An estrogen receptor targeted ruthenium complex as a two-photon photodynamic therapy agent for breast cancer cells

2018 ◽  
Vol 54 (51) ◽  
pp. 7038-7041 ◽  
Author(s):  
Xueze Zhao ◽  
Mingle Li ◽  
Wen Sun ◽  
Jiangli Fan ◽  
Jianjun Du ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Ruthenium Complex ◽  
Two Photon ◽  
Polypyridyl Complex

In this study, we reported a tamoxifen modified Ru(ii) polypyridyl complex (Ru-tmxf) as an estrogen receptor (ER) targeted photosensitizer.

scholarly journals Biocompatible conjugated fluorenylporphyrins for two-photon photodynamic therapy and fluorescence imaging

2019 ◽  
Vol 55 (81) ◽  
pp. 12231-12234 ◽  
Author(s):  
Limiao Shi ◽  
Christophe Nguyen ◽  
Morgane Daurat ◽  
Abdelhamid Chiheb Dhieb ◽  
Wajda Smirani ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Fluorescence Imaging ◽  
Breast Cancer Cells ◽  
Two Photon ◽  
Theranostic Applications

Three new biocompatible porphyrin-based oxygen photosensitisers were tested in vitro on breast cancer cells via 2P-PDT: one of them, 66 times more active than H2TPP, gave quite promising results for theranostic applications.

Fluorescent periodic mesoporous organosilica nanoparticles dual-functionalized via click chemistry for two-photon photodynamic therapy in cells

2016 ◽  
Vol 4 (33) ◽  
pp. 5567-5574 ◽  
Author(s):  
Jonas G. Croissant ◽  
Sébastien Picard ◽  
Dina Aggad ◽  
Maxime Klausen ◽  
Chiara Mauriello Jimenez ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Photodynamic Therapy ◽  
Click Chemistry ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Periodic Mesoporous Organosilica ◽  
Two Photon ◽  
Mesoporous Organosilica ◽  
Photon Imaging ◽  
In Cells

The synthesis of ethenylene-based periodic mesoporous organosilica nanoparticles for two-photon imaging and photodynamic therapy of breast cancer cells is described.

Ruthenium(ii) complexes as bioorthogonal two-photon photosensitizers for tumour-specific photodynamic therapy against triple-negative breast cancer cells

2021 ◽  
Author(s):  
Mingwei Lin ◽  
Shanshan Zou ◽  
Xinxing Liao ◽  
Yu Chen ◽  
Diqing Luo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Triple Negative Breast Cancer ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
Two Photon

We developed the first Ru(ii) complex-based bioorthogonal two-photon photosensitizers. Through bioorthogonal labelling, they realize effective tumour-specific photodynamic therapy against triple-negative breast cancer cells.

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