A near-infrared, colorimetric and ratiometric fluorescent sensor with high sensitivity to hydrogen peroxide and viscosity for solutions detection and imaging living cells

2021 ◽  
pp. 105513
Author(s):  
Daili Liu ◽  
Gaofei Chen ◽  
Guiqian Fang
2013 ◽  
Vol 17 (01n02) ◽  
pp. 99-103 ◽  
Author(s):  
Hui He ◽  
Jian-Yong Liu ◽  
Dennis K.P. Ng

This paper describes the preparation and spectral properties of a near-infrared fluorophore in which two bis(2-picolyl)amino moieties are axially linked to a silicon(IV) phthalocyanine core. The effects of various metal ions on its absorption and fluorescence spectra have been examined. The results indicate that this compound shows a high sensitivity and moderate selectivity toward Zn2+ ion.


2017 ◽  
Vol 94 ◽  
pp. 24-29 ◽  
Author(s):  
Huatang Zhang ◽  
Ling Feng ◽  
Yin Jiang ◽  
Yin-Ting Wong ◽  
Yonghe He ◽  
...  

2019 ◽  
Vol 43 (24) ◽  
pp. 9614-9622
Author(s):  
Ming Qian ◽  
Liuwei Zhang ◽  
Jingyun Wang

Probe N-Bio exhibited rapid response, high sensitivity and strong NIR fluorescence in the detection of biothiols in living cells.


The Analyst ◽  
2016 ◽  
Vol 141 (8) ◽  
pp. 2380-2383 ◽  
Author(s):  
Jingjing Xu ◽  
Jingying Zhai ◽  
Yanmei Xu ◽  
Jingwei Zhu ◽  
Yu Qin ◽  
...  

A boronic acid functionalized aza-borondipyrromethene dye (azaBDPBA) was applied to the dual-wavelength detection of hydrogen peroxide with high selectivity, which was loaded into cells to indicate the alteration of intracellular hydrogen peroxide during biological processes.


Sensors ◽  
2020 ◽  
Vol 20 (17) ◽  
pp. 4768 ◽  
Author(s):  
Zongcheng Wang ◽  
Huihuang Zheng ◽  
Chengliang Zhang ◽  
Dongfang Tang ◽  
Qiyao Wu ◽  
...  

The content of selenocysteine in cells has an important effect on a variety of human diseases, and the detection of selenocysteine by fluorescent sensors in vivo has shown many advantages. In order to further develop fast-reaction-time, good-selectivity, and high-sensitivity long-wavelength selenocysteine fluorescent sensors, we designed and synthesized the compound YZ-A4 as a turn-on fluorescent sensor to detect the content of selenocysteine. The quantitative detection range of the sensor YZ-A4 to selenocysteine was from 0 to 32 μM, and the detection limit was as low as 11.2 nM. The sensor displayed a rapid turn-on response, good selectivity, and high sensitivity to selenocysteine. Finally, we have demonstrated that YZ-A4 could be used for fluorescence imaging of selenocysteine in living cells.


Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3352
Author(s):  
Yingying Zuo ◽  
Yang Jiao ◽  
Chunming Ma ◽  
Chunying Duan

Hydrogen peroxide (H2O2) plays an important role in the human body and monitoring its level is meaningful due to the relationship between its level and diseases. A fluorescent sensor (CMB) based on coumarin was designed and its ability for detecting hydrogen peroxide by fluorescence signals was also studied. The CMB showed an approximate 25-fold fluorescence enhancement after adding H2O2 due to the interaction between the CMB and H2O2 and had the potential for detecting physiological H2O2. It also showed good biocompatibility and permeability, allowing it to penetrate cell membranes and zebrafish tissues, thus it can perform fluorescence imaging of H2O2 in living cells and zebrafish. This probe is a promising tool for monitoring the level of H2O2 in related physiological and pathological research.


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