An isotopic effect in self-assembly of amphiphilic block copolymers: the role of hydrogen bonds

Soft Matter ◽  
2009 ◽  
Vol 5 (24) ◽  
pp. 5003 ◽  
Author(s):  
Rina Shvartzman-Cohen ◽  
Chun-lai Ren ◽  
Igal Szleifer ◽  
Rachel Yerushalmi-Rozen
Keyword(s):  
Block Copolymers ◽  
Hydrogen Bonds ◽  
Self Assembly ◽  
Isotopic Effect ◽  
Amphiphilic Block Copolymers

scholarly journals Polymerisation-induced self-assembly (PISA) as a straightforward formulation strategy for stimuli-responsive drug delivery systems and biomaterials: recent advances

2021 ◽  
Vol 9 (1) ◽  
pp. 38-50
Author(s):  
Hien Phan ◽  
Vincenzo Taresco ◽  
Jacques Penelle ◽  
Benoit Couturaud
Keyword(s):  
Drug Delivery ◽  
Block Copolymers ◽  
Drug Release ◽  
Self Assembly ◽  
Drug Delivery Systems ◽  
Amphiphilic Block Copolymers ◽  
Stimuli Responsive ◽  
Site Specific ◽  
On Demand ◽  
Redox Agents

Stimuli-responsive amphiphilic block copolymers obtained by PISA have emerged as promising nanocarriers for enhancing site-specific and on-demand drug release in response to a range of stimuli such as pH, redox agents, light or temperature.

3′:5′-Cyclic nucleotides: two sodium salts of cdTMP

2016 ◽  
Vol 72 (1) ◽  
pp. 35-47 ◽  
Author(s):  
Katarzyna Anna Ślepokura
Keyword(s):  
Hydrogen Bonds ◽  
Self Assembly ◽  
Cyclic Nucleotides ◽  
Cellular Level ◽  
Sodium Salts ◽  
Comprehensive Knowledge ◽  
Cyclic Phosphate ◽  
Nucleobase Orientation ◽  
Direct Inter

3′:5′-Cyclic nucleotides play an outstanding role in signal transduction at the cellular level but, in spite of comprehensive knowledge of the biological role of cyclic nucleotides, their structures are not established fully. Two hydrated sodium salts of thymidine 3′:5′-cyclic phosphate (cdTMP, C10H12N2O7P), namely sodium thymidine 3′:5′-cyclic phosphate heptahydrate, Na+·C10H12N2O7P−·7H2O or Na(cdTMP)·7H2O, (I), and sodium thymidine 3′:5′-cyclic phosphate 3.7-hydrate, Na+·C10H12N2O7P−·3.7H2O or Na(cdTMP)·3.7H2O, (II), have been obtained in crystalline form and structurally characterized, revealing one nucleotide in the asymmetric unit of (I) and eight different nucleotides in (II). All the cyclic nucleotide anions adopt a similar conformation with regard to nucleobase orientation, sugar conformation and 1,3,2-dioxaphosphorinane ring puckering. In (I), no direct inter-nucleotide hydrogen bonds are present, and adjacent nucleotide anions interactviawater-mediated and Na+-mediated contacts. In contrast, in (II), direct thymine–phosphate N—H...O inter-nucleotide hydrogen bonds occur and these are assisted by numerous inter-nucleotide C—H...O contacts, giving rise to the self-assembly of cdTMP−anions into three different ribbons. Two of these three ribbons run in the same direction, while the third is antiparallel.

scholarly journals Role of Penetrability into a Brush-Coated Surface in Directed Self-Assembly of Block Copolymers

2018 ◽  
Vol 11 (3) ◽  
pp. 3571-3581 ◽  
Author(s):  
Laura Evangelio ◽  
Marta Fernández-Regúlez ◽  
Jordi Fraxedas ◽  
Marcus Müller ◽  
Francesc Pérez-Murano
Keyword(s):  
Block Copolymers ◽  
Self Assembly ◽  
Coated Surface

Novel fluorescent amphiphilic block copolymers: Controllable morphologies and size by self-assembly

2007 ◽  
Vol 43 (7) ◽  
pp. 2891-2900 ◽  
Author(s):  
Xiaoju Lu ◽  
Shuling Gong ◽  
Lingzhi Meng ◽  
Cheng Li ◽  
Feng Liang ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Self Assembly ◽  
Amphiphilic Block Copolymers
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