ChemInform Abstract: A Multicomponent Reaction on a ′Free′ KCC-1 Catalyst at Room Temperature under Solvent Free Conditions by Visible Light.

ChemInform ◽  
2016 ◽  
Vol 47 (42) ◽  
Author(s):  
Seyed Mohsen Sadeghzadeh
Keyword(s):  
Visible Light ◽  
Multicomponent Reaction ◽  
Room Temperature ◽  
Solvent Free ◽  
Solvent Free Conditions

A multicomponent reaction on a ‘free’ KCC-1 catalyst at room temperature under solvent free conditions by visible light

RSC Advances ◽  
2016 ◽  
Vol 6 (59) ◽  
pp. 54236-54240 ◽  
Author(s):  
Seyed Mohsen Sadeghzadeh
Keyword(s):  
Visible Light ◽  
Multicomponent Reaction ◽  
Efficient Method ◽  
Room Temperature ◽  
Solvent Free ◽  
Green Protocol ◽  
Mild Conditions ◽  
Solvent Free Conditions

A green and efficient method for the synthesis of various triazolo[1,2-a]indazoletrione under mild conditions is reported, that making it a genuinely green protocol.

Efficient Synthesis of Novel Quinolinone Derivatives via Catalyst-free Multicomponent Reaction

2020 ◽  
Vol 17 (5) ◽  
pp. 403-407
Author(s):  
Rui Du ◽  
Liangliang Han ◽  
Zhongqiang Zhou ◽  
Victor Borovkov
Keyword(s):  
Reaction Time ◽  
Multicomponent Reaction ◽  
Room Temperature ◽  
Reaction Rates ◽  
Solvent Free ◽  
Hydroxyl Group ◽  
Efficient Synthesis ◽  
Catalyst Free ◽  
Solvent Free Conditions ◽  
Substituted Benzaldehydes

The synthesis of 3-(aryl(piperidin-1-yl)methyl)-4-hydroxyquinolin-2(1H)-one derivatives via catalyst-free multicomponent reaction is described. The reaction of 4-hydroxyquinolin-2(1H)-one, piperidine, and 4-chlorobenzaldehyde was carried out in different solvents and under solvent-free conditions at room temperature. The best solvent in terms of the yield and reaction time was found to be dichloromethane. Most substituted benzaldehydes reacted with 4-hydroxyquinolin-2(1H)-one and piperidine to afford corresponding products in good-to-excellent yields. Aldehydes with electronwithdrawing groups were more reactive to exhibit higher reaction rates. However, 2-substituted benzaldehydes did not react with 4-hydroxyquinolin-2(1H)-one and piperidine under the reaction condition. Aldehydes bearing a hydroxyl group failed to produce the corresponding products.

A green and clean pathway: one pot, multicomponent, and visible light assisted synthesis of pyrano[2,3-c]pyrazoles under catalyst-free and solvent-free conditions

2017 ◽  
Vol 41 (19) ◽  
pp. 11148-11154 ◽  
Author(s):  
Bhartendu Pati Tripathi ◽  
Anu Mishra ◽  
Pratibha Rai ◽  
Yogesh Kumar Pandey ◽  
Madhulika Srivastava ◽  
...  
Keyword(s):  
Visible Light ◽  
Room Temperature ◽  
Solvent Free ◽  
One Pot ◽  
Catalyst Free ◽  
Solvent Free Conditions

Visible light mediated, an eco-friendlier synthetic protocol for dihydropyrano[2,3-c]pyrazoles via catalyst-free and solvent-free conditions at room temperature.

ZnO-nanorods Promoted Synthesis of α-amino Nitrile Benzofuran Derivatives using One-pot Multicomponent Reaction of Isocyanides

2020 ◽  
Vol 23 (4) ◽  
pp. 345-355
Author(s):  
Asef H. Najar ◽  
Zinatossadat Hossaini ◽  
Shahrzad Abdolmohammadi ◽  
Daryoush Zareyee
Keyword(s):  
Multicomponent Reaction ◽  
Room Temperature ◽  
Solvent Free ◽  
Primary Amines ◽  
Reusable Catalyst ◽  
Reaction Conditions ◽  
Trimethylsilyl Cyanide ◽  
Solvent Free Conditions ◽  
High Yields ◽  
Amino Nitrile

Aims & Objective: In this work ZnO-nanorod (ZnO-NR) as reusable catalyst promoted Strecker-type reaction of 2,4-dihydroxyacetophenone, isopropenylacetylene, trimethylsilyl cyanide (TMSCN), primary amines and isocyanides at ambient temperature under solvent-free conditions and produced α-amino nitriles benzofuran derivatives in high yields. These synthesized compounds may have antioxidant ability. Materials and Methods: ZnO-NRs in these reactions were prepared according to reported article. 2,4-dihydroxyacetophenone 1 (2 mmol) and isopropenylacetylene 2 (2 mmol) were mixed and stirred for 30 min in the presence of ZnO-NR (10 mol%) under solvent-free conditions at room temperature. After 30 min, primary amine 3 (2 mmol) was added to the mixture gently and the mixture was stirred for 15 min. After this time TMSCN 4 (2 mmol) was added to the mixture and stirred for 15 min. After completion of the reaction, as indicated by TLC, isocyanides 5 was added to mixture in the presence of catalyst. Results: In the first step of this research, the reaction of 2,4-dihydroxyacetophenone 1, isopropenylacetylene 2, methyl amine 3a, trimethylsilyle cyanide 4 and tert-butyl isocyanides 5a was used as a sample reaction to attain the best reaction conditions. The results showed this reaction performed with catalyst and did not have any product without catalyst after 12 h. Conclusion: In conclusion, we investigate multicomponent reaction of 2,4-dihydroxyacetophenone 1, isopropenylacetylene 2, primary amines 3, trimethylsilyl cyanide 4 and isocyanides along with ZnO-NRs as reusable catalyst at room temperature under solvent-free conditions which generates α-amino nitrile benzofuran derivatives in high yields. The advantages of our method are high atom economy, green reaction conditions, higher yield, shorter reaction times, and easy work-up, which are in good agreement with some principles of green chemistry. The compounds 8c exhibit excellent DPPH radical scavenging activity and FRAP compared to synthetic antioxidants BHT and TBHQ.

