Large-pore mesoporous Ca–Si-based bioceramics with high in vitro bioactivity and protein adsorption capability for bone tissue regeneration

2016 ◽  
Vol 4 (22) ◽  
pp. 3916-3924 ◽  
Author(s):  
Xingdi Zhang ◽  
Deliang Zeng ◽  
Nan Li ◽  
Xinquan Jiang ◽  
Changsheng Liu ◽  
...  
Keyword(s):  
Protein Adsorption ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration ◽  
In Vitro Bioactivity ◽  
Large Pore ◽  
New Type ◽  
Adsorption Capability

A new type of large pore mesoporous Ca–Si-based bioceramics demonstrates high in vitro bioactivity and protein adsorption capability.

Enhancing in vitro bioactivity and in vivo osteogenesis of organic–inorganic nanofibrous biocomposites with novel bioceramics

2014 ◽  
Vol 2 (37) ◽  
pp. 6293-6305 ◽  
Author(s):  
Tao Liu ◽  
Xinbo Ding ◽  
Dongzhi Lai ◽  
Yongwei Chen ◽  
Ridong Zhang ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Biological Properties ◽  
Bone Tissue Regeneration ◽  
In Vitro Bioactivity ◽  
Physicochemical And Biological Properties

MGHA-introduced, an electrospun SF-based composite can exhibit improved physicochemical and biological properties to stimulate bone tissue regeneration and repair.

Thermal and in vitro evaluation of a composite material pHEMA/Chitosan/Hydroxyapatite

2015 ◽  
Vol 1767 ◽  
pp. 133-138
Author(s):  
Areli.M. Salgado-Delgado ◽  
Zully Vargas-Galarza ◽  
René Salgado-Delgado ◽  
Efraín Rubio-Rosas ◽  
Edgar García-Hernández ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Body Fluid ◽  
Bone Tissue Regeneration ◽  
Gravimetric Analysis ◽  
Hydroxyethyl Methacrylate ◽  
Thermal Gravimetric ◽  
In Vitro Bioactivity ◽  
Bioactive Materials

ABSTRACTBioactive materials based on polymer/hydroxyapatite are currently being extensively investigated as materials for promotion of bone tissue regeneration and reconstruction [1]. In this work, a material interpenetrating based on poly 2-hydroxyethyl methacrylate (pHEMA), Chitosan and hydroxyapatite (HA) was prepared following the methodology of the foaming gas Damla Çetin [2], generating an interpenetrated network with the chitosan filled with hydroxyapatite. The materials were evaluated by thermal gravimetric analysis (TGA) and in vitro bioactivity [3] (SBF) and characterized by using scanning electron microscopy (SEM). The TGA studies suggested that there was not existence of possible interactions between polymers and HA but there is a thermal stability increase in the HA content. Meanwhile, SBF and its characterization by SEM, was found that the materials are bioactives as indicated by the formation of a bone-like apatite layer after immersion in simulated body fluid, indicating the potential of this material for use in bone tissue engineering.

Fabrication, characterization, and in vitro biological activities of melt-electrospun PLA micro/nanofibers for bone tissue regeneration

2013 ◽  
Vol 1 (30) ◽  
pp. 3670 ◽  
Author(s):  
Hyeongjin Lee ◽  
Seunghyun Ahn ◽  
Hyongwoo Choi ◽  
Daehwan Cho ◽  
GeunHyung Kim
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Biological Activities ◽  
Bone Tissue Regeneration

scholarly journals Fabrication of High-Strength and Porous Hybrid Scaffolds Based on Nano-Hydroxyapatite and Human-Like Collagen for Bone Tissue Regeneration

Polymers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 61 ◽  
Author(s):  
Yannan Liu ◽  
Juan Gu ◽  
Daidi Fan
Keyword(s):  
Mechanical Properties ◽  
Enzymatic Hydrolysis ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Bone Repair ◽  
Three Dimensional ◽  
High Strength ◽  
Biological Properties ◽  
Bone Tissue Regeneration

A novel, three-dimensional, porous, human-like collagen (HLC)/nano-hydroxyapatite (n-HA) scaffold cross-linked by 1,2,7,8-diepoxyoctane (DEO) was successfully fabricated, which showed excellent mechanical and superior biological properties for bone tissue regeneration in this study. The physicochemical characterizations of different n-HA/HLC/DEO (nHD) scaffolds were investigated by determining the morphology, compression stress, elastic modulus, Young’s modulus and enzymatic hydrolysis behavior in vitro. The results demonstrated that nHD-2 and nHD-3 scaffolds showed superior mechanical properties and resistance to enzymatic hydrolysis compared to nHD-1 scaffolds. The cell viability, live cell staining and cell adhesion analysis results demonstrated that nHD-2 scaffolds exhibited low cytotoxicity and excellent cytocompatibility compared with nHD-1 and nHD-3 scaffolds. Furthermore, subcutaneous injections of nHD-2 scaffolds in rabbits produced superior anti-biodegradation effects and histocompatibility compared with injections of nHD-1 and nHD-3 scaffolds after 1, 2 and 4 weeks. In addition, the repair of bone defects in rabbits demonstrated that nHD-2 scaffolds presented an improved ability for guided bone regeneration and reconstruction compared to commercially available bone scaffold composite hydroxyapatite/collagen (HC). Collectively, the results show that nHD-2 scaffolds show promise for application in bone tissue engineering due to their excellent mechanical properties, anti-biodegradation, anti-biodegradation, biocompatibility and bone repair effects.

Scaffolds containing chitosan, gelatin and graphene oxide for bone tissue regeneration in vitro and in vivo

2017 ◽  
Vol 104 ◽  
pp. 1975-1985 ◽  
Author(s):  
S. Saravanan ◽  
Anjali Chawla ◽  
M. Vairamani ◽  
T.P. Sastry ◽  
K.S. Subramanian ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Bone Tissue Regeneration ◽  
Regeneration In Vitro
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