A near-infrared fluorescent aza-bodipy probe for dual-wavelength detection of hydrogen peroxide in living cells

The Analyst ◽  
2016 ◽  
Vol 141 (8) ◽  
pp. 2380-2383 ◽  
Author(s):  
Jingjing Xu ◽  
Jingying Zhai ◽  
Yanmei Xu ◽  
Jingwei Zhu ◽  
Yu Qin ◽  
...  

A boronic acid functionalized aza-borondipyrromethene dye (azaBDPBA) was applied to the dual-wavelength detection of hydrogen peroxide with high selectivity, which was loaded into cells to indicate the alteration of intracellular hydrogen peroxide during biological processes.

RSC Advances ◽  
2016 ◽  
Vol 6 (92) ◽  
pp. 89940-89943 ◽  
Author(s):  
Fuxu Zhan ◽  
Qian Yang ◽  
Qiufen Wang ◽  
Qilong Zhang ◽  
Zhiyuan Zhuang ◽  
...  

An extremely rapid-response fluorescent probe for H2O2was constructed for monitoring the H2O2levels in biological processes.


RSC Advances ◽  
2016 ◽  
Vol 6 (43) ◽  
pp. 36906-36909 ◽  
Author(s):  
Bin Wang ◽  
Na Jiang ◽  
Wei Sun ◽  
Qiufen Wang ◽  
Gengxiu Zheng

A near-infrared ratiometric fluorescence probe, BOC, was developed for detection of H2S. The probe features high selectivity and sensitivity. And BOC has the ability to detect H2S in living cells.


2020 ◽  
Author(s):  
Qian WU ◽  
Youmei Li ◽  
Ying Li ◽  
Dong Wang ◽  
Ben Zhong Tang

Hydrogen peroxide (H2O2), as one kind of key reactive oxygen species (ROS), is mainly produced endogenously primarily in the mitochondria. The selective monitoring of H2O2 in living cells is of great significance for understanding diagnosis and pathogenesis of cancers, the Alzheimer’s disease and diabetes. Here, we constructed a versatile AIE probe, TTPy-H2O2, which achieved superb performances in the specifically visualization of H2O2 specifically in various living cells with mitochondria targeting, excellent biocompatibility and photostability, and remarkable ROS generation ability. Red/near-infrared fluorescence firstly located in the mitochondria could light up lipid droplets with bright yellow fluorescence after responding to the H2O2, which can realize both imaging and photodynamic therapy (PDT) for cancer therapy. <br>


RSC Advances ◽  
2020 ◽  
Vol 10 (45) ◽  
pp. 26874-26879 ◽  
Author(s):  
Xueyuan Bi ◽  
Yingying Wang ◽  
Dandan Wang ◽  
Liming Liu ◽  
Wen Zhu ◽  
...  

A lower pH level and high hydrogen peroxide (H2O2) concentration in mitochondria is closely associated with a variety of diseases including cancer and inflammation.


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