scholarly journals Autophagy down regulates pro-inflammatory mediators in BV2 microglial cells and rescues both LPS and alpha-synuclein induced neuronal cell death

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Claudio Bussi ◽  
Javier Maria Peralta Ramos ◽  
Daniela S. Arroyo ◽  
Emilia A. Gaviglio ◽  
Jose Ignacio Gallea ◽  
...  
Keyword(s):  
Cell Death ◽  
Inflammatory Mediators ◽  
Neuronal Cell Death ◽  
Neuronal Cell ◽  
Alpha Synuclein ◽  
Microglial Cells ◽  
Bv2 Microglial Cells

scholarly journals Neuronal Cell Death Mechanisms in Major Neurodegenerative Diseases

2018 ◽  
Vol 19 (10) ◽  
pp. 3082 ◽  
Author(s):  
Hao Chi ◽  
Hui-Yun Chang ◽  
Tzu-Kang Sang
Keyword(s):  
Cell Death ◽  
Neurodegenerative Diseases ◽  
Neuronal Cell Death ◽  
Neuronal Cell ◽  
Alpha Synuclein ◽  
Adult Brain ◽  
Pathological Feature ◽  
The Central Nervous System ◽  
Cell Death Mechanisms ◽  
The Brain

Neuronal cell death in the central nervous system has always been a challenging process to decipher. In normal physiological conditions, neuronal cell death is restricted in the adult brain, even in aged individuals. However, in the pathological conditions of various neurodegenerative diseases, cell death and shrinkage in a specific region of the brain represent a fundamental pathological feature across different neurodegenerative diseases. In this review, we will briefly go through the general pathways of cell death and describe evidence for cell death in the context of individual common neurodegenerative diseases, discussing our current understanding of cell death by connecting with renowned pathogenic proteins, including Tau, amyloid-beta, alpha-synuclein, huntingtin and TDP-43.

Acrolein-mediated neuronal cell death and alpha-synuclein aggregation: Implications for Parkinson's disease

2018 ◽  
Vol 88 ◽  
pp. 70-82 ◽  
Author(s):  
Abeje Ambaw ◽  
Lingxing Zheng ◽  
Mitali A. Tambe ◽  
Katherine E. Strathearn ◽  
Glen Acosta ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cell Death ◽  
Neuronal Cell Death ◽  
Neuronal Cell ◽  
Alpha Synuclein ◽  
Alpha Synuclein Aggregation

Activation of microglial cells via protease-activated receptor 2 mediates neuronal cell death in cultured rat primary neuron

Nitric Oxide ◽  
2010 ◽  
Vol 22 (1) ◽  
pp. 18-29 ◽  
Author(s):  
Gyu Hwan Park ◽  
Se Jin Jeon ◽  
Hyun Myung Ko ◽  
Jae Ryun Ryu ◽  
Jong Min Lee ◽  
...  
Keyword(s):  
Cell Death ◽  
Neuronal Cell Death ◽  
Neuronal Cell ◽  
Microglial Cells ◽  
Primary Neuron ◽  
Protease Activated Receptor 2

scholarly journals Neuron Cell Death

2018 ◽  
Author(s):  
Hao Chi ◽  
Hui-Yun Chang ◽  
Tzu-Kang Sang
Keyword(s):  
Cell Death ◽  
Neurodegenerative Diseases ◽  
Physiological Condition ◽  
Neuronal Cell Death ◽  
Neuronal Cell ◽  
Alpha Synuclein ◽  
Adult Brain ◽  
Pathological Feature ◽  
Pathological Conditions ◽  
The Central Nervous System

Neuronal cell death in the central nervous system has always been a challenging process to decipher. In physiological condition, neuronal cell death is restricted in the adult brain even as people ages. However, in pathological conditions of various neurodegenerative diseases, the cell death and shrinkage of a specific brain region represent a fundamental pathological feature across different neurodegenerative diseases. In this review, we will briefly go through the general pathways of cell death and describe the evidence of the cell deaths in the context of common neurodegenerative diseases individually, discussing our current understandings of cell death in connecting with the renowned pathogenic proteins, including tau, amyloid-beta, alpha-synuclein, huntingtin, and TDP-43.

Sign in / Sign up

Export Citation Format

Share Document