A novel dual target simultaneous chemiluminescence signal amplification strategy for enhancing sensitivity of multiple biomolecule detection

2017 ◽  
Vol 9 (48) ◽  
pp. 6785-6790 ◽  
Author(s):  
Jian Li ◽  
Jingjin Zhao ◽  
Shuting Li ◽  
Liangliang Zhang ◽  
Chuanqing Lan ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Simultaneous Detection ◽  
Microchip Electrophoresis ◽  
Biomolecule Detection ◽  
G Quadruplex ◽  
Electrophoresis Method ◽  
Amplification Strategy ◽  
Nicking Enzyme ◽  
Dual Target

A G-quadruplex DNAzyme and nicking enzyme assisted multiplex chemiluminescence signal amplification based microchip electrophoresis method was developed for simultaneous detection of two trace biomolecules.

A label-free and enzyme-free signal amplification strategy for a sensitive RNase H activity assay

Nanoscale ◽  
2017 ◽  
Vol 9 (42) ◽  
pp. 16149-16153 ◽  
Author(s):  
Chang Yeol Lee ◽  
Hyowon Jang ◽  
Ki Soo Park ◽  
Hyun Gyu Park
Keyword(s):  
Signal Amplification ◽  
Rnase H ◽  
Label Free ◽  
Activity Assay ◽  
G Quadruplex ◽  
Catalytic Hairpin Assembly ◽  
Amplification Strategy

A target-triggered catalytic hairpin assembly with a G-quadruplex specific fluorescent binder, NMM, is employed to develop a novel and sensitive RNase H activity assay.

K-junction structure mediated exponential signal amplification strategy for microRNA detection in electrochemiluminescence biosensor

The Analyst ◽  
2017 ◽  
Vol 142 (12) ◽  
pp. 2185-2190 ◽  
Author(s):  
Xue Li ◽  
Anyi Chen ◽  
Yaqin Chai ◽  
Ruo Yuan
Keyword(s):  
Signal Amplification ◽  
The Novel ◽  
Microrna Detection ◽  
G Quadruplex ◽  
Simple Protocol ◽  
Amplification Strategy ◽  
Junction Structure

Based on the novel designed K-junction structure, an economic and efficient exponential signal amplification strategy with simple protocol combining hemin/G-quadruplex, a mimetic peroxidase, as a catalyzer was proposed and utilized in an electrochemiluminescence biosensor for sensitive microRNA detection.

scholarly journals A microchip electrophoresis-based fluorescence signal amplification strategy for highly sensitive detection of biomolecules

2017 ◽  
Vol 53 (2) ◽  
pp. 455-458 ◽  
Author(s):  
Yingfeng Qin ◽  
Liangliang Zhang ◽  
Shuting Li ◽  
Jingjin Zhao ◽  
Yong Huang ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Microchip Electrophoresis ◽  
Sensitive Detection ◽  
Fluorescence Signal ◽  
Highly Sensitive ◽  
Fluorescence Signal Amplification ◽  
Detection Of Biomolecules ◽  
Highly Sensitive Detection ◽  
Amplification Strategy

A microchip electrophoresis-based fluorescence signal amplification strategy was developed for highly sensitive detection of biomolecules.

A novel multiplex signal amplification strategy based on microchip electrophoresis platform for the improved separation and detection of microRNAs

Talanta ◽  
2018 ◽  
Vol 189 ◽  
pp. 437-441 ◽  
Author(s):  
Kaiji Wei ◽  
Jingjin Zhao ◽  
Yingfeng Qin ◽  
Shuting Li ◽  
Yong Huang ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Microchip Electrophoresis ◽  
Amplification Strategy

A novel intracellular signal amplification strategy for the quantification of ATP in single cells by microchip electrophoresis with laser-induced fluorescence detection

2020 ◽  
Vol 56 (48) ◽  
pp. 6579-6582 ◽  
Author(s):  
Shengyu Chen ◽  
Jingjin Zhao ◽  
Xing Yang ◽  
Shulin Zhao ◽  
Yi-Ming Liu
Keyword(s):  
Fluorescence Detection ◽  
Signal Amplification ◽  
Single Cells ◽  
Microchip Electrophoresis ◽  
Laser Induced Fluorescence ◽  
Laser Induced Fluorescence Detection ◽  
Intracellular Signal ◽  
Amplification Strategy

An intracellular signal amplification strategy was developed for the quantification of ATP in single cells by microchip electrophoresis laser-induced fluorescence detection.

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