Exercise capacity of untrained spinal cord injured individuals and the relationship of peak oxygen uptake to level of injury

Introduction: End-stage renal disease (ESRD) is one of the most common diseases, which affects many aspects of patients’ lives. The measurement of exercise capacity through peak oxygen uptake is an important factor in predicting mortality and survival in patients with ESRD. Objectives: In the current study, we aimed to examine the relationship between phosphorus level and VO2 uptake in renal transplant candidates receiving hemodialysis. Patients and Methods: Thirty renal transplant candidates on hemodialysis were evaluated through spirometry and exercise tests. Then, the results were compared according to the inclusion criteria of age, gender, and phosphorus level. Results: All of cases were male with the mean age of 37.93±10.48 years (range; 20-55 years). Mean VO2 max was 23.46±8.22 mL/kg/min (range; 6.88 to 43.44 mL/kg/min). The mean phosphorus level was 6±2.3 mg/dL (range; 2-10.6 mg/dL) since eight patients had high levels of phosphorus (more than 5.5 mg/dL). In patients with low phosphorus level an abnormal VO2 max was detected (P=0.027). Furthermore, Fisher’s exact test reflected a significant association between higher levels of phosphorus with normal VO2 max (P=0.029). Conclusion: In hemodialysis, decreased blood phosphorus is a predisposing factor for reduced exercise capacity, while hypophosphatemia may lower VO2 max through reducing energy of skeletal muscles. The relationship between phosphorus level and VO2 max may be related to morbidity in hemodialysis patients. Hence, treatment modalities reducing serum levels of phosphorus should be conducted with caution in some patients.

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Life Outlook, Hopes, and Fears of Persons with Spinal Cord Injury

Journal of Applied Rehabilitation Counseling ◽

10.1891/0047-2220.9.3.102 ◽

1978 ◽

Vol 9 (3) ◽

pp. 102-107

Author(s):

Richard T. Roessler

Keyword(s):

Spinal Cord ◽

Independent Living ◽

Spinal Cord Injuries ◽

Population Group ◽

Rehabilitation Program ◽

The Past ◽

Cord Injury ◽

Relationship Of ◽

The Relationship ◽

Spinal Cord Injured

Seventy-five persons with spinal cord injuries completed Cantril’s Life Ladder upon admission to a comprehensive rehabilitation program. Paraplegics and quadriplegics held an optimistic view of the future and tended to view the past more favorably than did the compartive U. S. population group. Quadriplegics rated the present significantly lower than either individuals with paralegia or the normative sample. Paralleling other research with the spinal cord injured, hopes and fears for the two groups focused on health, economic, and family concerns. The percentage of SCI clients mentioning specific aspirations for congenial or steady work was small but higher than in the comparison group. In another phase of the study, comparisons of low, moderate, and high hope subgroups tended to support the relationship of moderate hope to positive rehabilitation indices. The data were discussed in terms of such concepts as idealization of the past, prepotent needs, reinforcement, realism, and independent living training.

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Cough in spinal cord injured patients: the relationship between motor level and peak expiratory flow

Spinal Cord ◽

10.1038/sj.sc.3100370 ◽

1997 ◽

Vol 35 (5) ◽

pp. 299-302 ◽

Cited By ~ 28

Author(s):

Amy Y Wang ◽

Robert J Jaeger ◽

Gary M Yarkony ◽

Rose M Turba

Keyword(s):

Spinal Cord ◽

Peak Expiratory Flow ◽

Expiratory Flow ◽

Injured Patients ◽

The Relationship ◽

Spinal Cord Injured

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The relationship of body weight on maximum oxygen uptake and heavy-work endurance capacity on the bicycle ergometer

Medicine & Science in Sports & Exercise ◽

10.1249/00005768-197100330-00001 ◽

1971 ◽

Vol 3 (3) ◽

pp. 101???106

Author(s):

FRANK I. KATCH ◽

ROBERT N. GIRANDOLA ◽

VICTOR L. KATCH

Keyword(s):

Body Weight ◽

Oxygen Uptake ◽

Bicycle Ergometer ◽

Maximum Oxygen Uptake ◽

Endurance Capacity ◽

Heavy Work ◽

Relationship Of ◽

The Relationship

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Does allogeneic stem cell transplantation in survivors of pediatric leukemia impact regular physical activity, pulmonary function, and exercise capacity?

Molecular and Cellular Pediatrics ◽

10.1186/s40348-021-00127-7 ◽

2021 ◽

Vol 8 (1) ◽

Author(s):

Katharina Ruf ◽

Alaa Badran ◽

Céline Siauw ◽

Imme Haubitz ◽

Paul-Gerhardt Schlegel ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Stem Cell ◽

Oxygen Uptake ◽

Stem Cell Transplantation ◽

Pulmonary Function ◽

Cell Transplantation ◽

Exercise Capacity ◽

Peak Oxygen Uptake

Abstract Background Allogeneic hematopoietic stem cell transplantation (allo-HSCT) has improved survival in high-risk childhood leukemia but is associated with long-term sequelae such as impaired pulmonary function and reduced exercise capacity impacting quality of life. Methods A convenience sample of 17 patients after allo-HSCT (HSCT—12 male, age 15.7±6.7 years, time after HSCT 5.3±2.8 years) underwent pulmonary function testing, echocardiography, and an incremental exercise test on a bike. Physical activity and health-related quality of life were assessed by questionnaires (7-day physical activity recall, PEDS-QL). Seventeen healthy age- and gender-matched controls served as control group (CG) for results of pulmonary function and exercise testing. Results HSCT showed reduced pulmonary function (HSCT vs. CG: FEV1 90.5±14.0 vs. 108.0±8.7%pred; FVC 88.4±19.3 vs. 107.6±6.9%pred, DLCO 75.3±23.6 vs. 104.9±12.8%pred) and exercise capacity (VO2peak 89±30.8%pred, CG 98±17.5%pred; Wmax 84±21.7%pred, CG 115±22.8%pred), but no relevant cardiac dysfunction and a good quality of life (PEDS-QL mean overall score 83.3±10.7). Differences in peak oxygen uptake between groups were mostly explained by 5 adolescent patients who underwent total body irradiation for conditioning. They showed significantly reduced diffusion capacity and reduced peak oxygen uptake. Patients reported a mean time of inactivity of 777±159min/day, moderate activity of 110±107 min/day, hard activity of 35±36 min/day, and very hard activity of 23±22 min/day. A higher amount of inactivity was associated with a lower peak oxygen uptake (correlation coefficient tau −0.48, p=0.023). Conclusions This pilot study shows that although patients after allo-HSCT reported a good quality of life, regular physical activity and exercise capacity are reduced in survivors of stem cell transplantation, especially in adolescents who are treated with total body irradiation for conditioning. Factors hindering regular physical activity need to be identified and exercise counseling should be part of follow-up visits in these patients.

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