A multicomponent reaction on a ‘free’ KCC-1 catalyst at room temperature under solvent free conditions by visible light

RSC Advances ◽  
2016 ◽  
Vol 6 (59) ◽  
pp. 54236-54240 ◽  
Author(s):  
Seyed Mohsen Sadeghzadeh
Keyword(s):  
Visible Light ◽  
Multicomponent Reaction ◽  
Efficient Method ◽  
Room Temperature ◽  
Solvent Free ◽  
Green Protocol ◽  
Mild Conditions ◽  
Solvent Free Conditions

A green and efficient method for the synthesis of various triazolo[1,2-a]indazoletrione under mild conditions is reported, that making it a genuinely green protocol.

An efficient method for the silylation of hydroxyl groups with hexamethyldisilazane (HMDS) catalyzed by aluminum tris(dihydrogen phosphate) under solvent-free and ambient conditions

2008 ◽  
Vol 86 (8) ◽  
pp. 841-845 ◽  
Author(s):  
Hamid Reza Shaterian ◽  
Majid Ghashang ◽  
Nassrin Tajbakhsh Riki ◽  
Manijeh Asadi
Keyword(s):  
Heterogeneous Catalyst ◽  
Efficient Method ◽  
Room Temperature ◽  
Solvent Free ◽  
Dihydrogen Phosphate ◽  
Hydroxyl Groups ◽  
Ambient Conditions ◽  
Solvent Free Conditions ◽  
Free Hydroxyl ◽  
Recyclable Heterogeneous Catalyst

A highly efficient and mild procedure for the trimethylsilylation of a wide variety of alcohols, including primary, benzylic, secondary, hindered secondary, tertiary, phenols, and oximes with hexamethyldisilazane (HMDS), using Al(H2PO4)3 as a recyclable heterogeneous catalyst at room temperature in a few minutes with excellent yields under solvent-free conditions is described.Key words: trimethylsilylation, hexamethyldisilazane, aluminum tris(dihydrogen phosphate) [Al(H2PO4)3], solvent-free, hydroxyl groups.

Efficient Synthesis of Novel Quinolinone Derivatives via Catalyst-free Multicomponent Reaction

2020 ◽  
Vol 17 (5) ◽  
pp. 403-407
Author(s):  
Rui Du ◽  
Liangliang Han ◽  
Zhongqiang Zhou ◽  
Victor Borovkov
Keyword(s):  
Reaction Time ◽  
Multicomponent Reaction ◽  
Room Temperature ◽  
Reaction Rates ◽  
Solvent Free ◽  
Hydroxyl Group ◽  
Efficient Synthesis ◽  
Catalyst Free ◽  
Solvent Free Conditions ◽  
Substituted Benzaldehydes

The synthesis of 3-(aryl(piperidin-1-yl)methyl)-4-hydroxyquinolin-2(1H)-one derivatives via catalyst-free multicomponent reaction is described. The reaction of 4-hydroxyquinolin-2(1H)-one, piperidine, and 4-chlorobenzaldehyde was carried out in different solvents and under solvent-free conditions at room temperature. The best solvent in terms of the yield and reaction time was found to be dichloromethane. Most substituted benzaldehydes reacted with 4-hydroxyquinolin-2(1H)-one and piperidine to afford corresponding products in good-to-excellent yields. Aldehydes with electronwithdrawing groups were more reactive to exhibit higher reaction rates. However, 2-substituted benzaldehydes did not react with 4-hydroxyquinolin-2(1H)-one and piperidine under the reaction condition. Aldehydes bearing a hydroxyl group failed to produce the corresponding products.

A green and clean pathway: one pot, multicomponent, and visible light assisted synthesis of pyrano[2,3-c]pyrazoles under catalyst-free and solvent-free conditions

2017 ◽  
Vol 41 (19) ◽  
pp. 11148-11154 ◽  
Author(s):  
Bhartendu Pati Tripathi ◽  
Anu Mishra ◽  
Pratibha Rai ◽  
Yogesh Kumar Pandey ◽  
Madhulika Srivastava ◽  
...  
Keyword(s):  
Visible Light ◽  
Room Temperature ◽  
Solvent Free ◽  
One Pot ◽  
Catalyst Free ◽  
Solvent Free Conditions

Visible light mediated, an eco-friendlier synthetic protocol for dihydropyrano[2,3-c]pyrazoles via catalyst-free and solvent-free conditions at room temperature.

scholarly journals An Efficient Method for N-Formylation of Amines Using Natural HEU Zeolite at Room Temperature Under Solvent-Free Conditions

2012 ◽  
Vol 33 (7) ◽  
pp. 2251-2254 ◽  
Author(s):  
Siavash Bahari ◽  
Babak Mohammadi-Aghdam ◽  
S. Mohammad Sajadi ◽  
Fereshteh Zeidali
Keyword(s):  
Efficient Method ◽  
Room Temperature ◽  
Solvent Free ◽  
Solvent Free Conditions

