Switch-on fluorescent/FRET probes to study human histidine triad nucleotide binding protein 1 (hHint1), a novel target for opioid tolerance and neuropathic pain

2017 ◽  
Vol 15 (48) ◽  
pp. 10230-10237 ◽  
Author(s):  
Rachit Shah ◽  
Andrew Zhou ◽  
Carston R. Wagner
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neuropathic Pain ◽  
Binding Protein ◽  
Nucleotide Binding ◽  
Opioid Tolerance ◽  
Synaptic Protein ◽  
Central Nervous System Disorders ◽  
Novel Target ◽  
Nucleotide Binding Protein

Histidine Triad Nucleotide Binding Protein 1 (Hint1) has emerged to be an important post-synaptic protein associated with a variety of central nervous system disorders such as pain, addiction, and schizophrenia.

Central nervous system disorders and damage: Implications for stress, anxiety, and depression

2007 ◽  
Author(s):  
P. S. Seibert ◽  
P. D. Parker ◽  
C. M. Patterson ◽  
N. Whitener ◽  
J. O'Donnell ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Anxiety And Depression ◽  
Central Nervous System Disorders
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