A water-soluble and specific BODIPY-based fluorescent probe for hypochlorite detection and cell imaging

2013 ◽  
Vol 5 (20) ◽  
pp. 5589 ◽  
Author(s):  
Guangfei Wu ◽  
Fang Zeng ◽  
Shuizhu Wu
2018 ◽  
Vol 15 (1) ◽  
pp. 47-55
Author(s):  
Xuebing Li ◽  
Haifen Yang ◽  
Ning Wang ◽  
Tijian Sun ◽  
Wei Bian ◽  
...  

Background: Morin has many pharmacological functions including antioxidant, anticancer, anti-inflammatory, and antibacterial effects. It is commonly used in the treatment of antiviral infection, gastropathy, coronary heart disease and hepatitis B in clinic. However, researches have shown that morin is likely to show prooxidative effects on the cells when the amount of treatment is at high dose, leading to the decrease of intracellular ATP levels and the increase of necrosis process. Therefore, it is necessary to determine the concentration of morin in biologic samples. Method: Novel water-soluble and green nitrogen and sulfur co-doped carbon dots (NSCDs) were prepared by a microwave heating process with citric acid and L-cysteine. The fluorescence spectra were collected at an excitation wavelength of 350 nm when solutions of NSCDs were mixed with various concentrations of morin. Results: The as-prepared NSCDs were characterized by transmission electron microscopy, X-ray diffraction and X-ray photoelectron spectroscopy. The fluorescence intensity of NSCDs decreased significantly with the increase of morin concentration. The fluorescence intensity of NSCDs displayed a linear response to morin in the concentration 0.10-30 μM with a low detection limit of 56 nM. The proposed fluorescent probe was applied to analysis of morin in human body fluids with recoveries of 98.0-102%. Conclusion: NSCDs were prepared by a microwave heating process. The present analytical method is sensitive to morin. The quenching process between NSCDs and morin is attributed to the static quenching. In addition, the cellular toxicity on HeLa cells indicated that the as-prepared NSCDs fluorescent probe does not show obvious cytotoxicity in cell imaging. Our proposed method possibly opens up a rapid and nontoxic way for preparing heteroatom doped carbon dots with a broad application prospect.


The Analyst ◽  
2019 ◽  
Vol 144 (11) ◽  
pp. 3620-3634 ◽  
Author(s):  
Rajshree Singh ◽  
Kheyanath Mitra ◽  
Shikha Singh ◽  
Sudipta Senapati ◽  
Vijay Kumar Patel ◽  
...  

ATC-PNVP showed highly efficient and selective fluorescence ‘turn off’ sensing towards picric acid and was also an effective fluorescent probe for cell imaging/tracking.


The Analyst ◽  
2021 ◽  
Author(s):  
Woohyun Lee ◽  
Tesla Yudhistira ◽  
Wongu Youn ◽  
Sol Han ◽  
Mahesh B. Halle ◽  
...  

We report a new fluorescent probe (Myco-Cys) for live cell cysteine imaging. Myco-Cys contains a methacrylate cleavable pendant group that preferentially reacts with cysteine over homocysteine and glutathione to afford a “turn-on” response.


2017 ◽  
Vol 37 (3) ◽  
pp. 617
Author(s):  
Yong Gao ◽  
Jun Wang ◽  
Mei Fu ◽  
Hongwei Chen ◽  
Mingzhang Fang

2017 ◽  
Vol 9 (7) ◽  
pp. 1119-1124 ◽  
Author(s):  
Liqiang Yan ◽  
Renjie Li ◽  
Fulong Ma ◽  
Zhengjian Qi

A water-soluble fluorescent probe for Zn2+based on a Schiff base derivative was prepared. It displays a rapid response toward Zn2+with selectivity and sensitivity and has been successfully applied to imaging in living cells.


2021 ◽  
pp. 109371
Author(s):  
Prasad M. Sonawane ◽  
Tesla Yudhistira ◽  
Mahesh B. Halle ◽  
Arkaprava Roychaudhury ◽  
Yunsu Kim ◽  
...  

RSC Advances ◽  
2020 ◽  
Vol 10 (36) ◽  
pp. 21399-21405
Author(s):  
Chunwei Yu ◽  
Shuhua Cui ◽  
Yuxiang Ji ◽  
Shaobai Wen ◽  
Li Jian ◽  
...  

In this study, a naphthalene Schiff-base P which serves as a dual-analyte probe for the quantitative detection of Al3+ and Mg2+ has been designed.


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