Tannin as a gatekeeper of pH-responsive mesoporous silica nanoparticles for drug delivery

RSC Advances ◽  
2015 ◽  
Vol 5 (104) ◽  
pp. 85436-85441 ◽  
Author(s):  
Chunlin Hu ◽  
Lingxue Yu ◽  
Zhen Zheng ◽  
Jing Wang ◽  
Yuan Liu ◽  
...  

Tannin grafted on mesoporous silica nanoparticles (tannin-MSNs) was synthesized by the amidation reaction of carboxyl benzyl borate with amino group modified MSN.

MedChemComm ◽  
2017 ◽  
Vol 8 (9) ◽  
pp. 1797-1805 ◽  
Author(s):  
Madhappan Santha Moorthy ◽  
Subramanian Bharathiraja ◽  
Panchanathan Manivasagan ◽  
Kang Dae Lee ◽  
Junghwan Oh

Herein, we propose a “host–guest” complexation-based mesoporous silica drug carrier, MSNs@Mela@TTM, for pH-responsive drug delivery applications in cancer therapy.


2015 ◽  
Vol 44 (46) ◽  
pp. 20186-20192 ◽  
Author(s):  
Haoquan Zheng ◽  
Cheuk-Wai Tai ◽  
Jie Su ◽  
Xiaodong Zou ◽  
Feifei Gao

A pH-responsive drug delivery system via mesoporous silica nanoparticles as carriers can be achieved based on electrostatic interactions between drug molecules and carriers, when the isoelectric point of the drug molecule is high.


Nanoscale ◽  
2015 ◽  
Vol 7 (16) ◽  
pp. 7178-7183 ◽  
Author(s):  
Isurika R. Fernando ◽  
Daniel P. Ferris ◽  
Marco Frasconi ◽  
Dmitry Malin ◽  
Elena Strekalova ◽  
...  

Gating of mesoporous silica nanoparticles (MSNs) with the stimuli-responsive poly(β-amino ester) has been achieved.


Nanoscale ◽  
2016 ◽  
Vol 8 (47) ◽  
pp. 19573-19580 ◽  
Author(s):  
Hongbo Gao ◽  
Xiaohang Liu ◽  
Wei Tang ◽  
Dechao Niu ◽  
Bingni Zhou ◽  
...  

Langmuir ◽  
2016 ◽  
Vol 32 (47) ◽  
pp. 12453-12460 ◽  
Author(s):  
Yang Yang ◽  
Katharina Achazi ◽  
Yi Jia ◽  
Qiang Wei ◽  
Rainer Haag ◽  
...  

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