Surface enhanced Raman spectroscopy as a molecular specific detection system in aqueous flow-through systems

The Analyst ◽  
1998 ◽  
Vol 123 (5) ◽  
pp. 1057-1060 ◽  
Author(s):  
N. Weißenbacher ◽  
J. Frank ◽  
H. D. Wanzenböck
Keyword(s):  
Raman Spectroscopy ◽  
Detection System ◽  
Surface Enhanced Raman Spectroscopy ◽  
Specific Detection ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Aqueous Flow ◽  
Flow Through

scholarly journals Highly sensitive and specific detection of E. coli by a SERS nanobiosensor chip utilizing metallic nanosculptured thin films

The Analyst ◽  
2015 ◽  
Vol 140 (9) ◽  
pp. 3201-3209 ◽  
Author(s):  
Sachin K. Srivastava ◽  
Hilla Ben Hamo ◽  
Ariel Kushmaro ◽  
Robert S. Marks ◽  
Christoph Grüner ◽  
...  
Keyword(s):  
Thin Films ◽  
Escherichia Coli ◽  
Raman Spectroscopy ◽  
Concentration Level ◽  
Surface Enhanced Raman Spectroscopy ◽  
Specific Detection ◽  
E Coli ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

A nanobiosensor chip, utilizing surface enhanced Raman spectroscopy on nanosculptured thin films of silver, was shown to detectEscherichia colibacteria down to the concentration level of a single bacterium.

scholarly journals Sensitive and specific detection of explosives in solution and vapour by surface-enhanced Raman spectroscopy on silver nanocubes

Nanoscale ◽  
2017 ◽  
Vol 9 (42) ◽  
pp. 16459-16466 ◽  
Author(s):  
Sultan Ben-Jaber ◽  
William J. Peveler ◽  
Raul Quesada-Cabrera ◽  
Christian W. O. Sol ◽  
Ioannis Papakonstantinou ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Specific Detection ◽  
Silver Nanocubes ◽  
Surface Enhanced ◽  
Spectral Fidelity ◽  
Surface Enhanced Raman ◽  
Order Of Magnitude ◽  
Detection Of Explosives

Silver nanocubes give an order of magnitude enhancement for the SERS based detection of explosives, whilst maintaining high spectral fidelity.

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

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