Oligonucleotide-stabilized fluorescent silver nanoclusters for the specific and sensitive detection of biotin

The Analyst ◽  
2016 ◽  
Vol 141 (4) ◽  
pp. 1499-1505 ◽  
Author(s):  
Xiaoli Xiong ◽  
Yan Tang ◽  
Jingjin Zhao ◽  
Shulin Zhao

A novel biotin fluorescent probe based on oligonucleotide-stabilized silver nanoclusters (DNA-AgNCs) was synthesized by employing a biotinylated cytosine-rich sequence as a synthesized template.


2014 ◽  
Vol 202 ◽  
pp. 631-637 ◽  
Author(s):  
Zhen Chen ◽  
Dongtao Lu ◽  
Guomei Zhang ◽  
Jun Yang ◽  
Chuan Dong ◽  
...  


Sensors ◽  
2017 ◽  
Vol 17 (2) ◽  
pp. 405 ◽  
Author(s):  
Zi-Hua Zheng ◽  
Zhi-Ke Li ◽  
Lin-Jiang Song ◽  
Qi-Wei Wang ◽  
Qing-Fei Huang ◽  
...  




2021 ◽  
Vol MA2021-01 (63) ◽  
pp. 1680-1680
Author(s):  
Anshu Kumar ◽  
Prathul Nath ◽  
Vishal Kumar ◽  
Soumitra Satapathi


Talanta ◽  
2019 ◽  
Vol 195 ◽  
pp. 472-479 ◽  
Author(s):  
Xiaoping Tan ◽  
Yue Wu ◽  
Sha Yu ◽  
Tingying Zhang ◽  
Hexiang Tian ◽  
...  


Molecules ◽  
2018 ◽  
Vol 23 (10) ◽  
pp. 2679 ◽  
Author(s):  
Yibin Zhang ◽  
Jianheng Bi ◽  
Shuai Xia ◽  
Wafa Mazi ◽  
Shulin Wan ◽  
...  

A fluorescence resonance energy transfer (FRET)-based near-infrared fluorescent probe (B+) for double-checked sensitive detection of intracellular pH changes has been synthesized by binding a near-infrared rhodamine donor to a near-infrared cyanine acceptor through robust C-N bonds via a nucleophilic substitution reaction. To demonstrate the double-checked advantages of probe B+, a near-infrared probe (A) was also prepared by modification of a near-infrared rhodamine dye with ethylenediamine to produce a closed spirolactam residue. Under basic conditions, probe B+ shows only weak fluorescence from the cyanine acceptor while probe A displays nonfluorescence due to retention of the closed spirolactam form of the rhodamine moiety. Upon decrease in solution pH level, probe B+ exhibits a gradual fluorescence increase from rhodamine and cyanine constituents at 623 nm and 743 nm respectively, whereas probe A displays fluorescence increase at 623 nm on the rhodamine moiety as acidic conditions leads to the rupture of the probe spirolactam rings. Probes A and B+ have successfully been used to monitor intracellular pH alternations and possess pKa values of 5.15 and 7.80, respectively.







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