scholarly journals Preliminary evidence for a role of the adrenergic nervous system in generalized anxiety disorder

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Xiaobin Zhang ◽  
Joanna Norton ◽  
Isabelle Carrière ◽  
Karen Ritchie ◽  
Isabelle Chaudieu ◽  
...  
Keyword(s):  
Nervous System ◽  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Preliminary Evidence ◽  
Generalized Anxiety ◽  
Adrenergic Nervous System

scholarly journals Sex-dependent role of CD300f immune receptor in generalized anxiety disorder

2021 ◽  
Vol 11 ◽  
pp. 100191
Author(s):  
Fernanda N. Kaufmann ◽  
Natalia Lago ◽  
Daniela Alí-Ruiz ◽  
Karen Jansen ◽  
Luciano D.M. Souza ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Generalized Anxiety ◽  
Immune Receptor

Role of Atypical Antipsychotics in the Treatment of Generalized Anxiety Disorder

CNS Drugs ◽  
2014 ◽  
Vol 28 (6) ◽  
pp. 519-533 ◽  
Author(s):  
Rachel Hershenberg ◽  
Daniel F. Gros ◽  
Olga Brawman-Mintzer
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Atypical Antipsychotics ◽  
Generalized Anxiety

scholarly journals Alcohol use in late adolescence and early adulthood: The role of generalized anxiety disorder and drinking to cope motives

2019 ◽  
Vol 204 ◽  
pp. 107480 ◽  
Author(s):  
Maddy L. Dyer ◽  
Jon Heron ◽  
Matthew Hickman ◽  
Marcus R. Munafò
Keyword(s):  
Anxiety Disorder ◽  
Alcohol Use ◽  
Generalized Anxiety Disorder ◽  
Early Adulthood ◽  
Late Adolescence ◽  
Generalized Anxiety ◽  
Drinking To Cope

scholarly journals Investigating the Role of Interpretation Bias in Mindfulness-Based Treatment of Adults With Generalized Anxiety Disorder

2020 ◽  
Vol 11 ◽  
Author(s):  
Elizabeth A. Hoge ◽  
Hannah E. Reese ◽  
Isabelle A. Oliva ◽  
Caroline D. Gabriel ◽  
Brittany M. Guidos ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Interpretation Bias ◽  
Generalized Anxiety

scholarly journals Generalized Anxiety Disorder in Adults: Focus on Pregabalin

2011 ◽  
Vol 3 ◽  
pp. CMPsy.S5069 ◽  
Author(s):  
Mark J. Boschen
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Preliminary Evidence ◽  
Future Research ◽  
Generalized Anxiety ◽  
Inhibitory Neurotransmitter ◽  
Ion Flow ◽  
Voltage Dependent ◽  
Voltage Dependent Calcium Channels ◽  
Flow Through

Generalized anxiety disorder (GAD) is a chronic illness which impacts significantly on an individual's functioning and quality of life. Pregabalin is a novel structural analogue of the inhibitory neurotransmitter GABA, acting to reduce calcium ion flow through the α2δ subunit of pre-synaptic voltage-dependent calcium channels. Pregabalin has been used in treatment of GAD in a total of eight published controlled trials. In each trial, pregabalin has demonstrated a superiority over placebo, with response rates of over 40% in all studies, including patients on lower doses. One study has provided preliminary evidence for the efficacy of pregabalin in treatment of GAD in older adults. Pregabalin is generally well tolerated, with the most common adverse events being dizziness and somnolence. Adverse effects are generally mild-to-moderate, and transient. Pregabalin has low abuse potential. Limitations of the current literature are discussed, and directions for future research are proposed.

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