Usefulness of ionic liquids as mobile phase modifiers in HPLC-CV-AFS for mercury speciation analysis in food

2018 ◽  
Vol 33 (5) ◽  
pp. 822-834 ◽  
Author(s):  
Alexander Castro Grijalba ◽  
Pamela Y. Quintas ◽  
Emiliano F. Fiorentini ◽  
Rodolfo G. Wuilloud
Keyword(s):  
Ionic Liquids ◽  
Mobile Phase ◽  
Speciation Analysis ◽  
Food Samples ◽  
Mercury Speciation ◽  
Mobile Phase Modifiers

Efficient Hg speciation analysis in different food samples was achieved with ionic liquids as mobile phase modifiers in HPLC-CV-AFS.

scholarly journals Analysis of antisense oligonucleotides with the use of ionic liquids as mobile phase modifiers

RSC Advances ◽  
2019 ◽  
Vol 9 (67) ◽  
pp. 39100-39110 ◽  
Author(s):  
Anna Kaczmarkiewicz ◽  
Judyta Zielak ◽  
Łukasz Nuckowski ◽  
Sylwia Studzińska
Keyword(s):  
Ionic Liquids ◽  
Antisense Oligonucleotides ◽  
Mobile Phase ◽  
Mobile Phase Modifiers ◽  
The Impact

The main goal of this study was the investigation of the impact of several ionic liquids, commonly used as free silanol suppressors, on the retention and separation of phosphorothioate oligonucleotides.

Ionic Liquids as Novel Solvent Additives to Separate Peptides

2006 ◽  
Vol 61 (11-12) ◽  
pp. 827-832 ◽  
Author(s):  
Tomasz Bączek ◽  
Barbara Sparzak
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Thin Layer ◽  
Mobile Phase ◽  
Analytical Approach ◽  
Quantitative Structure ◽  
Methyl Sulfate ◽  
Liquid Content ◽  
Structure Retention ◽  
Layer Chromatography

Abstract A novel analytical approach involving the addition of an ionic liquid into the mobile phase of the thin-layer chromatography (TLC) system during the optimization of chromatographic separation of peptides was demonstrated. Different behavior of peptides in the TLC sytem was observed after the addition of 1,3-dimethylimidazolium methyl sulfate to the eluent in comparison to the system without the ionic liquid. The objective of the work was to study the effect of the addition of different contents of ionic liquid to the mobile phase comprising mostly water and to observe the behavior of peptides’ retention. The potential usefulness of environmentally friendly ionic liquids for the optimization of separation of peptides was demonstrated. An increase of Rf values was observed with increasing the ionic liquid content in the mobile phase. The benefits of the used approach were related to the separation achieved. Finally, quantitative structure-retention relationships (QSRR) were used for the studies on the predictions of peptides’ retention in the TLC systems with the addition of ionic liquid in terms of the predictions performed recently in HPLC systems.

scholarly journals Method validation for simultaneous quantification of some Human Milk Oligosaccharides (HMOs) in dietary supplements by liquid chromatography tandem mass spectrometry (LC-MS/MS)

2021 ◽  
Vol 4 (1) ◽  
pp. 24-26
Author(s):  
Hong Ngoc Nguyen Thi ◽  
Thanh Hoa Mac Thi ◽  
Son Tran Hung ◽  
Dung Ngo Manh ◽  
Khanh Cao Cong ◽  
...  
Keyword(s):  
Human Milk ◽  
Dietary Supplements ◽  
Mobile Phase ◽  
Food Samples ◽  
Phase System ◽  
Time Analysis ◽  
Simultaneous Quantification ◽  
Chromatography Tandem Mass Spectrometry ◽  
Validation Parameters ◽  
Liquid Chromatography Tandem Mass

The method of simultaneous quantification some of Human Milk Oligosaccharide in dietary supplements by LC-MS/MS is an accurate and effective method to quickly determine the content of 2'-Fucosyllactose (2 '-FL), Lacto-N-neotetraose (LNnT), Lacto-N-tetraose (LNT), 3'-Siallylactose (3'-SL) and 6'-Siallylactose (6'-SL) in both dietary supplements powder and liquid. The method has been developed and validated follow the AOAC International guidelines. The mobile phase system consists of 2 channels: channel A (0.1% formic acid) and channel B (acetonitril) connected to the HILIC column (3.5 μm, 2.1mm × 150 mm) and the MS detector. The time analysis is 10 minutes, this method can identify all 5 substances belonging to the group HMOs. The detection limit and quantitative limit for all 5’-FL, LNnT, LNT, 3’-SL, 6’-SL were 4 mg/kg and 10 mg/kg, respectively. The linear range of the method ranges from 0.4 µg/mL to 40 µg/mL. Other validation parameters include the accuracy (R% 98.8 -103%); The precision (RSD% 1.69 - 5.54%) can meet the requirement of AOAC. The method was applied in practice to analyze 25 supplementary food samples on the market gives the results of analyzing total HMOs in powdered samples about 0.1 – 0.3 g/100g and for liquid samples about 0.01 – 0.03 g/100mL.

Ionic liquids versus triethylamine as mobile phase additives in the analysis of β-blockers

2006 ◽  
Vol 1119 (1-2) ◽  
pp. 202-208 ◽  
Author(s):  
M.J. Ruiz-Angel ◽  
S. Carda-Broch ◽  
A. Berthod
Keyword(s):  
Ionic Liquids ◽  
Mobile Phase ◽  
Mobile Phase Additives ◽  
Β Blockers

scholarly journals Synthesis of MoS2 nanosheets for mercury speciation analysis by HPLC-UV-HG-AFS

RSC Advances ◽  
2018 ◽  
Vol 8 (33) ◽  
pp. 18364-18371 ◽  
Author(s):  
Xingsu Gao ◽  
Jiayong Dai ◽  
Hongyan Zhao ◽  
Jun Zhu ◽  
Lan Luo ◽  
...  
Keyword(s):  
Solid Phase Extraction ◽  
Molybdenum Disulfide ◽  
Solid Phase ◽  
Speciation Analysis ◽  
Mercury Speciation ◽  
Phase Extraction ◽  
Mos2 Nanosheets ◽  
Ultra Trace ◽  
Molybdenum Disulfide Nanosheets ◽  
As Solid Phase

As-synthesized few-layered molybdenum disulfide nanosheets were used as solid-phase extraction absorbent for ultra-trace mercury speciation analysis by HPLC-UV-HG-AFS.

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