ZnO-nanorods Promoted Synthesis of α-amino Nitrile Benzofuran Derivatives using One-pot Multicomponent Reaction of Isocyanides

2020 ◽  
Vol 23 (4) ◽  
pp. 345-355
Author(s):  
Asef H. Najar ◽  
Zinatossadat Hossaini ◽  
Shahrzad Abdolmohammadi ◽  
Daryoush Zareyee
Keyword(s):  
Multicomponent Reaction ◽  
Room Temperature ◽  
Solvent Free ◽  
Primary Amines ◽  
Reusable Catalyst ◽  
Reaction Conditions ◽  
Trimethylsilyl Cyanide ◽  
Solvent Free Conditions ◽  
High Yields ◽  
Amino Nitrile

Aims & Objective: In this work ZnO-nanorod (ZnO-NR) as reusable catalyst promoted Strecker-type reaction of 2,4-dihydroxyacetophenone, isopropenylacetylene, trimethylsilyl cyanide (TMSCN), primary amines and isocyanides at ambient temperature under solvent-free conditions and produced α-amino nitriles benzofuran derivatives in high yields. These synthesized compounds may have antioxidant ability. Materials and Methods: ZnO-NRs in these reactions were prepared according to reported article. 2,4-dihydroxyacetophenone 1 (2 mmol) and isopropenylacetylene 2 (2 mmol) were mixed and stirred for 30 min in the presence of ZnO-NR (10 mol%) under solvent-free conditions at room temperature. After 30 min, primary amine 3 (2 mmol) was added to the mixture gently and the mixture was stirred for 15 min. After this time TMSCN 4 (2 mmol) was added to the mixture and stirred for 15 min. After completion of the reaction, as indicated by TLC, isocyanides 5 was added to mixture in the presence of catalyst. Results: In the first step of this research, the reaction of 2,4-dihydroxyacetophenone 1, isopropenylacetylene 2, methyl amine 3a, trimethylsilyle cyanide 4 and tert-butyl isocyanides 5a was used as a sample reaction to attain the best reaction conditions. The results showed this reaction performed with catalyst and did not have any product without catalyst after 12 h. Conclusion: In conclusion, we investigate multicomponent reaction of 2,4-dihydroxyacetophenone 1, isopropenylacetylene 2, primary amines 3, trimethylsilyl cyanide 4 and isocyanides along with ZnO-NRs as reusable catalyst at room temperature under solvent-free conditions which generates α-amino nitrile benzofuran derivatives in high yields. The advantages of our method are high atom economy, green reaction conditions, higher yield, shorter reaction times, and easy work-up, which are in good agreement with some principles of green chemistry. The compounds 8c exhibit excellent DPPH radical scavenging activity and FRAP compared to synthetic antioxidants BHT and TBHQ.

ChemInform Abstract: Rapid and Efficient Method for Room Temperature Deoximation Reaction under Solvent-Free Conditions.

ChemInform ◽  
2011 ◽  
Vol 42 (46) ◽  
pp. no-no
Author(s):  
Anindita Dewan ◽  
Utpal Bora ◽  
Dilip K. Kakati
Keyword(s):  
Efficient Method ◽  
Room Temperature ◽  
Solvent Free ◽  
Solvent Free Conditions

Nano zirconia catalysed one-pot synthesis of some novel substituted imidazoles under solvent-free conditions

RSC Advances ◽  
2015 ◽  
Vol 5 (36) ◽  
pp. 28163-28170 ◽  
Author(s):  
Shivam Bajpai ◽  
Sundaram Singh ◽  
Vandana Srivastava
Keyword(s):  
Multicomponent Reaction ◽  
Efficient Method ◽  
Ammonium Acetate ◽  
Aromatic Aldehydes ◽  
Solvent Free ◽  
One Pot ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
Solvent Free Conditions ◽  
Isatin Derivatives

A highly efficient method for the synthesis of substituted imidazoles from a multicomponent reaction of isatin derivatives with ammonium acetate and aromatic aldehydes under solvent-free conditions has been established.

scholarly journals Chemoselective Preparation of 1,1-Diacetates from Aldehydes, Mediated by a Keggin Heteropolyacid Under Solvent Free Conditions at Room Temperature

2007 ◽  
Vol 4 (1) ◽  
pp. 83-89 ◽  
Author(s):  
G. Romanelli ◽  
P. Dimitroff ◽  
P. Vázquez ◽  
J. C. Autino
Keyword(s):  
Acetic Anhydride ◽  
Efficient Method ◽  
Room Temperature ◽  
Catalytic Amount ◽  
Solvent Free ◽  
Solvent Free Conditions

A simple, general and efficient method has been developed for the conversion of aldehydes to 1,1-diacetates using acetic anhydride, a catalytic amount of non commercial Keggin heteropolyacid (H6PalMo11O40) (1% mol) in solvent free conditions at room temperature. Aromatic and aliphatic, simple and conjugated aldehydes were protected with excellent yields.

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