Different pH triggered aggregate morphologies in sodium oleate–cationic surfactants mixed systems

Malonyl-CoA inhibition of carnitine palmitoyltransferase I was found to be very pH-dependent. Malonyl-CoA concentrations causing 50% inhibition (I50) at pH 6.0, 6.5, 7.0, 7.5 and 8.0 were 0.04, 1, 9, 40 and 200 microM respectively. It is suggested that a lowering of intracellular pH, such as might occur in ketoacidosis, may attenuate hepatic fatty acid oxidation by increasing malonyl-CoA sensitivity of carnitine palmitoyltransferase I.

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The effect of pH dependent molecular conformation and dimerization phenomena of piroxicam on the drug:cyclodextrin complex stoichiometry and its chromatographic behaviour

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2004.01.007 ◽

2004 ◽

Vol 21 (5) ◽

pp. 661-669 ◽

Cited By ~ 31

Author(s):

Stavroula Rozou ◽

Afrodite Voulgari ◽

Ekaterini Antoniadou-Vyza

Keyword(s):

Molecular Conformation ◽

Effect Of Ph ◽

Chromatographic Behaviour ◽

Complex Stoichiometry ◽

Ph Dependent

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Self-assembly of mixed systems based on nonionic and carbamate-bearing cationic surfactants as a tool for fabrication of biocompatible nanocontainers

Journal of Molecular Liquids ◽

10.1016/j.molliq.2019.111407 ◽

2019 ◽

Vol 292 ◽

pp. 111407 ◽

Cited By ~ 15

Author(s):

Alla B. Mirgorodskaya ◽

Rushana A. Kushnazarova ◽

Svetlana S. Lukashenko ◽

Lucia Ya. Zakharova

Keyword(s):

Self Assembly ◽

Cationic Surfactants ◽

Mixed Systems

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Adsorption of DL-alanine by allophane: effect of pH and unit particle aggregation

Clay Minerals ◽

10.1180/000985599546190 ◽

1999 ◽

Vol 34 (2) ◽

pp. 233-238 ◽

Cited By ~ 9

Author(s):

H. Hashizume ◽

B. K. G. Theng

Keyword(s):

Adsorption Isotherms ◽

Linear Increase ◽

Particle Aggregation ◽

Published Data ◽

Effect Of Ph ◽

Linear Rise ◽

Equilibrium Concentrations ◽

Ph Dependent ◽

High Concentrations

AbstractThe adsorption of DL-alanine at pH 4, 6 and 8 by a soil allophane has been determined. Two sets of experiments were carried out: (1) in which the allophane had been kept in a moist state throughout; and (2) in which the mineral had previously been dried at 50°C. In both instances, the adsorption isotherms showed three distinct regions as the concentration of alanine in solution was increased: (1) an initial, nearly linear, rise at low equilibrium concentrations; (2) a levelling off to a plateau at intermediate concentrations; and (3) a steep linear increase at high concentrations. For comparable concentrations of alanine in solution, adsorption decreased in the order pH 6 > pH 8 > pH 4. Irrespective of pH, however, more alanine was adsorbed by the ‘wet’ allophane than by its ‘dry’ counterpart. These observations are interpreted in terms of the morphology and aggregation of allophane unit particles together with the pH-dependent charge characteristics of allophane and alanine. The results are compared with published data on the adsorption of alanine by montmorillonite.

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