Preparation and Characterization of a Novel Room Temperature Dicationic Ionic Liquid and its Application in the Synthesis of Xanthenediones Under Solvent-Free Conditions

2018 ◽  
Vol 21 (8) ◽  
pp. 602-608 ◽  
Author(s):  
Zainab Ehsani-Nasab ◽  
Ali Ezabadi
Keyword(s):  
Ionic Liquid ◽  
Room Temperature ◽  
Reaction Times ◽  
Significant Loss ◽  
Solvent Free ◽  
Acidity Function ◽  
Efficient Catalyst ◽  
Solvent Free Conditions ◽  
Hammett Acidity Function ◽  
Dicationic Ionic Liquid

Aim and Objective: In the present work, 1, 1’-sulfinyldiethylammonium bis (hydrogen sulfate) as a novel room temperature dicationic ionic liquid was synthesized and used as a catalyst for xanthenediones synthesis. Material and Method: The dicationic ionic liquid has been synthesized using ethylamine and thionyl chloride as precursors. Then, by the reaction of [(EtNH2)2SO]Cl2 with H2SO4, [(EtNH2)2SO][HSO4]2 was prepared and after that, it was characterized by FT-IR, 1H NMR, 13C NMR as well as Hammett acidity function. This dicationic ionic liquid was used as a catalyst for the synthesis of xanthenediones via condensation of structurally diverse aldehydes and dimedone under solvent-free conditions. The progress of the reaction was monitored by thin layer chromatography (ethyl acetate/n-hexane = 3/7). Results: An efficient solvent-free method for the synthesis of xanthenediones has been developed in the presence of [(EtNH2)2SO][HSO4]2 as a powerful catalyst with high to excellent yields, and short reaction times. Additionally, recycling studies have demonstrated that the dicationic ionic liquid can be readily recovered and reused at least four times without significant loss of its catalytic activity. Conclusion: This new dicationic ionic liquid can act as a highly efficient catalyst for xanthenediones synthesis under solvent-free conditions.

Efficient Synthesis of Tetrahydrobenzo[b]pyrans under Solvent‐Free Conditions at Room Temperature

2006 ◽  
Vol 36 (16) ◽  
pp. 2363-2369 ◽  
Author(s):  
Liangce Rong ◽  
Xiaoyue Li ◽  
Haiying Wang ◽  
Daqing Shi ◽  
Shujiang Tu ◽  
...  
Keyword(s):  
Room Temperature ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
Solvent Free Conditions

Synthesis of 1,1-diacetates from Aromatic Aldehydes using Cerium(IV) Sulfate Tetrahydrate as Catalyst under Solvent-free Conditions

2005 ◽  
Vol 2005 (3) ◽  
pp. 171-172 ◽  
Author(s):  
Min Zhang ◽  
Yi-Qun Li
Keyword(s):  
Room Temperature ◽  
Aromatic Aldehydes ◽  
Solvent Free ◽  
Excellent Yield ◽  
Solvent Free Conditions

Aromatic aldehydes can be converted into the corresponding 1,1-diacetates rapidly in the presence of catalytic amounts of Ce(SO4)2·4H2O at room temperature in excellent yield under solvent-free conditions. The catalyst can easily be recovered and reused at least 4 times.

Solid lithium perchlorate as a powerful catalyst for the synthesis of β-aminoalcohols under solvent-free conditions

2005 ◽  
Vol 83 (5) ◽  
pp. 505-507 ◽  
Author(s):  
Najmodin Azizi ◽  
Mohammad R Saidi
Keyword(s):  
Ring Opening ◽  
Room Temperature ◽  
Lithium Perchlorate ◽  
Solvent Free ◽  
Solvent Free Conditions ◽  
Reaction Proceeds ◽  
Ring Opening Of Epoxides ◽  
Neutral Conditions ◽  
Hindered Amines ◽  
Short Times

Lithium perchlorate catalyzed the ring opening of epoxides with amines to provide the corresponding β-aminoalcohols in excellent yields with high regioselectivity. The reaction proceeds rapidly under mild and neutral conditions and worked well with primary, secondary, aliphatic, aromatic, and hindered amines in short times at room temperature, in the absence of solvent.Key words: epoxide, lithium perchlorate, β-aminoalcohols, solvent-free.

Sign in / Sign up

Export Citation Format

Share Document