Colloidal aggregation: Mechanisms and implications

2007 ◽  
pp. 68-83 ◽  
Keyword(s):  
Colloidal Aggregation

Computer Simulation of Colloidal Aggregation Induced by Directionalism of Long Range van der Waals Forces

2007 ◽  
Vol 23 (08) ◽  
pp. 1241-1246 ◽  
Author(s):  
XIONG Hai-Ling ◽  
◽  
◽  
YUAN Yong-Zhi ◽  
LI Hang ◽  
...  
Keyword(s):  
Computer Simulation ◽  
Long Range ◽  
Van Der Waals ◽  
Van Der Waals Forces ◽  
Colloidal Aggregation

scholarly journals Kinetics and proposed mechanism of the reaction of an immunoinhibition, particle-enhanced immunoassay

1997 ◽  
Vol 43 (12) ◽  
pp. 2384-2389 ◽  
Author(s):  
John C Thompson ◽  
Alan R Craig ◽  
Carol L Davey ◽  
David J Newman ◽  
Michele L Lonsdale ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Maximum Rate ◽  
Colloidal Stability ◽  
Kinetic Studies ◽  
Latex Agglutination ◽  
Equivalence Point ◽  
Colloidal Aggregation ◽  
Free Sample ◽  
Identical Fashion ◽  
Mechanism Of The Reaction

Abstract We report kinetic studies on the reaction of a latex agglutination immunoassay used to quantify phenytoin in serum. In this assay, polystyrene particles with a covalently attached analog of phenytoin react with an antiphenytoin monoclonal antibody to form light-scattering aggregates, with the rate of this reaction being decreased by addition of phenytoin from sample. In the absence of free (sample) phenytoin, this reaction did not exhibit a maximum rate of agglutination in the presence of excess antibody, i.e., an equivalence point. Furthermore, agglutination was inhibitable by free phenytoin even when the latter was added after agglutination of particles with antibody had begun. Most significantly, the immunoagglutination proceeded in an identical fashion with monovalent F(ab) fragment. These data are consistent with low-affinity immunospecific particle–antibody complexation, which then induces colloidal aggregation, without requiring immunospecific bridging by antibody molecules. The described mechanism is not generalizable to all latex agglutination immunoassays, although disturbance of colloidal stability may be a component in most assays.

Role of Sedimentation and Buoyancy on the Kinetics of Diffusion Limited Colloidal Aggregation

Langmuir ◽  
2003 ◽  
Vol 19 (26) ◽  
pp. 10710-10718 ◽  
Author(s):  
Hua Wu ◽  
Marco Lattuada ◽  
Peter Sandkühler ◽  
Jan Sefcik ◽  
Massimo Morbidelli
Keyword(s):  
Colloidal Aggregation ◽  
Diffusion Limited ◽  
Kinetics Of

scholarly journals Statistical mechanics of DNA-mediated colloidal aggregation

2006 ◽  
Vol 74 (4) ◽  
Author(s):  
Nicholas A. Licata ◽  
Alexei V. Tkachenko
Keyword(s):  
Statistical Mechanics ◽  
Colloidal Aggregation
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