Microwave-assisted expeditious and efficient synthesis of novel quinolin-4-ylmethoxychromen-2- and -4-ones catalyzed by YbCl3 under a solvent free one-pot three component domino reaction and their antimicrobial activity

RSC Advances ◽  
2015 ◽  
Vol 5 (113) ◽  
pp. 93067-93080 ◽  
Author(s):  
Sumit Kumar ◽  
Alok Patel ◽  
Naseem Ahmed
Keyword(s):  
Antimicrobial Activity ◽  
Solvent Free ◽  
Domino Reaction ◽  
Efficient Synthesis ◽  
One Pot ◽  
Microwave Assisted ◽  
High Yields

MW assisted multicomponent A3 synthesis was developed for the synthesis of quinolin-4-ylmethoxychromen-2- and -4-ones in high yields with YbCl3 and reused efficiently for four times.

1,3-Dibromo-5,5-dimethylhydantoin as a useful reagent for efficient synthesis of 3,4-dihydropyrimidin-2-(1H)-ones under solvent-free conditions

2009 ◽  
Vol 63 (1) ◽  
Author(s):  
Mohammad Abdollahi-Alibeik ◽  
Zahra Zaghaghi
Keyword(s):  
Microwave Irradiation ◽  
Ethyl Acetoacetate ◽  
Biginelli Reaction ◽  
Reaction Times ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
One Pot ◽  
Aliphatic Aldehydes ◽  
Solvent Free Conditions ◽  
High Yields

AbstractEfficient syntheses of 3,4-dihydropyrimidin-2-(1H)-ones and the corresponding thioxo derivatives using 1,3-dibromo-5,5-dimethylhydantoin (DBH) catalysis of a one-pot three-component Biginelli reaction of aldehydes, ethyl acetoacetate, and urea or thiourea under microwave irradiation are described. The advantages of this method are its short reaction times, high yields of the products, inexpensive and commercially available catalyst, and solvent-free conditions. Typical isolated yields exceed 70 % for arylaldehydes (9 examples) and aliphatic aldehydes (2 examples).

scholarly journals Efficient Synthesis of 1-Amidoalkyl-2-Naphthols by One-Pot, Three-Component Reaction under Solvent-Free Conditions

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Zahed Karimi-Jaberi ◽  
Marziyeh Jokar ◽  
S. Zoleykha Abbasi
Keyword(s):  
Trichloroacetic Acid ◽  
Reaction Times ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
One Pot Condensation ◽  
High Yields ◽  
Free Media

Two efficient and direct procedures have been developed for the preparation of 1-amidoalkyl-2-naphthols by a one-pot condensation of aldehydes, 2-naphthol, and amides in the presence of trichloroacetic acid or cobalt (II) chloride as catalyst. The reactions were carried out under solvent-free media. High yields, short reaction times, easy workup of the catalyst are advantages of these procedures.

Microwave-Assisted Efficient synthesis of Dihydro Pyrimidines: Improved High Yielding Protocol for the Biginelli Reaction

2000 ◽  
Vol 2000 (7) ◽  
pp. 354-355 ◽  
Author(s):  
J.S. Yadav ◽  
B.V. Subba Reddy ◽  
E. Jagan Reddy ◽  
T. Ramalingam
Keyword(s):  
Acetic Acid ◽  
Microwave Irradiation ◽  
Biginelli Reaction ◽  
Acid Catalysts ◽  
Efficient Synthesis ◽  
One Pot ◽  
Amberlyst 15 ◽  
Microwave Assisted ◽  
Cyclocondensation Reaction ◽  
High Yields

Dihydropyrimidines were synthesised in high yields by one-pot cyclocondensation reaction of aldehydes, aceto-acetates and urea using various acid catalysts like Amberlyst-15, Nafion-H, KSF clay and dry acetic acid under microwave irradiation.

scholarly journals Microwave Assisted Solvent Free Synthesis of Azomethines from Aryl Aldehydes on Melamin Formaldehyde as Solid Support

2011 ◽  
Vol 8 (3) ◽  
pp. 1142-1145 ◽  
Author(s):  
Ramin Rezaei ◽  
Mohammad K. Mohammadi ◽  
Tahereh Ranjbar
Keyword(s):  
Microwave Irradiation ◽  
Hydroxylamine Hydrochloride ◽  
Solid Support ◽  
Solvent Free ◽  
Melamine Formaldehyde ◽  
One Pot ◽  
Aryl Aldehydes ◽  
Microwave Assisted ◽  
High Yields ◽  
Solvent Free Synthesis

Various aryl aldehydes underwent prompt one pot conversion into the corresponding azomethines in high yields by reacting with hydroxylamine hydrochloride supported on melamine formaldehyde under microwave irradiation.

scholarly journals N-Bromosuccinimide Catalyzed Three Component One-Pot Efficient Synthesis of 2,4,5-Triaryl-1H-imidazoles from Aldehyde, Ammonium Acetate, and 1,2-Diketone or α-Hydroxyketone

2017 ◽  
Vol 58 (1) ◽  
Author(s):  
Behrooz Maleki ◽  
Samaneh Sedigh Ashrafi
Keyword(s):  
Present Method ◽  
Ammonium Acetate ◽  
Reaction Times ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
One Pot ◽  
Environmental Friendliness ◽  
Solvent Free Condition ◽  
Solvent Free Conditions ◽  
High Yields

<p>A simple, green, and efficient method for the synthesis of 2,4,5-triaryl-1<em>H</em>-imidazoles using <em>N</em>-bromosuccinimide (NBS) as a catalyst under solvent-free condition is described. The major advantages of the present method are: high yields, less reaction times, solvent-free conditions, easy purification of the products, environmental friendliness, and convenient operation.</p>

scholarly journals H2SO4-Silica Catalyzed One-Pot and Efficient Synthesis of Dihydropyrimidinones Under Solvent-Free Conditions

2011 ◽  
Vol 8 (s1) ◽  
pp. S462-S466 ◽  
Author(s):  
Seied Ali Pourmousavi ◽  
Maryam Hasani
Keyword(s):  
Condensation Reaction ◽  
Biginelli Reaction ◽  
Reaction Times ◽  
Solvent Free ◽  
New Method ◽  
Efficient Synthesis ◽  
Reaction Conditions ◽  
One Pot ◽  
Solvent Free Conditions ◽  
High Yields

H2SO4-Silica efficiently catalyzes the three-component condensation reaction of aldehydes, 1,3-dicarbonyl compounds and urea/thiourea under solvent free conditions to afford the corresponding dihydropyrimidinones and thio-derivatives in high yields. Compared to the classical Biginelli reaction conditions, this new method consistently has the advantage of giving good yields and requiring short reaction times.

scholarly journals Microwave-Assisted Efficient Synthesis of Spiropyridine Derivatives via Catalyst- and Solvent-Free One Pot Four Component Reaction

2020 ◽  
Vol 33 (1) ◽  
pp. 103-107
Author(s):  
Debajyoti Bhuyan
Keyword(s):  
Aromatic Aldehyde ◽  
Barbituric Acid ◽  
Ammonium Acetate ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
One Pot ◽  
Microwave Assisted ◽  
Solvent Free Conditions

A microwave-assisted, one-pot four-component reaction strategy has been developed for the synthesis of some novel spiropyridine derivatives from 1,3-dimethyl barbituric acid, chalcone, aromatic aldehyde and ammonium acetate under catalyst- and solvent-free conditions.

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