scholarly journals Improvements in Cd stable isotope analysis achieved through use of liquid–liquid extraction to remove organic residues from Cd separates obtained by extraction chromatography

2016 ◽  
Vol 31 (1) ◽  
pp. 319-327 ◽  
Author(s):  
Katy Murphy ◽  
Mark Rehkämper ◽  
Katharina Kreissig ◽  
Barry Coles ◽  
Tina van de Flierdt
Keyword(s):  
Isotope Analysis ◽  
Extraction Procedure ◽  
Isotopic Analysis ◽  
Liquid Extraction ◽  
Organic Residues ◽  
Mass Fractionation ◽  
Liquid Liquid Extraction ◽  
Icp Ms ◽  
Organic Resin ◽  
Instrumental Mass Fractionation

During isotopic analysis of Cd by MC-ICP-MS, organic resin residue can perturb instrumental mass fractionation. These organic compounds can be removed by a liquid–liquid extraction procedure using heptane.

Quantitation and Confirmation of Chloramphenicol, Florfenicol, and Nitrofuran Metabolites in Honey Using LC-MS/MS

2018 ◽  
Vol 101 (3) ◽  
pp. 897-903 ◽  
Author(s):  
Brian T Veach ◽  
Renea Anglin ◽  
Thilak K Mudalige ◽  
Paula J Barnes
Keyword(s):  
Extraction Procedure ◽  
Extraction Methods ◽  
Liquid Extraction ◽  
Tandem Ms ◽  
Robust Method ◽  
Calibration Standards ◽  
Single Extraction ◽  
Liquid Liquid Extraction ◽  
Lc Tandem Ms ◽  
Nitrofuran Metabolites

Abstract This paper describes a rapid and robust method utilizing a single liquid–liquid extraction for the quantitation and confirmation of chloramphenicol, florfenicol, and nitrofuran metabolites in honey. This methodology combines two previous extraction methods into a single extraction procedure and utilizes matrix-matched calibration standards and stable isotopically labeled standards to improve quantitation. The combined extraction procedure reduces the average extraction time by >50% when compared with previously used procedures. The drug residues were determined using two separate LC-tandem MS conditions. Validation of all the analytes was performed, with average quantitation ranging from 92 to 105% for all analytes and the RSDs for all analytes being ≤12%.

scholarly journals Residue of ochratoxin a in chicken tissues-risk assessment

2011 ◽  
Vol 19 (1-2) ◽  
pp. 23-27 ◽  
Author(s):  
Dragan Milicevic ◽  
Milijan Jovanovic ◽  
Vesna Matekalo-Sverak ◽  
Tatjana Radicevic ◽  
Milan Petrovic ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Extraction Procedure ◽  
Maximum Level ◽  
Liquid Extraction ◽  
Preliminary Evaluation ◽  
Retail Market ◽  
Tissue Samples ◽  
Chicken Tissues ◽  
Liquid Liquid Extraction ◽  
Agricultural Areas

Background: Toxicological investigations of tissues of normally slaughtered chickens were carried out to provide preliminary evaluation of the incidence of OTA in chicken tissues (n=90). Majority of tissue samples were not found to contain measurable amounts of OTA, while in general, the OTA levels found in the analyzed tissue were low. Methods: The presence of OTA in tissue samples was determined by HPLC-FL after liquid-liquid extraction procedure. Method validation was performed according to the Commission Decision 2002/657/EC. Results: Of the 90 liver, kidney and gizzard samples originating from chicken farms located in the different agricultural areas of Serbia, OTA was reported in 23 (38.33%), 17 (28.3%) and 16 (26.6%) samples, respectively, with levels ranging from 0.14 to 3.9 ng/g in liver, 0.1 to 7.02 ng/g in kidneys and 0.25 to 9.94 ng/g in gizzard. None of the tissue samples contained more than the maximum level (10 ng/g) recommended by the European Commission. Conclusion: Low OTA results also suggested that chicken meat available in the retail market is unlikely to pose an adverse health risk to the consumers in respect to OTA toxicity.

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