Online model checking approach based parameter estimation to a neuronal fate decision simulation model in Caenorhabditis elegans with hybrid functional Petri net with extension

2011 ◽  
Vol 7 (5) ◽  
pp. 1576 ◽  
Author(s):  
Chen Li ◽  
Masao Nagasaki ◽  
Chuan Hock Koh ◽  
Satoru Miyano
2015 ◽  
Vol 16 (S17) ◽  
Author(s):  
Faraz Hussain ◽  
Christopher J Langmead ◽  
Qi Mi ◽  
Joyeeta Dutta-Moscato ◽  
Yoram Vodovotz ◽  
...  

2006 ◽  
Vol 11 (5) ◽  
pp. 1297-1301 ◽  
Author(s):  
Zhou Conghua ◽  
Chen Zhenyu

2001 ◽  
Vol 18 ◽  
pp. 747-754
Author(s):  
Chumchoke NANTHAWICHIT ◽  
Takashi NAKATSUJI

2020 ◽  
Author(s):  
Haojin Zhao ◽  
Roland Baatz ◽  
Carsten Montzka ◽  
Harry Vereecken ◽  
Harrie-Jan Hendricks Franssen

<p>Soil moisture plays an important role in the coupled water and energy cycles of the terrestrial system. However, the characterization of soil moisture at the large spatial scale is far from trivial. To cope with this challenge, the combination of data from different sources (in situ measurements by cosmic ray neutron sensors, remotely sensed soil moisture and simulated soil moisture by models) is pursued. This is done by multiscale data assimilation, to take the different resolutions of the data into account. A large number of studies on the assimilation of remotely sensed soil moisture in land surface models has been published, which show in general only a limited improvement in the characterization of root zone soil moisture, and no improvement in the characterization of evapotranspiration. In this study it was investigated whether an improved modelling of soil moisture content, using a simulation model where the interactions between the land surface, surface water and groundwater are better represented, can contribute to extracting more information from SMAP data. In this study over North-Rhine-Westphalia, the assimilation of remotely sensed soil moisture from SMAP in the coupled land surface-subsurface model TSMP was tested. Results were compared with the assimilation in the stand-alone land surface model CLM. It was also tested whether soil hydraulic parameter estimation in combination with state updating could give additional skill compared to assimilation in CLM stand-alone and without parameter updating. Results showed that modelled soil moisture by TSMP did not show a systematic bias compared to SMAP, whereas CLM was systematically wetter than TSMP. Therefore, no prior bias correction was needed in the data assimilation. The results illustrate how the difference in simulation model and parameter estimation result in significantly different estimated soil moisture contents and evapotranspiration.  </p>


2004 ◽  
Vol 1 (1) ◽  
pp. 27-37 ◽  
Author(s):  
Mika Matsui ◽  
Sachie Fujita ◽  
Shunichi Suzuki ◽  
Hiroshi Matsuno ◽  
Satoru Miyano

Summary Matsuno et al.[1] modeled and simulated that multicellular patterning by the Drosophila Delta-Notch signaling pathway by using the software “Genomic Object Net” which was developed based on hybrid functional Petri net (HFPN) architecture. In this model, cellular formation is fixed throughout the simulation. This paper constructs an HFPN model of the Xenopus cell cycle pathway, which includes the mechanism for cell division control as well as checkpoint processes. This model simulates dynamic cell division processes of the early Xenopus embryo, including the changes in cell division cycles from synchronous to asynchronous.


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