-randomization, and NIHSS neglect score were significant predictors. Conclusions: In patients with stable motor status >90 days post-stroke, behavioral gains from home-based TR were greatest in patients who were female and who had less spasticity and visual field defects. These results might be useful for patient selection and for design of future TR-based therapeutic approaches.


PLoS ONE ◽  
2018 ◽  
Vol 13 (4) ◽  
pp. e0196001 ◽  
Author(s):  
Kyoung Min Lee ◽  
Se Joon Woo ◽  
Jeong-Min Hwang

2021 ◽  
Vol 223 ◽  
pp. 229-240
Author(s):  
Eren Ekici ◽  
Sasan Moghimi ◽  
Huiyuan Hou ◽  
James Proudfoot ◽  
Linda M. Zangwill ◽  
...  

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