A ratiometric fluorescent probe for rapid and sensitive visualization of hypochlorite in living cells

RSC Advances ◽  
2014 ◽  
Vol 4 (81) ◽  
pp. 43110-43113 ◽  
Author(s):  
Jiayu Zha ◽  
Boqiao Fu ◽  
Caiqin Qin ◽  
Lintao Zeng ◽  
Xichao Hu

A novel fluorescent probe displayed a colorimetric response to ClO− with high selectivity, fast response and a low detection limit (0.08 μM).

2016 ◽  
Vol 8 (7) ◽  
pp. 1572-1576 ◽  
Author(s):  
Xiaoming Jiang ◽  
Junchao Xu ◽  
Youlai Zhang ◽  
Hongying Wang ◽  
Lintao Zeng ◽  
...  

A colorimetric and ratiometric fluorescent probe shows a fast response and high selectivity towards sulfite with a low detection limit (12 nM).


RSC Advances ◽  
2016 ◽  
Vol 6 (21) ◽  
pp. 17059-17063 ◽  
Author(s):  
Yan-Ru Zhang ◽  
Zhi-Min Zhao ◽  
Le Su ◽  
Jun-Ying Miao ◽  
Bao-Xiang Zhao

A ratiometric fluorescent probe CRSH based on a FRET platform for detecting HOCl. CRSH showed high selectivity, excellent sensitivity and a fast response toward HOCl.


2018 ◽  
Vol 6 (30) ◽  
pp. 4903-4908 ◽  
Author(s):  
Qi Zhao ◽  
Fangjun Huo ◽  
Jin Kang ◽  
Yongbin Zhang ◽  
Caixia Yin

Herein, our group developed a fast response fluorescent probe (Flu-N3) for H2S on the basis of the 7-amino-4-methylcoumarin and fluorescein FRET system with high sensitivity and selectivity and a low detection limit of 0.031 μM. Moreover, the probe was successfully applied to image exogenous and endogenous H2S in living cells and nude mice.


2014 ◽  
Vol 50 (19) ◽  
pp. 2498-2501 ◽  
Author(s):  
Qiaoling Liu ◽  
Lixia Feng ◽  
Caixia Yuan ◽  
Lin Zhang ◽  
Shaomin Shuang ◽  
...  

A bifluorophoric probe displays high selectivity for Cd2+ and a low detection limit of 20 nM Cd2+ in aqueous solution.


2013 ◽  
Vol 295-298 ◽  
pp. 475-478 ◽  
Author(s):  
Zhi Xiang Han ◽  
Ming Hui Du ◽  
Guo Xi Liang ◽  
Xiang Yang Wu

Rhodamine B thiohydrazide (RBS) was firstly employed as turn-on fluorescent probe for hypochlorite in aqueous solution and living cells. It exhibits a stable response to hypochlorite from 1.0×10-6to 1.0×10-5M with a detection limit of 3.3×10-7M. The response of this probe to hypochlorite is fast and highly selective compared with other reactive oxygen species (such as.OH,1O2, H2O2) and other common anions (such as X-, ClO2-, ClO4-, NO3-, NO2-, OH-, Ac-, CO32-, SO42-).


2018 ◽  
Vol 42 (4) ◽  
pp. 2989-2993 ◽  
Author(s):  
Li-Jie Zhang ◽  
Jun-Ya Ning ◽  
Jun-Ying Miao ◽  
Jin-Ting Liu ◽  
Bao-Xiang Zhao

A new benzimidazole-hemicyanine-based ratiometric fluorescent probe (ZBM-H) was developed, which showed high selectivity and sensitivity for detecting HClO.


2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Xiaohua Ma ◽  
Guoguang Wu ◽  
Yuehua Zhao ◽  
Zibo Yuan ◽  
Yu Zhang ◽  
...  

We reported here a turn-on fluorescent probe (1) for the detection of cysteine (Cys) by incorporating the recognition unit of 2,4-dinitrobenzenesulfonyl ester (DNBS) to a coumarin derivative. The structure of the obtained probe was confirmed by NMR and HRMS techniques. The probe shows a remarkable fluorescence off-on response (∼52-fold) by the reaction with Cys in 100% aqueous buffer. The sensing mechanism was verified by the HPLC test. Probe 1 also displays high selectivity towards Cys. The detection limit was calculated to be 23 nM. Moreover, cellular experiments demonstrated that the probe is highly biocompatible and can be used for monitoring intracellular Cys.


2015 ◽  
Vol 39 (11) ◽  
pp. 8940-8947 ◽  
Author(s):  
Sima Paul ◽  
Shyamaprosad Goswami ◽  
Chitrangada Das Mukhopadhyay

A ratiometric fluorescent probe having a fast response and a large Stokes shift detects SH− both in solid and vapour phases and this probe is used for fluorescence imaging of SH− in living cells.


The Analyst ◽  
2015 ◽  
Vol 140 (9) ◽  
pp. 3285-3289 ◽  
Author(s):  
Fang Liu ◽  
Changqin Ding ◽  
Ming Jin ◽  
Yang Tian

A two-photon fluorescent sensor ATD was developed for Hg2+ determination with high selectivity and low detection limit, in which two-photon fluorophore TD was designed and synthesized with a specific recognition molecule for Hg2+ – PT.


2015 ◽  
Vol 44 (21) ◽  
pp. 9740-9743 ◽  
Author(s):  
Shenyi Zhang ◽  
Mei Zhao ◽  
Weiping Zhu ◽  
Yufang Xu ◽  
Xuhong Qian

A novel fluorescent probe, E3, was designed, synthesized and evaluated. It responded to Co2+ with high selectivity and sensitivity under physiological neutral conditions specifically. Furthermore, notably, probe E3 was demonstrated to detect Co2+ in living cells, indicative of its practical application potential.


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