scholarly journals Breast cancer risk factors and a novel measure of volumetric breast density: cross-sectional study

2007 ◽  
Vol 98 (1) ◽  
pp. 210-216 ◽  
Author(s):  
M Jeffreys ◽  
R Warren ◽  
R Highnam ◽  
G Davey Smith
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Breast Density ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cancer Risk Factors ◽  
Breast Cancer Risk Factors

Breast cancer risk factors and mammographic breast density in women over age 70

2005 ◽  
Vol 97 (2) ◽  
pp. 157-166 ◽  
Author(s):  
Francesmary Modugno ◽  
Duyen L. Ngo ◽  
Glenn O. Allen ◽  
Lewis H. Kuller ◽  
Roberta B. Ness ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Breast Density ◽  
Mammographic Breast Density ◽  
Cancer Risk Factors ◽  
Breast Cancer Risk Factors

scholarly journals Life course breast cancer risk factors and adult breast density (United Kingdom)

2004 ◽  
Vol 15 (9) ◽  
pp. 947-955 ◽  
Author(s):  
Mona Jeffreys ◽  
Ruth Warren ◽  
David Gunnell ◽  
Peter McCarron ◽  
George Davey Smith
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
United Kingdom ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Life Course ◽  
Breast Density ◽  
Cancer Risk Factors ◽  
Breast Cancer Risk Factors

scholarly journals Breast cancer risk factors in relation to breast density (United States)

2006 ◽  
Vol 17 (10) ◽  
pp. 1281-1290 ◽  
Author(s):  
Linda Titus-Ernstoff ◽  
Anna N. A. Tosteson ◽  
Claudia Kasales ◽  
Julia Weiss ◽  
Martha Goodrich ◽  
...  
Keyword(s):  
Breast Cancer ◽  
United States ◽  
Risk Factors ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Breast Density ◽  
Cancer Risk Factors ◽  
Breast Cancer Risk Factors

MRI background parenchymal enhancement, breast density and breast cancer risk factors: A cross-sectional study in pre- and post-menopausal women.

2020 ◽  
Author(s):  
Jennifer D Brooks ◽  
Rebecca A G Christensen ◽  
Janice S Sung ◽  
Malcolm C Pike ◽  
Irene Orlow ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Cross Sectional ◽  
Cancer Risk Factors ◽  
Background Parenchymal Enhancement ◽  
Unit Increase ◽  
Breast Cancer Risk Factors ◽  
Post Menopausal

Abstract Background: Histologically normal breast fibroglandular tissue (FGT) enhances on contrast MRI and is called background parenchymal enhancement (BPE). Having high BPE is associated with an increased risk of breast cancer. We examined the relationship between MRI-FGT (a volumetric assessment of breast density) and BPE and breast cancer risk factors.Methods: This was a cross-sectional study of 419 women without breast cancer undergoing contrast-enhanced breast MRI. All women completed a questionnaire at the time of MRI. Prevalence ratios (PR) and 95% confidence intervals (CI) describing the relationship between breast cancer risk factors and BPE and MRI-FGT were generated using modified Poisson regression. Results: In multivariable adjusted models a positive association between BMI and BPE was observed, with a 5-unit increase in BMI associated with a 16% and 38% increase in prevalence of high BPE in pre- and post-menopausal women respectively. Conversely, a strong inverse relationship between BMI and MRI-FGT was observed in both pre- (PR=0.65, 95% CI 0.57, 0.76 per 5-unit increase of BMI) and post-menopausal (PR=0.67, 95% CI 0.57, 0.79, per 5-unit increase in BMI) women. Current use of oral contraceptives was associated with high BPE while use of preventive medication (e.g., tamoxifen) was associated with low BPE. Conclusion: This study identifies patient characteristics and exposures associated with BPE and MRI-FGT. BPE is a new imaging marker of breast cancer risk. The results of this study provide further support for the role of hormonal exposures on BPE.

Breast density and breast cancer risk factors in a high-risk population

The Breast ◽  
2003 ◽  
Vol 12 (1) ◽  
pp. 10-16 ◽  
Author(s):  
J Warwick ◽  
E Pinney ◽  
R.M.L Warren ◽  
S.W Duffy ◽  
A Howell ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
High Risk ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Breast Density ◽  
High Risk Population ◽  
Risk Population ◽  
Cancer Risk Factors ◽  
Breast Cancer Risk Factors
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