A novel amplified double-quenching aptasensor for cocaine detection based on split aptamer and silica nanoparticles

2018 ◽  
Vol 10 (26) ◽  
pp. 3232-3236 ◽  
Author(s):  
Khalil Abnous ◽  
Noor Mohammad Danesh ◽  
Mohammad Ramezani ◽  
Seyed Mohammad Taghdisi ◽  
Ahmad Sarreshtehdar Emrani
Keyword(s):  
Silica Nanoparticles ◽  
Illicit Drug ◽  
Double Quenching ◽  
Cocaine Detection ◽  
Amplification Strategy ◽  
Fluorescent Aptasensor

Herein, a sensitive and rapid fluorescent aptasensor was developed for the detection of cocaine as an illicit drug, based on an amplification strategy involving the use of silica nanoparticles coated with streptavidin (SNPs), double quenching of FAM fluorophore and cocaine split aptamer.

Detection of kanamycin by using an aptamer-based biosensor using silica nanoparticles

2015 ◽  
Vol 7 (20) ◽  
pp. 8611-8616 ◽  
Author(s):  
Ladan Saadat Khabbaz ◽  
Mohammad Hassanzadeh-Khayyat ◽  
Pouya Zaree ◽  
Mohammad Ramezani ◽  
Khalil Abnous ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Sensitive Detection ◽  
Fluorescent Aptasensor

A fluorescent aptasensor system has been designed for the sensitive detection of kanamycin based on silica nanoparticles (SNPs) coated with streptavidin.

A novel fluorescent aptasensor for selective and sensitive detection of digoxin based on silica nanoparticles

2015 ◽  
Vol 7 (9) ◽  
pp. 3814-3818 ◽  
Author(s):  
Ahmad Sarreshtehdar Emrani ◽  
Seyed Mohammad Taghdisi ◽  
Noor Mohammad Danesh ◽  
Seyed Hamid Jalalian ◽  
Mohammad Ramezani ◽  
...  
Keyword(s):  
Heart Failure ◽  
Silica Nanoparticles ◽  
Sensitive Detection ◽  
Fluorescent Aptasensor

Digoxin is a useful drug in the treatment of heart failure.

A novel fluorescent aptasensor based on gold and silica nanoparticles for the ultrasensitive detection of ochratoxin A

Nanoscale ◽  
2016 ◽  
Vol 8 (6) ◽  
pp. 3439-3446 ◽  
Author(s):  
Seyed Mohammad Taghdisi ◽  
Noor Mohammad Danesh ◽  
Hamed Reza Beheshti ◽  
Mohammad Ramezani ◽  
Khalil Abnous
Keyword(s):  
Silica Nanoparticles ◽  
Ochratoxin A ◽  
Ultrasensitive Detection ◽  
Fluorescent Aptasensor

A novel, label-free fluorescent aptasensor for cocaine detection based on a G-quadruplex and ruthenium polypyridyl complex molecular light switch

2016 ◽  
Vol 8 (18) ◽  
pp. 3740-3746 ◽  
Author(s):  
Songbai Zhang ◽  
Linping Wang ◽  
Meiling Liu ◽  
Yanqing Qiu ◽  
Mengna Wang ◽  
...  
Keyword(s):  
High Selectivity ◽  
Label Free ◽  
Ruthenium Polypyridyl ◽  
Polypyridyl Complex ◽  
G Quadruplex ◽  
Molecular Light Switch ◽  
Cocaine Detection ◽  
Fluorescent Aptasensor

A [Ru(bpy)2(bqdppz)]2+ ligand with high selectivity towards G-quadruplex was synthesized and introduced to serve as a prominent molecular light switch via specifically recognizing the cocaine aptamer-involved G-quadruplex.

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