Development of a cell permeable ratiometric chemosensor and biomarker for hydrogen sulphate ions in aqueous solution

RSC Advances ◽  
2014 ◽  
Vol 4 (30) ◽  
pp. 15356-15362 ◽  
Author(s):  
Buddhadeb Sen ◽  
Manjira Mukherjee ◽  
Siddhartha Pal ◽  
Sushil Kumar Mandal ◽  
Maninder S. Hundal ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Living Cells ◽  
Water Soluble ◽  
Hepes Buffer ◽  
A Cell ◽  
Hydrogen Sulphate

A newly designed benzimidazol-based water soluble ratiometric chemosensor selective for HSO4− ions behaves as an efficient biomarker for the detection of the distribution of HSO4− ions in living cells in HEPES buffer (1 mM; water : ethanol (v/v), 98 : 2).

A napthelene–pyrazol conjugate: Al(iii) ion-selective blue shifting chemosensor applicable as biomarker in aqueous solution

The Analyst ◽  
2014 ◽  
Vol 139 (19) ◽  
pp. 4828-4835 ◽  
Author(s):  
Manjira Mukherjee ◽  
Siddhartha Pal ◽  
Somenath Lohar ◽  
Buddhadeb Sen ◽  
Supriti Sen ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Living Cells ◽  
Hepes Buffer

A new crystallographically characterized napthelene–pyrazol conjugate acts as an Al(III) ion selective chemosensor in 100 mM HEPES buffer (water–DMSO 5 : 1, v/v) at biological pH. It is an efficient biomarker in detecting Al(III) ions in living cells.

Water-Soluble 8-Hydroxyquinoline Conjugate of Amino-Glucose As Receptor for La3+ in HEPES Buffer, on Whatman Cellulose Paper and in Living Cells

2015 ◽  
Vol 87 (24) ◽  
pp. 12348-12354 ◽  
Author(s):  
Sivaiah Areti ◽  
Sateesh Bandaru ◽  
Rohit Teotia ◽  
Chebrolu P. Rao
Keyword(s):  
Living Cells ◽  
Water Soluble ◽  
Hepes Buffer ◽  
Cellulose Paper

Enhanced in vitro photocytotoxicity of water-soluble dendritic pheophorbide-a

2015 ◽  
Vol 19 (07) ◽  
pp. 830-837 ◽  
Author(s):  
Eun Ji Lee ◽  
Hyoung Jun Kong ◽  
Young-Jin Kim ◽  
Jong S. Park ◽  
Myung-Seok Choi
Keyword(s):  
Aqueous Solution ◽  
Cell Death ◽  
Singlet Oxygen ◽  
Death Rate ◽  
Water Soluble ◽  
Pheophorbide A ◽  
Absorption Bands ◽  
Cell Death Rate ◽  
A Cell

Photosensitizers can produce highly reactive singlet oxygen with exposure to visible light and are used in photodynamic therapy to treat a variety of tumors. We report on the synthesis of triethylene glycol dendron-conjugated pheophorbide-a5, a novel photosensitizer. The characteristic absorption bands (Soret and Q-bands, λmax = 405 and 670 nm, respectively) of 5 were appeared clearly in aqueous solution, due to the improved water-solubility of the dendron moiety. The value of singlet oxygen quantum yield of 5 (ΦΔ = 0.22) was higher than free pheophorbide-a (ΦΔ = 0.17) as reference in aqueous solution. Compound 5 also exhibited an enhanced in vitro phototoxicity than pheophorbide-a (PhA) in the concentration range of 1.0–5.0 μg/mL: cell viability in cells treated with 5 was reduced by ~20%, indicating a cell death rate of ~80%, while PhA treatment resulted in a cell death rate of only about 10%. These results indicate that 5 will likely be more efficient in PDT applications. Compared with free PhA, compound 5 showed highly enhanced singlet oxygen generation ability and in vitro photocytotoxicity.

A water-soluble tetraphenylethene based probe for luminescent carbon dioxide detection and its biological application

2015 ◽  
Vol 3 (45) ◽  
pp. 11850-11856 ◽  
Author(s):  
Yun Ma ◽  
Yi Zeng ◽  
Hua Liang ◽  
Cheuk-Lam Ho ◽  
Qiang Zhao ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Aqueous Solution ◽  
Living Cells ◽  
Water Soluble ◽  
Porous Film ◽  
Biological Application ◽  
Carbon Dioxide Detection

A water-soluble tetraphenylethene derivative (TPE-ONa) was developed for luminescent carbon dioxide detection in aqueous solution and porous film, which is able to monitor the variation of external CO2concentration of living cells.

