Synthesis and self-assembly behaviour of poly(Nα-Boc-l-tryptophan)-block-poly(ethylene glycol)-block-poly(Nα-Boc-l-tryptophan)

RSC Advances ◽  
2016 ◽  
Vol 6 (29) ◽  
pp. 24142-24153
Author(s):  
Andreea S. Voda ◽  
Kevin Magniez ◽  
Nisa V. Salim ◽  
Cynthia Wong ◽  
Qipeng Guo

We report for the first time the use of Nα-Boc-l-tryptophan for the synthesis of amphiphilic BAB triblock copolymers for potential drug delivery applications.

2017 ◽  
Vol 170 ◽  
pp. 166-175 ◽  
Author(s):  
Lisa Racine ◽  
Guillaume Costa ◽  
Eric Bayma-Pecit ◽  
Isabelle Texier ◽  
Rachel Auzély-Velty

RSC Advances ◽  
2015 ◽  
Vol 5 (79) ◽  
pp. 64170-64179 ◽  
Author(s):  
Jing Song ◽  
Qun Ye ◽  
Wang Ting Lee ◽  
Xiaobai Wang ◽  
Tao He ◽  
...  

A series of perfluoropolyether/poly(ethylene glycol) (PFPE/PEG) triblock copolymers PEG/PFPE/PEG (P1–P3) and PFPE/PEG/PFPE (P4–P5) were prepared via thiol–ene click reaction in high yields.


RSC Advances ◽  
2016 ◽  
Vol 6 (63) ◽  
pp. 58160-58172 ◽  
Author(s):  
Y. Chen ◽  
Y. X. Zhang ◽  
Z. F. Wu ◽  
X. Y. Peng ◽  
T. Su ◽  
...  

The self-assembly and drug release of the three PEG–PCL copolymers with different topologies but identical molar ratio between PEG to PCL.


2014 ◽  
Vol 998-999 ◽  
pp. 95-98
Author(s):  
Xu Du ◽  
Qin Wang ◽  
Chuan Dong Wang ◽  
Yang Liu

Three biodegradable amphiphilic triblock copolymers: polylactide-poly (ethylene glycol)-polylactide (PLA-PEG-PLA), poly (ε-caprolactone)-poly (ethylene glycol)-poly (ε-caprolactone) (PCL-PEG-PCL) and poly (lactide-glycolide)-poly (ethylene glycol)-poly (lactide-glycolide) (PLGA-PEG-PLGA) were synthesized. Their chemical structures were characterized. In aqueous solution, their self-assembly and degradation were studied by dynamic light scattering (DLS) and transmission electron microscopy (TEM). Spherical micelles were formed in aqueous solution via self-assembly of the amphiphilic triblock copolymers. After degradation, the PLA-PEG-PLA and PCL-PEG-PCL micelles became smaller and the PLGA-PEG-PLGA micelles change to vesicles, which should mainly attribute to their different degradation speed.


2007 ◽  
Vol 21 (28n29) ◽  
pp. 4961-4966
Author(s):  
HUI-RU MA ◽  
JIAN-GUO GUAN ◽  
RUN-ZHANG YUAN

The self-assembly properties and ER effects of the Polyaniline-Poly(ethylene glycol)-Polyaniline (PAn-PEG-PAn) triblock copolymers were studied in this paper. The results indicate that with the increase of solubility parameter of the solvent, PAn-PEG-PAn copolymers form into different morphologies of spheriods, vesicles and rods. PAn-PEG-PAn copolymers with vesicles morphology show the highest polarization strength, while those with rods have the most rapid polarization rate. Among the PAn-PEG-PAn copolymers of different morphologies, the PAn-PEG-PAn copolymer vesicles show the strongest ER effect.


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