A novel FRET-based fluorescent probe for the selective detection of hydrogen sulfide (H2S) and its application for bioimaging

2018 ◽  
Vol 6 (30) ◽  
pp. 4903-4908 ◽  
Author(s):  
Qi Zhao ◽  
Fangjun Huo ◽  
Jin Kang ◽  
Yongbin Zhang ◽  
Caixia Yin

Herein, our group developed a fast response fluorescent probe (Flu-N3) for H2S on the basis of the 7-amino-4-methylcoumarin and fluorescein FRET system with high sensitivity and selectivity and a low detection limit of 0.031 μM. Moreover, the probe was successfully applied to image exogenous and endogenous H2S in living cells and nude mice.

RSC Advances ◽  
2017 ◽  
Vol 7 (22) ◽  
pp. 13438-13443 ◽  
Author(s):  
Jiao Liu ◽  
Hong-Wei Li ◽  
Yuqing Wu

The ultrabright AuNCs@AMP are used as fluorescence probe to detect lactate dehydrogenase (LDH) with high sensitivity and selectivity, showing an extremely low detection limit of 0.2 nM (26 pg μL−1, 0.8 U L−1).


RSC Advances ◽  
2014 ◽  
Vol 4 (81) ◽  
pp. 43110-43113 ◽  
Author(s):  
Jiayu Zha ◽  
Boqiao Fu ◽  
Caiqin Qin ◽  
Lintao Zeng ◽  
Xichao Hu

A novel fluorescent probe displayed a colorimetric response to ClO− with high selectivity, fast response and a low detection limit (0.08 μM).


2018 ◽  
Vol 16 (27) ◽  
pp. 5036-5042 ◽  
Author(s):  
Lei Yang ◽  
Yuanan Su ◽  
Yani Geng ◽  
Haiqing Xiong ◽  
Jinliang Han ◽  
...  

A vinethene-based fluorescent probe has been developed for the sensitive and selective detection of Hg2+ with a low detection limit, a red emission and a large Stokes shift. The probe has been successfully applied to detect Hg2+ in aqueous solutions, living cells and organisms.


RSC Advances ◽  
2021 ◽  
Vol 11 (16) ◽  
pp. 9290-9295
Author(s):  
Yihua Zhuo ◽  
Yanyu Zhang ◽  
Yadong Feng ◽  
Yuqing Xu ◽  
Qihua You ◽  
...  

A highly selective OFF–ON fluorescent probe has been developed for the sensing of biothiols with a satisfactory response time and low detection limit. Also, the probe can be successfully applied for the sensing of biothiols in living cells.


2016 ◽  
Vol 52 (38) ◽  
pp. 6415-6418 ◽  
Author(s):  
Mingguang Ren ◽  
Beibei Deng ◽  
Xiuqi Kong ◽  
Kai Zhou ◽  
Keyin Liu ◽  
...  

Through rational design, the first TICT based fluorescent H2S probe was developed, which exhibited ideal properties such as fast response, good selectivity, high sensitivity, and it was suitable for visualization of exogenous and endogenous H2S in living cells.


2013 ◽  
Vol 823 ◽  
pp. 291-295 ◽  
Author(s):  
Shou Chen Chai ◽  
Peng Yang ◽  
Cheng Jia Yang ◽  
Chun Li Cai ◽  
Na Yu

In the space restricted airtight environment that people lives in, detecting harmful gas by miniature gas chromatography is the practical requirement at present, however, PIDs performance is key factor that restrict the application of miniature gas chromatography, the redesign of the detectors gas route in this paper aiming at improve detectors stability observably, and schemed out miniature PID with high sensitivity, low detection limit and fast response. The result of the experiment shows that the detection limit is 0.04ppm, the sensitivity is 101mv/ppm,the stability is 0.04×10-6/24h,meeting the project requirement. Keywords: photoionization detector; ionization chamber; sensitivity; detection limit;


2016 ◽  
Vol 232 ◽  
pp. 619-624 ◽  
Author(s):  
Tao Liu ◽  
Fangjun Huo ◽  
Jianfang Li ◽  
Jianbin Chao ◽  
Yongbin Zhang ◽  
...  

The Analyst ◽  
2020 ◽  
Vol 145 (6) ◽  
pp. 2305-2310 ◽  
Author(s):  
Ruqiao Zhou ◽  
Guiling Cui ◽  
Qingrong Qi ◽  
Wencai Huang ◽  
Li Yang

Hydrogen sulfide (H2S), a well-known poisonous gas, has been recognized as a critical endogenous gas transmitter in the past decade.


RSC Advances ◽  
2015 ◽  
Vol 5 (119) ◽  
pp. 98154-98159 ◽  
Author(s):  
Liu Yang ◽  
Xingjiang Liu ◽  
Li Gao ◽  
Fengpei Qi ◽  
Huihui Tian ◽  
...  

A phthalimide-based fluorescent probe for H2S with a large Stokes shift has been developed. This probe displayed good selectivity and high sensitivity. Imaging intracellular H2S by using this probe was successfully achieved in living cells.


RSC Advances ◽  
2016 ◽  
Vol 6 (71) ◽  
pp. 66774-66778 ◽  
Author(s):  
Prithidipa Sahoo ◽  
Himadri Sekhar Sarkar ◽  
Sujoy Das ◽  
Kalipada Maiti ◽  
Md Raihan Uddin ◽  
...  

A new ‘turn-ON’ fluorescent probe, pyrene appended thymine acetamide (PTA), with high sensitivity and selectivity for the detection of uric acid (UA) was developed and first time imaging of uric acid in living cells in water was achieved.


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