Moxifloxacin-capped noble metal nanoparticles as potential urease inhibitors

2015 ◽  
Vol 39 (10) ◽  
pp. 8080-8086 ◽  
Author(s):  
Muhammad Nisar ◽  
Shujaat Ali Khan ◽  
Muhammad Raza Shah ◽  
Ajmal Khan ◽  
Umar Farooq ◽  
...  

The fluoroquinolone drug moxifloxacin (Mox) has been used to protect silver and gold nanoparticles. The nano-conjugates exhibited urease inhibition and antibacterial activity.

2018 ◽  
Vol 20 (4) ◽  
pp. 2676-2692 ◽  
Author(s):  
Joakim Halldin Stenlid ◽  
Adam Johannes Johansson ◽  
Tore Brinck

Using local DFT-based probes for electrostatic as well as charge transfer/polarization interactions, we are able to characterize Lewis basic and acidic sites on copper, silver and gold nanoparticles.


2020 ◽  
Vol 4 (2) ◽  

Metal nanoparticles possess an extensive scientific and technological significance due to their unique physiochemical properties and their potential applications in different fields like medicine. Silver and gold nanoparticles have shown to have antibacterial and cytotoxic activities. Conventional methods used in the synthesis of the metal nanoparticles involve use of toxic chemicals making them unsuitable for use in medical field. In our continued effort to explore for simple and eco-friendly methods to synthesize the metal nanoparticles, we here describe synthesis and characterization of gold and silver nanoparticles using Gonaderma lucidum, wild non-edible medicinal mushroom. G. lucidum mushroom contain bioactive compounds which can be involved in the reduction, capping and stabilization of the nanoparticles. Antibacterial activity analysis was done on E. coli and S. aureus. The synthesis was done on ultrasonic bath. Characterization of the metal nanoparticles was done by UV-VIS., High Resolution Transmission Electron Microscope (HRTEM) and FTIR. HRTEM analysis showed that both silver and gold nanoparticles were spherical in shape with an average size of 15.82±3.69 nm for silver and 24.73±5.124nm for gold nanoparticles (AuNPs). FTIR analysis showed OH and -C=C- stretching vibrations, an indication of presence of functional groups of biomolecules capping both gold and silver nanoparticles. AgNPs showed inhibition zones of 15.5±0.09mm and 13.3±0.14mm while AuNPs had inhibition zones of 14.510±0.35 and 13.3±0.50mm on E. coli and S. aureus respectively. The findings indicate the potential use of AgNPs and AuNPs in development of drugs in management of pathogenic bacteria.


RSC Advances ◽  
2018 ◽  
Vol 8 (70) ◽  
pp. 40454-40463 ◽  
Author(s):  
Diamela María Rocca ◽  
Julie P. Vanegas ◽  
Kelsey Fournier ◽  
M. Cecilia Becerra ◽  
Juan C. Scaiano ◽  
...  

Natural derived compounds, lignins, can be used as reducing and stabilizing agents to synthesize noble metal nanoparticles with antimicrobial properties.


Materials ◽  
2021 ◽  
Vol 14 (20) ◽  
pp. 5976
Author(s):  
Kyoung-Suk Moon ◽  
Young-Bum Park ◽  
Ji-Myung Bae ◽  
Eun-Joo Choi ◽  
Seung-Han Oh

The visible light reactions of noble metal-based photocatalysts have been increasingly utilized to investigate their antibacterial activities. Furthermore, the photoreactions at various visible light wavelengths for specific combinations of titania nanotubes and noble metal nanoparticles have been found to promote osteogenic functionality. In this investigation, a novel multi-coating combination of noble metals (gold and platinum) on titania nanotubes was assessed using plasmonic photocatalysis and low-level laser therapy at 470 and 600 nm. The results showed that this coating on the nanotubes promoted antibacterial activity and osteogenic functionality. The order in which the gold and platinum coatings were layered onto the titania nanotubes strongly affected the osteogenic performance of the human mesenchymal stem cells. These results have identified a new approach for the development of efficient novel combinations of noble metal nanoparticles and titania nanotubes with visible light responses, sustainable antimicrobial activity, and osteogenic functionality.


RSC Advances ◽  
2014 ◽  
Vol 4 (86) ◽  
pp. 46285-46292 ◽  
Author(s):  
Soumen Das ◽  
Basab Bijayi Dhar

Noble metal nanoparticles (NPs) have shown remarkable potential for numerous applications.


2019 ◽  
Vol 21 (34) ◽  
pp. 18753-18757 ◽  
Author(s):  
Qipeng Lu ◽  
Lijie Zhu ◽  
Sumei Han ◽  
Yanbing Hou ◽  
Wenbin Cao

Herein, we investigate the mechanism of photocatalytic synthesis of noble metal nanoparticles by reductive photoelectrons generated from semiconductors.


2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Van Thuan Le ◽  
Ngoc Nhu Quynh Ngu ◽  
Tan Phat Chau ◽  
Thi Dung Nguyen ◽  
Van Toan Nguyen ◽  
...  

This study describes a simple green method for the synthesis of Limnophila rugosa leaf-extract-capped silver and gold nanoparticles without using any expensive toxic reductant or stabilizer. The noble metal nanoparticles were characterized by Fourier transform infrared (FTIR) microscopy, powder X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), energy-dispersive X-ray analysis (EDX), high-resolution transmission electron microscopy (HR-TEM), selected area electron diffraction (SAED), and dynamic light scattering (DLS) method. It has been found that the biosynthesized silver and gold nanoparticles are nearly spherical in shape with a mean particle size distribution of 87.5 nm and 122.8 nm, respectively. XRD and SAED patterns confirmed the crystalline nanostructure of the metal nanoparticles. FTIR spectra revealed the functional groups of biomolecules presented in the extract possibly responsible for reducing metallic ions and stabilizing formed nanoparticles. The biosynthesized metal nanoparticles have potential application in catalysis. Compared to previous reports, Limnophila rugosa leaf-extract-capped silver and gold nanoparticles exhibited a good catalytic activity in the reduction of several derivatives of nitrophenols including 1,4-dinitrobenzene, 2-nitrophenol, 3-nitrophenol, and 4-nitrophenol.


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