A two-photon fluorescent probe for ratiometric imaging of endogenous hypochlorous acid in live cells and tissues

2017 ◽  
Vol 53 (78) ◽  
pp. 10800-10803 ◽  
Author(s):  
Yong Woong Jun ◽  
Sourav Sarkar ◽  
Subhankar Singha ◽  
Ye Jin Reo ◽  
Hye Rim Kim ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Fluorescent Probe ◽  
Hypochlorous Acid ◽  
Reactive Oxygen ◽  
Live Cells ◽  
Oxygen Species ◽  
Two Photon ◽  
Ratiometric Imaging ◽  
In Cells

A fluorescent probe enables two-photon ratiometric imaging of endogenous hypochlorous acid, a reactive oxygen species, in cells and tissues.

scholarly journals Development of an ultrafast fluorescent probe for specific recognition of hypochlorous acid and its application in live cells

RSC Advances ◽  
2021 ◽  
Vol 11 (40) ◽  
pp. 24669-24672
Author(s):  
Zhencai Xu ◽  
Xiaofeng Wang ◽  
Tingting Duan ◽  
Rong He ◽  
Fangwu Wang ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Fluorescent Probe ◽  
Hypochlorous Acid ◽  
Reactive Oxygen ◽  
Inflammatory Cells ◽  
Live Cells ◽  
Oxygen Species ◽  
Specific Recognition

Hypochlorous acid (HOCl), a highly potent oxidant of reactive oxygen species, plays critical roles in many physiological and pathological processes. In this work, we designed a simple coumarin-based fluorescent probe, Cou–HOCl, for detecting HOCl in inflammatory cells.

A two-photon fluorescent probe for ratiometric visualization of hypochlorous acid in live cells and animals based on a selenide oxidation/elimination tandem reaction

2018 ◽  
Vol 54 (84) ◽  
pp. 11965-11968 ◽  
Author(s):  
Xilei Xie ◽  
Tianhong Wu ◽  
Xu Wang ◽  
Yong Li ◽  
Kaiye Wang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Hypochlorous Acid ◽  
Live Cells ◽  
Tandem Reaction ◽  
Two Photon ◽  
Ratiometric Imaging ◽  
Sensing Performance

A fluorescent probe with superior sensing performance enables two-photon ratiometric imaging of biogenic hypochlorous acid in live cells and animals.

Reversible two-photon fluorescent probe for imaging of hypochlorous acid in live cells and in vivo

2015 ◽  
Vol 51 (50) ◽  
pp. 10150-10153 ◽  
Author(s):  
Wei Zhang ◽  
Wei Liu ◽  
Ping Li ◽  
Junqing kang ◽  
Jiaoyang Wang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Hypochlorous Acid ◽  
Live Cells ◽  
Two Photon ◽  
In Cells

A novel reversible two-photon fluorescent probe was developed, which was well suited for the selective and instantaneous monitoring of HOCl levels, and it was successfully applied for the imaging of HOCl levels in cells andin vivo.

Development of an endoplasmic reticulum-targeting fluorescent probe for the two-photon imaging of hypochlorous acid (HClO) in living cells

2019 ◽  
Vol 11 (35) ◽  
pp. 4450-4455 ◽  
Author(s):  
Wenhui Song ◽  
Baoli Dong ◽  
Yaru Lu ◽  
Xiuqi Kong ◽  
Abdul Hadi Mehmood ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Endoplasmic Reticulum ◽  
Cell Death ◽  
Fluorescent Probe ◽  
Hypochlorous Acid ◽  
Living Cells ◽  
Oxygen Species ◽  
Cell Dysfunction ◽  
Two Photon ◽  
Endoplasmic Reticulum Targeting

As an important reactive oxygen species, hypochlorous acid (HClO) could irreversibly destroy Ca2+-ATPase to inhibit Ca2+ transport in the endoplasmic reticulum (ER), which may eventually lead to cell dysfunction and cell death.

A novel colorimetric and far-red emission ratiometric fluorescent probe for the highly selective and ultrafast detection of hypochlorite in water and its application in bioimaging

The Analyst ◽  
2020 ◽  
Vol 145 (3) ◽  
pp. 939-945 ◽  
Author(s):  
Yuanyuan Zhang ◽  
Yufan Ma ◽  
Zhuo Wang ◽  
Xueyan Zhang ◽  
Xin Chen ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Fluorescent Probe ◽  
Hypochlorous Acid ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Red Emission ◽  
Physiological Processes ◽  
Ultrafast Detection ◽  
Ratiometric Fluorescent Probe

Hypochlorous acid (HOCl)/hypochlorite (OCl−), an important reactive oxygen species, plays a number of important roles in various physiological processes.

A versatile two-photon fluorescent probe for ratiometric imaging E. coli β-galactosidase in live cells and in vivo

2016 ◽  
Vol 52 (53) ◽  
pp. 8283-8286 ◽  
Author(s):  
Xue-Xiang Zhang ◽  
Hao Wu ◽  
Peng Li ◽  
Zong-Jin Qu ◽  
Ming-Qian Tan ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Stokes Shift ◽  
Live Cells ◽  
E Coli ◽  
Large Stokes Shift ◽  
Two Photon ◽  
Ratiometric Imaging ◽  
In Cells

A ratiometric two-photon probe with a large Stokes shift has been developed to practically achieve sensing β-galactosidase in cells and in mice.

Construction of A Near-infrared Fluorescent Probe for Ratiometric Imaging of Peroxynitrite during tumor progression

The Analyst ◽  
2021 ◽  
Author(s):  
Zan Li ◽  
Jiao Lu ◽  
Qing Pang ◽  
Jinmao You
Keyword(s):  
Reactive Oxygen Species ◽  
Tumor Progression ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Malignant Tumors ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Ratiometric Imaging ◽  
Human Death

Malignant tumors are one of the main causes for human death, which are tightly associated with overexpression of reactive oxygen species (ROS) in pathological processes. Therefore, in vivo monitoring of...

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