Enantioselective Recognition of Chiral Guests by the Water-Soluble Chiral Keplerate {Mo132} Spherical Capsule with 30 Inner Lactate Ligands

2019 ◽  
Author(s):  
Nancy Watfa ◽  
Weimin Xuan ◽  
Zoe Sinclair ◽  
Robert Pow ◽  
Yousef Abul-Haija ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Chiral Recognition ◽  
Association Constants ◽  
Water Soluble ◽  
Enantioselective Recognition ◽  
H Nmr ◽  
Dosy Nmr ◽  
Spherical Capsule ◽  
Surface Pores ◽  
Guest Chemistry

Investigations of chiral host guest chemistry are important to explore recognition in confined environments. Here, by synthesizing water-soluble chiral porous nanocapsule based on the inorganic metal-oxo Keplerate-type cluster, {Mo<sub>132</sub>} with chiral lactate ligands with the composition [Mo<sub>132</sub>O<sub>372</sub>(H<sub>2</sub>O)<sub>72</sub>(<i>x-</i>Lactate)<sub>30</sub>]<sup>42-</sup> (<i>x</i> = D or L), it was possible to study the interaction with a chiral guest, L/D-carnitine and (<i>R</i>/<i>S</i>)-2-butanol in aqueous solution. The enantioselective recognition was studied by quantitative <sup>1</sup>H NMR and <sup>1</sup>H DOSY NMR which highlighted that the chiral recognition is regulated by two distinct sites. Differences in the association constants (K) of L- and D-carnitine, which, due to their charge, are generally restricted from entering the interior of the host, are observed, indicating that their recognition predominantly occurs at the surface pores of the structure. Conversely, a larger difference in association constants (K<i><sub>S</sub></i>/K<i><sub>R</sub></i> = 3) is observed for recognition within the capsule interior of (<i>R</i>)- and (<i>S</i>)-2-butanol.

scholarly journals Sulfobetaine Cryogels for Preferential Adsorption of Methyl Orange from Mixed Dye Solutions

Polymers ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 208
Author(s):  
Ramona B. J. Ihlenburg ◽  
Anne-Catherine Lehnen ◽  
Joachim Koetz ◽  
Andreas Taubert
Keyword(s):  
Aqueous Solution ◽  
Methylene Blue ◽  
Methyl Orange ◽  
Dye Removal ◽  
Selective Adsorption ◽  
Water Soluble ◽  
Organic Substances ◽  
Preferential Adsorption ◽  
Dimethyl Ammonium ◽  
Dye Solutions

New cryogels for selective dye removal from aqueous solution were prepared by free radical polymerization from the highly water-soluble crosslinker N,N,N’,N’-tetramethyl-N,N’-bis(2-ethylmethacrylate)-propyl-1,3-diammonium dibromide and the sulfobetaine monomer 2-(N-3-sulfopropyl-N,N-dimethyl ammonium)ethyl methacrylate. The resulting white and opaque cryogels have micrometer sized pores with a smaller substructure. They adsorb methyl orange (MO) but not methylene blue (MB) from aqueous solution. Mixtures of MO and MB can be separated through selective adsorption of the MO to the cryogels while the MB remains in solution. The resulting cryogels are thus candidates for the removal of hazardous organic substances, as exemplified by MO and MB, from water. Clearly, it is possible that the cryogels are also potentially interesting for removal of other compounds such as pharmaceuticals or pesticides, but this must be investigated further.

scholarly journals A rapid “on–off–on” mitochondria-targeted phosphorescent probe for selective and consecutive detection of Cu2+ and cysteine in live cells and zebrafish

RSC Advances ◽  
2021 ◽  
Vol 11 (13) ◽  
pp. 7610-7620 ◽  
Author(s):  
Peipei Deng ◽  
Yongyan Pei ◽  
Mengling Liu ◽  
Wenzhu Song ◽  
Mengru Wang ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Living Cells ◽  
Live Cells ◽  
Mitochondria Targeting

An iridium(iii) complex-based mitochondria targeting phosphorescent probe for selectively detecting Cu2+ and Cys in aqueous solution, living cells and zebrafish has been developed.

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